{"created":"2023-06-19T11:24:55.364167+00:00","id":5714,"links":{},"metadata":{"_buckets":{"deposit":"5b879f4c-79e2-4c87-9c89-bc2a95b448ba"},"_deposit":{"created_by":1,"id":"5714","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"5714"},"status":"published"},"_oai":{"id":"oai:asahikawa-med.repo.nii.ac.jp:00005714","sets":["7","7:24"]},"author_link":["17902","17894","17896","17901","17900","17895","17899","17897","17898"],"item_5_biblio_info_21":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2017-02-01","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"2","bibliographicPageEnd":"313","bibliographicPageStart":"308","bibliographicVolumeNumber":"79","bibliographic_titles":[{"bibliographic_title":"The Journal of Veterinary Medical Science"}]}]},"item_5_description_28":{"attribute_name":"識別番号 その他","attribute_value_mlt":[{"subitem_description":"PMID：27890868","subitem_description_type":"Other"}]},"item_5_description_33":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Serology is important for the diagnosis and follow-up of human alveolar echinococcosis (AE). However, patient conditions are highly variable among those with AE, and antibody responses in serological follow-up have not been well-defined. We recently described a new AE rat model established by implantation of small AE tissue into a single arbitrary location in the liver; no metastasis and dissemination were observed. In the present study, we examined the serological characteristics in our rat model before and after surgical treatment. The results showed that antibody responses against crude antigens were increased at one month after transplantation and similar to those of other model animals. For the antigen Em18, antibody responses were slower in our rat model than in other animal models. After surgical resection, changes in antibody responses against Em18 were similar to those observed in human patients with AE. Because of the slow growth of lesions, establishment of a single hepatic lesion and patterns of antibody responses, our rat model may be useful for clarifying follow-up serodiagnoses in human AE and determining the mechanisms of multi-organ involvement by primary infection with oncospheres rather than metastasis.","subitem_description_type":"Abstract"}]},"item_5_description_36":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"This is an open access article under the CC BY-NC-ND license. (http://creativecommons.org/licenses/by-nc-nd/4.0/).","subitem_description_type":"Other"}]},"item_5_description_37":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"subitem_description":"text","subitem_description_type":"Other"}]},"item_5_description_41":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_5_relation_24":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"10.1292/jvms.16-0513.","subitem_relation_type_select":"DOI"}}]},"item_5_source_id_22":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0916-7250","subitem_source_identifier_type":"ISSN"}]},"item_5_text_44":{"attribute_name":"ID(XooNIps)","attribute_value_mlt":[{"subitem_text_value":"27890868"}]},"item_5_text_54":{"attribute_name":"閲覧数(XooNIps)","attribute_value_mlt":[{"subitem_text_value":"397"}]},"item_5_text_55":{"attribute_name":"ダウンロード数(XooNIps)","attribute_value_mlt":[{"subitem_text_value":"401"}]},"item_5_text_7":{"attribute_name":"著者 ローマ字","attribute_value_mlt":[{"subitem_text_value":"Yamashita, Masamichi"},{"subitem_text_value":"Imagawa, Tomohiro"},{"subitem_text_value":"Sako, Yasuhito"},{"subitem_text_value":"Okamoto, Munehiro"},{"subitem_text_value":"Yanagida, Tetsuya"},{"subitem_text_value":"Okamoto, Yoshiharu"},{"subitem_text_value":"Tsuka, Takeshi"},{"subitem_text_value":"Osaki, Tomohiro"},{"subitem_text_value":"Ito, Akira"}]},"item_5_version_type_38":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"山下, 真路"},{"creatorName":"ヤマシタ, マサミチ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"17894","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"今川, 智敬"},{"creatorName":"イマガワ, トモヒロ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"17895","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"迫, 康仁"},{"creatorName":"サコ, ヤスヒト","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"17896","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"岡本, 宗裕"},{"creatorName":"オカモト, ムネヒロ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"17897","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"柳田, 哲矢"},{"creatorName":"ヤナギダ, テツヤ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"17898","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"岡本, 芳晴"},{"creatorName":"オカモト, ヨシハル","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"17899","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"柄, 武志"},{"creatorName":"ツカ, タケシ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"17900","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"大崎, 智弘"},{"creatorName":"オオサキ, トモヒロ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"17901","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"伊藤, 亮"},{"creatorName":"イトウ, アキラ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"17902","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2021-07-06"}],"displaytype":"detail","filename":"6780.pdf","filesize":[{"value":"4.9 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"6780.pdf","url":"https://asahikawa-med.repo.nii.ac.jp/record/5714/files/6780.pdf"},"version_id":"696d1923-9566-4084-a08b-c07b69660d14"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Echinococcus multilocularis","subitem_subject_scheme":"Other"},{"subitem_subject":"Em18","subitem_subject_scheme":"Other"},{"subitem_subject":"rat model","subitem_subject_scheme":"Other"},{"subitem_subject":"serology","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Serological validation of an alveolar echinococcosis rat model with a single hepatic lesion.","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Serological validation of an alveolar echinococcosis rat model with a single hepatic lesion."}]},"item_type_id":"5","owner":"1","path":["6","7","24"],"pubdate":{"attribute_name":"公開日","attribute_value":"2017-09-12"},"publish_date":"2017-09-12","publish_status":"0","recid":"5714","relation_version_is_last":true,"title":["Serological validation of an alveolar echinococcosis rat model with a single hepatic lesion."],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-06-19T12:14:30.228135+00:00"}