| Item type |
学術雑誌論文 / Journal Article_02(1) |
| 公開日 |
2015-09-08 |
| タイトル |
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|
タイトル |
Tranexamic acid-induced ligneous conjunctivitis with renal failure showed reversible hypoplasminogenaemia. |
| 言語 |
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言語 |
eng |
| 資源タイプ |
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資源タイプ |
journal article |
| 著者 |
宋, 勇錫
泉, 直宏
Luke, B Potts
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| 著者 ローマ字 |
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Song, Young-Seok |
| 著者 ローマ字 |
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Izumi, Naohiro |
| 書誌情報 |
BMJ case reports
発行日 2014-05-01
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| ISSN |
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収録物識別子タイプ |
ISSN |
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収録物識別子 |
1757-790X |
| DOI |
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関連タイプ |
isVersionOf |
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識別子タイプ |
DOI |
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関連識別子 |
10.1136/bcr-2014-204138. |
| 識別番号 その他 |
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内容記述タイプ |
Other |
|
内容記述 |
PMID:24842363 |
| 抄録 |
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内容記述タイプ |
Abstract |
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内容記述 |
Ligneous conjunctivitis is a rare severe conjunctivitis characterised by fibrin-rich, 'woody', pseudomembranes on the tarsal conjunctiva complicated by congenital hypoplasminogenaemia. A previous report suggested that ligneous conjunctivitis may result from tranexamic acid (TA)-induced 'secondary' hypoplasminogenaemia. However, the serum plasminogen level has not been confirmed in that scenario. We report for the first time a case of TA-induced ligneous conjunctivitis with reversible hypoplasminogenaemia. A 70-year-old woman developed a gastric ulcer that was treated with oral TA. After 5 weeks of treatment, the patient presented with bilateral pale yellow pseudomembranes on the palpebral conjunctivae. Haematological analysis showed hypoplasminogenaemia. We diagnosed ligneous conjunctivitis. TA was discontinued after 14 weeks after the gastric ulcer symptoms resolved. Six weeks after discontinuation of therapy, the pseudomembranes regressed and the serum plasminogen level returned to the normal range. TA should be considered a possible aetiology in the setting of unresolving ligneous conjunctivitis. |
| 資源タイプ |
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内容記述タイプ |
Other |
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資源タイプ |
text |
| 著者版フラグ |
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出版タイプ |
AM |
| フォーマット |
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内容記述タイプ |
Other |
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内容記述 |
application/pdf |
| ID(XooNIps) |
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24842363 |
| 閲覧数(XooNIps) |
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| ダウンロード数(XooNIps) |
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545 |
6196.pdf (133.1 kB)
