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Serological validation of an alveolar echinococcosis rat model with a single hepatic lesion.
https://asahikawa-med.repo.nii.ac.jp/records/5714
https://asahikawa-med.repo.nii.ac.jp/records/571477fba130-64ff-4e4e-8018-7a7ddb63804e
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
6780.pdf (4.9 MB)
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| Item type | 学術雑誌論文 / Journal Article_02(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2017-09-12 | |||||
| タイトル | ||||||
| タイトル | Serological validation of an alveolar echinococcosis rat model with a single hepatic lesion. | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Echinococcus multilocularis | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Em18 | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | rat model | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | serology | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| 著者 |
山下, 真路
× 山下, 真路× 今川, 智敬× 迫, 康仁× 岡本, 宗裕× 柳田, 哲矢× 岡本, 芳晴× 柄, 武志× 大崎, 智弘× 伊藤, 亮 |
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| 著者 ローマ字 | ||||||
| 値 | Yamashita, Masamichi | |||||
| 著者 ローマ字 | ||||||
| 値 | Imagawa, Tomohiro | |||||
| 著者 ローマ字 | ||||||
| 値 | Sako, Yasuhito | |||||
| 著者 ローマ字 | ||||||
| 値 | Okamoto, Munehiro | |||||
| 著者 ローマ字 | ||||||
| 値 | Yanagida, Tetsuya | |||||
| 著者 ローマ字 | ||||||
| 値 | Okamoto, Yoshiharu | |||||
| 著者 ローマ字 | ||||||
| 値 | Tsuka, Takeshi | |||||
| 著者 ローマ字 | ||||||
| 値 | Osaki, Tomohiro | |||||
| 著者 ローマ字 | ||||||
| 値 | Ito, Akira | |||||
| 書誌情報 |
The Journal of Veterinary Medical Science 巻 79, 号 2, p. 308-313, 発行日 2017-02-01 |
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| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 0916-7250 | |||||
| DOI | ||||||
| 関連タイプ | isIdenticalTo | |||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | 10.1292/jvms.16-0513. | |||||
| 識別番号 その他 | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | PMID：27890868 | |||||
| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Serology is important for the diagnosis and follow-up of human alveolar echinococcosis (AE). However, patient conditions are highly variable among those with AE, and antibody responses in serological follow-up have not been well-defined. We recently described a new AE rat model established by implantation of small AE tissue into a single arbitrary location in the liver; no metastasis and dissemination were observed. In the present study, we examined the serological characteristics in our rat model before and after surgical treatment. The results showed that antibody responses against crude antigens were increased at one month after transplantation and similar to those of other model animals. For the antigen Em18, antibody responses were slower in our rat model than in other animal models. After surgical resection, changes in antibody responses against Em18 were similar to those observed in human patients with AE. Because of the slow growth of lesions, establishment of a single hepatic lesion and patterns of antibody responses, our rat model may be useful for clarifying follow-up serodiagnoses in human AE and determining the mechanisms of multi-organ involvement by primary infection with oncospheres rather than metastasis. | |||||
| 注記 | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | This is an open access article under the CC BY-NC-ND license. (http://creativecommons.org/licenses/by-nc-nd/4.0/). | |||||
| 資源タイプ | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | text | |||||
| 著者版フラグ | ||||||
| 出版タイプ | VoR | |||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
| フォーマット | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | application/pdf | |||||
| ID(XooNIps) | ||||||
| 値 | 27890868 | |||||
| 閲覧数(XooNIps) | ||||||
| 値 | 397 | |||||
| ダウンロード数(XooNIps) | ||||||
| 値 | 401 | |||||
