{"created":"2023-06-19T11:24:55.542560+00:00","id":5718,"links":{},"metadata":{"_buckets":{"deposit":"f8a05382-d454-4d56-9140-0158a233026a"},"_deposit":{"created_by":1,"id":"5718","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"5718"},"status":"published"},"_oai":{"id":"oai:asahikawa-med.repo.nii.ac.jp:00005718","sets":["7","7:24"]},"author_link":["17931","17937","17932","17934","17930","17933","17935","17936"],"item_5_biblio_info_21":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2014-07-01","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"21","bibliographicPageEnd":"6","bibliographicPageStart":"1","bibliographic_titles":[{"bibliographic_title":"Parasite"}]}]},"item_5_description_28":{"attribute_name":"識別番号 その他","attribute_value_mlt":[{"subitem_description":"PMID:25058754","subitem_description_type":"Other"}]},"item_5_description_33":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Serological diagnosis of alveolar echinococcosis (AE) is a key element for efficient patient treatment management. A rapid immunochromatography test kit (ICT) using the recombinant Em18 antigen (rEm18) was recently developed. The aim of our study was to assess this test on a panel of sera from French patients with alveolar echinococcosis and control patients. In a blind test, a total of 112 serum samples were tested including samples of AE (n = 30), cystic echinococcosis [CE] (n = 15), and polycystic echinococcosis [PE] (n = 1). For the comparison, 66 sera from patients with hepatocarcinoma, fascioliasis, toxocariasis, Caroli's disease, or autoimmune chronic active hepatitis were used. The diagnostic test sets we used were the rEm18-ICT and two validated ELISAs with rEm18 and Em2-Em18 antigens, respectively. For the ICT, 27/30 sera from AE patients, 4/15 sera from CE patients and the PE patient serum were positive. One serum from the control panel (toxocariasis) was positive for the ICT. The rEm18-ICT sensitivity (90.0%) and specificity (92.7%) for detection of Em18-specific antibodies confirmed it as a relevant tool for AE diagnosis. The rEm18-ELISA had a sensitivity of 86.7% and specificity of 91.5%, and the Em2-Em18-ELISA had a sensitivity of 96.7% and specificity of 87.8%. However, when AE patient sera are recorded as weak in intensity with the ICT, we recommend a double reading and use of a reference sample if the ICT is used for patient follow-up.","subitem_description_type":"Abstract"}]},"item_5_description_36":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"This is an Open Access article distributed under the terms of the Creative Commons Attribution License","subitem_description_type":"Other"}]},"item_5_description_37":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"subitem_description":"text","subitem_description_type":"Other"}]},"item_5_description_41":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_5_relation_24":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"10.1051/parasite/2014037.","subitem_relation_type_select":"DOI"}}]},"item_5_source_id_22":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1252-607X","subitem_source_identifier_type":"ISSN"}]},"item_5_text_44":{"attribute_name":"ID(XooNIps)","attribute_value_mlt":[{"subitem_text_value":"25058754"}]},"item_5_text_54":{"attribute_name":"閲覧数(XooNIps)","attribute_value_mlt":[{"subitem_text_value":"478"}]},"item_5_text_55":{"attribute_name":"ダウンロード数(XooNIps)","attribute_value_mlt":[{"subitem_text_value":"587"}]},"item_5_text_7":{"attribute_name":"著者 ローマ字","attribute_value_mlt":[{"subitem_text_value":"&EMPTY&"},{"subitem_text_value":"Sako, Yasuhito"},{"subitem_text_value":"&EMPTY&"},{"subitem_text_value":"&EMPTY&"},{"subitem_text_value":"&EMPTY&"},{"subitem_text_value":"&EMPTY&"},{"subitem_text_value":"Ito, Akira"}]},"item_5_version_type_38":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Jenny, Knapp"}],"nameIdentifiers":[{"nameIdentifier":"17930","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"迫, 康仁"},{"creatorName":"サコ, ヤスヒト","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"17931","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Frédéric, Grenouillet"}],"nameIdentifiers":[{"nameIdentifier":"17932","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Solange, Bresson-Hadni"}],"nameIdentifiers":[{"nameIdentifier":"17933","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Carine, Richou"}],"nameIdentifiers":[{"nameIdentifier":"17934","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Houssein, Gbaguidi-Haore"}],"nameIdentifiers":[{"nameIdentifier":"17935","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"伊藤, 亮"},{"creatorName":"イトウ, アキラ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"17936","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Laurence, Millon"}],"nameIdentifiers":[{"nameIdentifier":"17937","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2021-07-06"}],"displaytype":"detail","filename":"6784.pdf","filesize":[{"value":"664.6 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"6784.pdf","url":"https://asahikawa-med.repo.nii.ac.jp/record/5718/files/6784.pdf"},"version_id":"37d8005f-f1fd-4f5c-a3d9-90b47480de00"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"alveolar echinococcosis","subitem_subject_scheme":"Other"},{"subitem_subject":"diagnosis","subitem_subject_scheme":"Other"},{"subitem_subject":"rEm18","subitem_subject_scheme":"Other"},{"subitem_subject":"immunochromatography","subitem_subject_scheme":"Other"},{"subitem_subject":"rapid test","subitem_subject_scheme":"Other"},{"subitem_subject":"rEm18-ELISA and Em2-Em18-ELISA tests","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Comparison of the serological tests ICT and ELISA for the diagnosis of alveolar echinococcosis in France.","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Comparison of the serological tests ICT and ELISA for the diagnosis of alveolar echinococcosis in France."}]},"item_type_id":"5","owner":"1","path":["6","7","24"],"pubdate":{"attribute_name":"公開日","attribute_value":"2017-09-12"},"publish_date":"2017-09-12","publish_status":"0","recid":"5718","relation_version_is_last":true,"title":["Comparison of the serological tests ICT and ELISA for the diagnosis of alveolar echinococcosis in France."],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-06-19T12:14:24.533819+00:00"}