{"created":"2023-06-19T11:24:29.571799+00:00","id":5219,"links":{},"metadata":{"_buckets":{"deposit":"f9e149cc-58c0-4247-98a0-134e012d0576"},"_deposit":{"created_by":1,"id":"5219","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"5219"},"status":"published"},"_oai":{"id":"oai:asahikawa-med.repo.nii.ac.jp:00005219","sets":["7","7:24"]},"author_link":["16237","16240","16239","16238"],"item_5_biblio_info_21":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2014-01-01","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"12","bibliographicPageEnd":"1912","bibliographicPageStart":"1907","bibliographicVolumeNumber":"37","bibliographic_titles":[{"bibliographic_title":"Biological and pharmaceutical bulletin"}]}]},"item_5_description_28":{"attribute_name":"識別番号 その他","attribute_value_mlt":[{"subitem_description":"PMID:25451840","subitem_description_type":"Other"}]},"item_5_description_33":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"TRPV2, a member of the transient receptor potential family, has been isolated as a capsaicin-receptor homolog and is thought to respond to noxious heat. Here we show that TRPV2 mRNA is predominantly expressed in the subpopulation of olfactory sensory neurons (OSNs). We carried out histochemical analyses of TRPV2 and insulin-like growth factor-I receptor (IGF-IR) using in situ hybridization and immunofluorescence in the adult olfactory system. In olfactory mucosa, intensive TRPV2 immunostaining was observed at the olfactory axon bundles but not at the soma. TRPV2-positive labeling was preferentially found in the olfactory nerve layer in the olfactory bulb (OB). Furthermore, we demonstrated that a positive signal for IGF-IR mRNA was detected in OSNs expressing TRPV2 mRNA. In embryonic stages, TRPV2 immunoreactivity was observed on axon bundles of developing OSNs in the nasal region starting from 12.5 d of gestation and through fetal development. Observations in this study suggest that TRPV2 coupled with IGF-IR localizes to growing olfactory axons in the OSNs.","subitem_description_type":"Abstract"}]},"item_5_description_36":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"出版社版","subitem_description_type":"Other"}]},"item_5_description_37":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"subitem_description":"text","subitem_description_type":"Other"}]},"item_5_description_41":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_5_relation_24":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"10.1248/bpb.b14-00413","subitem_relation_type_select":"DOI"}}]},"item_5_source_id_22":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0918-6158","subitem_source_identifier_type":"ISSN"}]},"item_5_text_44":{"attribute_name":"ID(XooNIps)","attribute_value_mlt":[{"subitem_text_value":"25451840"}]},"item_5_text_54":{"attribute_name":"閲覧数(XooNIps)","attribute_value_mlt":[{"subitem_text_value":"695"}]},"item_5_text_55":{"attribute_name":"ダウンロード数(XooNIps)","attribute_value_mlt":[{"subitem_text_value":"683"}]},"item_5_text_7":{"attribute_name":"著者 ローマ字","attribute_value_mlt":[{"subitem_text_value":"Matsui, Hitoshi"},{"subitem_text_value":"Noguchi, Tomohiro"},{"subitem_text_value":"Takakusaki, Kaoru"},{"subitem_text_value":"Kashiwayanagi, Makoto"}]},"item_5_version_type_38":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"松井, 等"},{"creatorName":"マツイ, ヒトシ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"16237","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"野口, 智弘"},{"creatorName":"ノグチ, トモヒロ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"16238","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"高草木, 薫"},{"creatorName":"タカクサキ, カオル","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"16239","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"柏柳, 誠"},{"creatorName":"カシワヤナギ, マコト","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"16240","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2021-07-06"}],"displaytype":"detail","filename":"6118.pdf","filesize":[{"value":"1.6 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"6118.pdf","url":"https://asahikawa-med.repo.nii.ac.jp/record/5219/files/6118.pdf"},"version_id":"f89a6e21-d0f3-482b-80ea-79662191769f"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"olfactory neuron","subitem_subject_scheme":"Other"},{"subitem_subject":"olfactory epithelium","subitem_subject_scheme":"Other"},{"subitem_subject":"olfactory bulb","subitem_subject_scheme":"Other"},{"subitem_subject":"insulin-like growth factor-I receptor","subitem_subject_scheme":"Other"},{"subitem_subject":"transient receptor potential V2","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Co-localization of TRPV2 and insulin-like growth factor-I receptor in olfactory neurons in adult and fetal mouse.","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Co-localization of TRPV2 and insulin-like growth factor-I receptor in olfactory neurons in adult and fetal mouse."}]},"item_type_id":"5","owner":"1","path":["6","7","24"],"pubdate":{"attribute_name":"公開日","attribute_value":"2015-05-19"},"publish_date":"2015-05-19","publish_status":"0","recid":"5219","relation_version_is_last":true,"title":["Co-localization of TRPV2 and insulin-like growth factor-I receptor in olfactory neurons in adult and fetal mouse."],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-06-19T12:26:59.114881+00:00"}