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Association between obesity and acute severity among patients hospitalized for asthma exacerbation
https://asahikawa-med.repo.nii.ac.jp/records/6064
https://asahikawa-med.repo.nii.ac.jp/records/6064f2354ea4-3e20-4105-b70e-219fc438fcd9
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
7217.pdf (167.8 kB)
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| Item type | 学位論文 / Thesis or Dissertation_02(1) | |||||||||
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| 公開日 | 2019-03-26 | |||||||||
| タイトル | ||||||||||
| タイトル | Association between obesity and acute severity among patients hospitalized for asthma exacerbation | |||||||||
| 言語 | en | |||||||||
| 言語 | ||||||||||
| 言語 | jpn | |||||||||
| キーワード | ||||||||||
| 主題Scheme | Other | |||||||||
| 主題 | Acute severity | |||||||||
| キーワード | ||||||||||
| 主題Scheme | Other | |||||||||
| 主題 | Adults | |||||||||
| キーワード | ||||||||||
| 主題Scheme | Other | |||||||||
| 主題 | Asthma | |||||||||
| キーワード | ||||||||||
| 主題Scheme | Other | |||||||||
| 主題 | Hospitalization | |||||||||
| キーワード | ||||||||||
| 主題Scheme | Other | |||||||||
| 主題 | Obesity | |||||||||
| 資源タイプ | ||||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_46ec | |||||||||
| 資源タイプ | thesis | |||||||||
| その他（別言語等）のタイトル | ||||||||||
| その他のタイトル | 気管支喘息の急性増悪による入院患者の急性期における重傷度と肥満の関連性の検討 | |||||||||
| 著者 |
久良木, ルーテ彩来
× 久良木, ルーテ彩来
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| 著者 ローマ字 | ||||||||||
| Kyuragi, Rutesara(Sarah Luthe) | ||||||||||
| 書誌情報 |
The Journal of Allergy and Clinical Immunology 巻 6, 号 6, p. 1936-1941, 発行日 2018-01-01 |
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| ISSN | ||||||||||
| 収録物識別子タイプ | ISSN | |||||||||
| 収録物識別子 | 2213-2198 | |||||||||
| DOI | ||||||||||
| 識別子タイプ | DOI | |||||||||
| 関連識別子 | 10.1016/j.jaip.2018.02.001 | |||||||||
| 識別番号 その他 | ||||||||||
| 内容記述タイプ | Other | |||||||||
| 内容記述 | PMID：29452277 | |||||||||
| 学位授与番号 | ||||||||||
| 学位授与番号 | 10107B478 | |||||||||
| 学位名 | ||||||||||
| 学位名 | 博士（医学） | |||||||||
| 学位授与機関 | ||||||||||
| 学位授与機関名 | 旭川医科大学 | |||||||||
| 抄録 | ||||||||||
| 内容記述タイプ | Abstract | |||||||||
| 内容記述 | BACKGROUND: \nAlthough studies have demonstrated relations between obesity and incident asthma, little is known about the association of obesity with acute severity in adults hospitalized for asthma exacerbation. OBJECTIVES: \nTo investigate the association of obesity with acute severity of asthma exacerbation. METHODS: \nThis is a retrospective cohort study using population-based data of 8 geographically diverse US states from 2010 through 2013. We included adults (age 18-54 years) hospitalized for asthma exacerbation. The outcome measures were markers of acute severity-use of mechanical ventilation (defined by noninvasive positive pressure ventilation and/or invasive mechanical ventilation) and hospital length of stay. To determine the association of obesity with each outcome, we fit multivariable models adjusting for patient-level confounders (eg, age, sex, race/ethnicity, primary insurance, quartiles for household income, residential status, and comorbidities) and potential patient clustering within hospitals. RESULTS: \nAmong the 72,086 patients hospitalized for asthma exacerbation, 24% were obese. Obesity was associated with a significantly higher risk of any mechanical ventilation use (8.3% vs 5.0%; adjusted odds ratio [OR], 1.77; 95% CI, 1.63-1.92; P < .001) driven by the higher risk of noninvasive positive pressure ventilation use (7.2% vs 3.4%; adjusted OR, 2.14; 95% CI, 1.96-2.35; P < .001). Likewise, obese patients were more likely to have a hospital length of stay of 3 or more days compared with nonobese patients (59.4% vs 46.5%; adjusted OR, 1.37; 95% CI, 1.32-1.43; P < .001). These findings were consistent with stratifications by age, sex, and race/ethnicity. CONCLUSIONS: \nIn this population-based study of adults hospitalized for asthma exacerbation, obesity was associated with higher acute severity. |
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| 資源タイプ | ||||||||||
| 内容記述タイプ | Other | |||||||||
| 内容記述 | application/pdf | |||||||||
| フォーマット | ||||||||||
| 内容記述タイプ | Other | |||||||||
| 内容記述 | application/pdf | |||||||||
