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Co-localization of TRPV2 and insulin-like growth factor-I receptor in olfactory neurons in adult and fetal mouse.
https://asahikawa-med.repo.nii.ac.jp/records/5219
https://asahikawa-med.repo.nii.ac.jp/records/5219b1a3fc66-bc07-4dac-ac15-f8cd34b0d55b
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
6118.pdf (1.6 MB)
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| Item type | 学術雑誌論文 / Journal Article_02(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2015-05-19 | |||||
| タイトル | ||||||
| タイトル | Co-localization of TRPV2 and insulin-like growth factor-I receptor in olfactory neurons in adult and fetal mouse. | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | olfactory neuron | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | olfactory epithelium | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | olfactory bulb | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | insulin-like growth factor-I receptor | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | transient receptor potential V2 | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| 著者 |
松井, 等
× 松井, 等× 野口, 智弘× 高草木, 薫× 柏柳, 誠 |
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| 著者 ローマ字 | ||||||
| 値 | Matsui, Hitoshi | |||||
| 著者 ローマ字 | ||||||
| 値 | Noguchi, Tomohiro | |||||
| 著者 ローマ字 | ||||||
| 値 | Takakusaki, Kaoru | |||||
| 著者 ローマ字 | ||||||
| 値 | Kashiwayanagi, Makoto | |||||
| 書誌情報 |
Biological and pharmaceutical bulletin 巻 37, 号 12, p. 1907-1912, 発行日 2014-01-01 |
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| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 0918-6158 | |||||
| DOI | ||||||
| 関連タイプ | isIdenticalTo | |||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | 10.1248/bpb.b14-00413 | |||||
| 識別番号 その他 | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | PMID:25451840 | |||||
| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | TRPV2, a member of the transient receptor potential family, has been isolated as a capsaicin-receptor homolog and is thought to respond to noxious heat. Here we show that TRPV2 mRNA is predominantly expressed in the subpopulation of olfactory sensory neurons (OSNs). We carried out histochemical analyses of TRPV2 and insulin-like growth factor-I receptor (IGF-IR) using in situ hybridization and immunofluorescence in the adult olfactory system. In olfactory mucosa, intensive TRPV2 immunostaining was observed at the olfactory axon bundles but not at the soma. TRPV2-positive labeling was preferentially found in the olfactory nerve layer in the olfactory bulb (OB). Furthermore, we demonstrated that a positive signal for IGF-IR mRNA was detected in OSNs expressing TRPV2 mRNA. In embryonic stages, TRPV2 immunoreactivity was observed on axon bundles of developing OSNs in the nasal region starting from 12.5 d of gestation and through fetal development. Observations in this study suggest that TRPV2 coupled with IGF-IR localizes to growing olfactory axons in the OSNs. | |||||
| 注記 | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | 出版社版 | |||||
| 資源タイプ | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | text | |||||
| 著者版フラグ | ||||||
| 出版タイプ | VoR | |||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
| フォーマット | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | application/pdf | |||||
| ID(XooNIps) | ||||||
| 値 | 25451840 | |||||
| 閲覧数(XooNIps) | ||||||
| 値 | 695 | |||||
| ダウンロード数(XooNIps) | ||||||
| 値 | 683 | |||||
