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Comparison of the serological tests ICT and ELISA for the diagnosis of alveolar echinococcosis in France.
https://asahikawa-med.repo.nii.ac.jp/records/5718
https://asahikawa-med.repo.nii.ac.jp/records/571895d79519-a86c-4cb2-9589-9feb88142c6f
名前 / ファイル | ライセンス | アクション |
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Item type | 学術雑誌論文 / Journal Article_02(1) | |||||
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公開日 | 2017-09-12 | |||||
タイトル | ||||||
タイトル | Comparison of the serological tests ICT and ELISA for the diagnosis of alveolar echinococcosis in France. | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | alveolar echinococcosis | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | diagnosis | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | rEm18 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | immunochromatography | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | rapid test | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | rEm18-ELISA and Em2-Em18-ELISA tests | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Jenny, Knapp
× Jenny, Knapp× 迫, 康仁× Frédéric, Grenouillet× Solange, Bresson-Hadni× Carine, Richou× Houssein, Gbaguidi-Haore× 伊藤, 亮× Laurence, Millon |
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著者 ローマ字 | ||||||
著者 ローマ字 | ||||||
値 | Sako, Yasuhito | |||||
著者 ローマ字 | ||||||
著者 ローマ字 | ||||||
著者 ローマ字 | ||||||
著者 ローマ字 | ||||||
著者 ローマ字 | ||||||
値 | Ito, Akira | |||||
書誌情報 |
Parasite 号 21, p. 1-6, 発行日 2014-07-01 |
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ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 1252-607X | |||||
DOI | ||||||
関連タイプ | isIdenticalTo | |||||
識別子タイプ | DOI | |||||
関連識別子 | 10.1051/parasite/2014037. | |||||
識別番号 その他 | ||||||
内容記述タイプ | Other | |||||
内容記述 | PMID:25058754 | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Serological diagnosis of alveolar echinococcosis (AE) is a key element for efficient patient treatment management. A rapid immunochromatography test kit (ICT) using the recombinant Em18 antigen (rEm18) was recently developed. The aim of our study was to assess this test on a panel of sera from French patients with alveolar echinococcosis and control patients. In a blind test, a total of 112 serum samples were tested including samples of AE (n = 30), cystic echinococcosis [CE] (n = 15), and polycystic echinococcosis [PE] (n = 1). For the comparison, 66 sera from patients with hepatocarcinoma, fascioliasis, toxocariasis, Caroli's disease, or autoimmune chronic active hepatitis were used. The diagnostic test sets we used were the rEm18-ICT and two validated ELISAs with rEm18 and Em2-Em18 antigens, respectively. For the ICT, 27/30 sera from AE patients, 4/15 sera from CE patients and the PE patient serum were positive. One serum from the control panel (toxocariasis) was positive for the ICT. The rEm18-ICT sensitivity (90.0%) and specificity (92.7%) for detection of Em18-specific antibodies confirmed it as a relevant tool for AE diagnosis. The rEm18-ELISA had a sensitivity of 86.7% and specificity of 91.5%, and the Em2-Em18-ELISA had a sensitivity of 96.7% and specificity of 87.8%. However, when AE patient sera are recorded as weak in intensity with the ICT, we recommend a double reading and use of a reference sample if the ICT is used for patient follow-up. | |||||
注記 | ||||||
内容記述タイプ | Other | |||||
内容記述 | This is an Open Access article distributed under the terms of the Creative Commons Attribution License | |||||
資源タイプ | ||||||
内容記述タイプ | Other | |||||
内容記述 | text | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
フォーマット | ||||||
内容記述タイプ | Other | |||||
内容記述 | application/pdf | |||||
ID(XooNIps) | ||||||
値 | 25058754 | |||||
閲覧数(XooNIps) | ||||||
値 | 478 | |||||
ダウンロード数(XooNIps) | ||||||
値 | 587 |