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Dutasteride improves bone mineral density in male patients with lower urinary tract symptoms and prostatic enlargement: a preliminary study
https://asahikawa-med.repo.nii.ac.jp/records/5513
https://asahikawa-med.repo.nii.ac.jp/records/551378f8aab9-4aec-4316-81f2-8678926cf9bd
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
6524.pdf (306.7 kB)
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| Item type | 学術雑誌論文 / Journal Article_02(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2016-08-16 | |||||
| タイトル | ||||||
| タイトル | Dutasteride improves bone mineral density in male patients with lower urinary tract symptoms and prostatic enlargement: a preliminary study | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Benign prostatic hyperplasia | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | bone mineral density | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | dutasteride | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| 著者 |
和田, 直樹
× 和田, 直樹× 橋爪, 和純× 松本, 成史× 柿崎, 秀宏 |
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| 著者 ローマ字 | ||||||
| 値 | Wada, Naoki | |||||
| 著者 ローマ字 | ||||||
| 値 | Hashizume, Kazumi | |||||
| 著者 ローマ字 | ||||||
| 値 | Matsumoto, Seiji | |||||
| 著者 ローマ字 | ||||||
| 値 | Kakizaki, Hidehiro | |||||
| 書誌情報 |
The aging male : the official journal of the International Society for the Study of the Aging Male. 巻 19, 号 1, p. 12-14, 発行日 2015-07-01 |
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| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 1368-5538 | |||||
| DOI | ||||||
| 関連タイプ | isVersionOf | |||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | 10.3109/13685538.2015.1072155 | |||||
| 識別番号 その他 | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | PMID:26225793 | |||||
| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | We studied the effect of dutasteride on bone mineral density (BMD) in aging male patients with lower urinary tract symptoms (LUTS) and prostatic enlargement. METHODS: \nWe prospectively studied 17 patients with LUTS and prostatic enlargement. Before and 1 year after dutasteride (0.5 mg daily), we assessed International Prostate Symptom Score (IPSS), prostatic volume (PV), serum prostatic-specific antigen (PSA) and testosterone. BMD in the lumbar and femur was measured by DEXA method. RESULTS: \nDutasteride significantly reduced PV (from 51 ± 24 to 34 ± 17 ml, p < 0.001) and improved IPSS (from 15.1 ± 9.8 to 11.7 ± 10.3, p < 0.05). Serum PSA was significantly decreased (from 3.2 ± 2.6 to 1.0 ± 0.8 ng/ml, p < 0.001), while serum testosterone "was not changed" significantly. BMD of the lumbar "was not changed" significantly after dutasteride. BMD of the femur was significantly improved (from 0.75 ± 0.14 to 0.82 ± 0.16 g/cm(2), p < 0.01). In nine patients whose testosterone was increased after dutasteride, BMD of the lumbar (from 1.18 ± 0.26 to 1.22 ± 0.25 g/cm(2), p < 0.05) and femur (from 0.76 ± 0.12 to 0.84 ± 0.16 g/cm(2), p < 0.05) was significantly improved. CONCLUSIONS: \nDutasteride has a potential to improve BMD with elevation of serum testosterone in aging male patients with LUTS and prostatic enlargement. |
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| 資源タイプ | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | text | |||||
| 著者版フラグ | ||||||
| 出版タイプ | AM | |||||
| 出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||
| フォーマット | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | application/pdf | |||||
| ID(XooNIps) | ||||||
| 値 | 26225793 | |||||
| 閲覧数(XooNIps) | ||||||
| 値 | 676 | |||||
| ダウンロード数(XooNIps) | ||||||
| 値 | 423 | |||||
