@misc{oai:asahikawa-med.repo.nii.ac.jp:00006064,
 author = {久良木, ルーテ彩来},
 month = {Jan},
 note = {PMID：29452277, BACKGROUND:
\nAlthough studies have demonstrated relations between obesity and incident asthma, little is known about the association of obesity with acute severity in adults hospitalized for asthma exacerbation.
OBJECTIVES:
\nTo investigate the association of obesity with acute severity of asthma exacerbation.
METHODS:
\nThis is a retrospective cohort study using population-based data of 8 geographically diverse US states from 2010 through 2013. We included adults (age 18-54 years) hospitalized for asthma exacerbation. The outcome measures were markers of acute severity-use of mechanical ventilation (defined by noninvasive positive pressure ventilation and/or invasive mechanical ventilation) and hospital length of stay. To determine the association of obesity with each outcome, we fit multivariable models adjusting for patient-level confounders (eg, age, sex, race/ethnicity, primary insurance, quartiles for household income, residential status, and comorbidities) and potential patient clustering within hospitals.
RESULTS:
\nAmong the 72,086 patients hospitalized for asthma exacerbation, 24% were obese. Obesity was associated with a significantly higher risk of any mechanical ventilation use (8.3% vs 5.0%; adjusted odds ratio [OR], 1.77; 95% CI, 1.63-1.92; P < .001) driven by the higher risk of noninvasive positive pressure ventilation use (7.2% vs 3.4%; adjusted OR, 2.14; 95% CI, 1.96-2.35; P < .001). Likewise, obese patients were more likely to have a hospital length of stay of 3 or more days compared with nonobese patients (59.4% vs 46.5%; adjusted OR, 1.37; 95% CI, 1.32-1.43; P < .001). These findings were consistent with stratifications by age, sex, and race/ethnicity.
CONCLUSIONS:
\nIn this population-based study of adults hospitalized for asthma exacerbation, obesity was associated with higher acute severity., application/pdf, application/pdf},
 title = {Association between obesity and acute severity among patients hospitalized for asthma exacerbation},
 year = {2018},
 yomi = {キュウラギ, ルーテサラ}
}