{"created":"2023-06-19T11:24:45.108084+00:00","id":5513,"links":{},"metadata":{"_buckets":{"deposit":"2f17ed77-c09d-4f84-9bf1-f153c7e66c0f"},"_deposit":{"created_by":1,"id":"5513","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"5513"},"status":"published"},"_oai":{"id":"oai:asahikawa-med.repo.nii.ac.jp:00005513","sets":["7","7:24"]},"author_link":["17235","17236","17233","17234"],"item_5_biblio_info_21":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2015-07-01","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1","bibliographicPageEnd":"14","bibliographicPageStart":"12","bibliographicVolumeNumber":"19","bibliographic_titles":[{"bibliographic_title":"The aging male : the official journal of the International Society for the Study of the Aging Male."}]}]},"item_5_description_28":{"attribute_name":"識別番号 その他","attribute_value_mlt":[{"subitem_description":"PMID:26225793","subitem_description_type":"Other"}]},"item_5_description_33":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"We studied the effect of dutasteride on bone mineral density (BMD) in aging male patients with lower urinary tract symptoms (LUTS) and prostatic enlargement.\nMETHODS:\n\\nWe prospectively studied 17 patients with LUTS and prostatic enlargement. Before and 1 year after dutasteride (0.5 mg daily), we assessed International Prostate Symptom Score (IPSS), prostatic volume (PV), serum prostatic-specific antigen (PSA) and testosterone. BMD in the lumbar and femur was measured by DEXA method.\nRESULTS:\n\\nDutasteride significantly reduced PV (from 51 ± 24 to 34 ± 17 ml, p < 0.001) and improved IPSS (from 15.1 ± 9.8 to 11.7 ± 10.3, p < 0.05). Serum PSA was significantly decreased (from 3.2 ± 2.6 to 1.0 ± 0.8 ng/ml, p < 0.001), while serum testosterone \"was not changed\" significantly. BMD of the lumbar \"was not changed\" significantly after dutasteride. BMD of the femur was significantly improved (from 0.75 ± 0.14 to 0.82 ± 0.16 g/cm(2), p < 0.01). In nine patients whose testosterone was increased after dutasteride, BMD of the lumbar (from 1.18 ± 0.26 to 1.22 ± 0.25 g/cm(2), p < 0.05) and femur (from 0.76 ± 0.12 to 0.84 ± 0.16 g/cm(2), p < 0.05) was significantly improved.\nCONCLUSIONS:\n\\nDutasteride has a potential to improve BMD with elevation of serum testosterone in aging male patients with LUTS and prostatic enlargement.","subitem_description_type":"Abstract"}]},"item_5_description_37":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"subitem_description":"text","subitem_description_type":"Other"}]},"item_5_description_41":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_5_relation_24":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isVersionOf","subitem_relation_type_id":{"subitem_relation_type_id_text":"10.3109/13685538.2015.1072155","subitem_relation_type_select":"DOI"}}]},"item_5_source_id_22":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1368-5538","subitem_source_identifier_type":"ISSN"}]},"item_5_text_44":{"attribute_name":"ID(XooNIps)","attribute_value_mlt":[{"subitem_text_value":"26225793"}]},"item_5_text_54":{"attribute_name":"閲覧数(XooNIps)","attribute_value_mlt":[{"subitem_text_value":"676"}]},"item_5_text_55":{"attribute_name":"ダウンロード数(XooNIps)","attribute_value_mlt":[{"subitem_text_value":"423"}]},"item_5_text_7":{"attribute_name":"著者 ローマ字","attribute_value_mlt":[{"subitem_text_value":"Wada, Naoki"},{"subitem_text_value":"Hashizume, Kazumi"},{"subitem_text_value":"Matsumoto, Seiji"},{"subitem_text_value":"Kakizaki, Hidehiro"}]},"item_5_version_type_38":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"和田, 直樹"},{"creatorName":"ワダ, ナオキ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"17233","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"橋爪, 和純"},{"creatorName":"ハシヅメ, カズミ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"17234","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"松本, 成史"},{"creatorName":"マツモト, セイジ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"17235","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"柿崎, 秀宏"},{"creatorName":"カキザキ, ヒデヒロ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"17236","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2021-07-06"}],"displaytype":"detail","filename":"6524.pdf","filesize":[{"value":"306.7 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"6524.pdf","url":"https://asahikawa-med.repo.nii.ac.jp/record/5513/files/6524.pdf"},"version_id":"68ad4bc1-f2ee-44fb-bc30-8e208b242e22"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Benign prostatic hyperplasia","subitem_subject_scheme":"Other"},{"subitem_subject":"bone mineral density","subitem_subject_scheme":"Other"},{"subitem_subject":"dutasteride","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Dutasteride improves bone mineral density in male patients with lower urinary tract symptoms and prostatic enlargement: a preliminary study","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Dutasteride improves bone mineral density in male patients with lower urinary tract symptoms and prostatic enlargement: a preliminary study"}]},"item_type_id":"5","owner":"1","path":["6","7","24"],"pubdate":{"attribute_name":"公開日","attribute_value":"2016-08-16"},"publish_date":"2016-08-16","publish_status":"0","recid":"5513","relation_version_is_last":true,"title":["Dutasteride improves bone mineral density in male patients with lower urinary tract symptoms and prostatic enlargement: a preliminary study"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-06-19T12:19:32.675107+00:00"}