WEKO3
-
RootNode
アイテム
Tryptophan-Restriction Diets Help to Maintain L-Tryptophan Homeostasis in Tryptophan 2,3-Dioxygenase Knockout Mice
https://asahikawa-med.repo.nii.ac.jp/records/4515
https://asahikawa-med.repo.nii.ac.jp/records/4515152b7b8c-ef1b-4ada-9669-83ce6ed46b2b
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
5305.pdf (652.0 kB)
|
|
| Item type | 学術雑誌論文 / Journal Article_02(1) | |||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 公開日 | 2013-07-01 | |||||||||||||||
| タイトル | ||||||||||||||||
| タイトル | Tryptophan-Restriction Diets Help to Maintain L-Tryptophan Homeostasis in Tryptophan 2,3-Dioxygenase Knockout Mice | |||||||||||||||
| 言語 | en | |||||||||||||||
| 言語 | ||||||||||||||||
| 言語 | eng | |||||||||||||||
| キーワード | ||||||||||||||||
| 主題Scheme | Other | |||||||||||||||
| キーワード | tryptophan, TDO-deficient mice, 0.06% L-Trp diet, wild-type mice | |||||||||||||||
| 資源タイプ | ||||||||||||||||
| 資源タイプ | journal article | |||||||||||||||
| 著者 |
Maeta, Akihiro
× Maeta, Akihiro
× Fukuwatari, Tsutomu
× Funakoshi, Hiroshi
× Nakamura, Toshikazu
× Shibata, Katsumi
|
|||||||||||||||
| 書誌情報 |
International Journal of Tryptophan Research p. 1-11, 発行日 2013-06-01 |
|||||||||||||||
| ISSN | ||||||||||||||||
| 収録物識別子タイプ | EISSN | |||||||||||||||
| 収録物識別子 | 1178-6469 | |||||||||||||||
| 抄録 | ||||||||||||||||
| 内容記述タイプ | Abstract | |||||||||||||||
| 内容記述 | We hypothesized that the requirements of essential nutrients are dependent upon catabolic abilities. Mice lacking L-tryptophan 2,3-dioxygenase (TDO) are available. The body concentration of L-tryptophan (L-Trp) has been reported to be higher in TDO-deficient mice than in wild-type (WT) mice. We examined the requirement of an appropriate L-Trp level for TDO-deficient mice using several biomarkers. TDO-deficient mice were fed a 10% amino-acid mixture diet containing 0.06%, 0.08%, and 0.17% L-Trp. WT mice fed a 0.17% Trp diet (standard diet) were used as control mice. The concentrations of L-Trp and its metabolites via serotonin were higher in TDO-deficient mice fed the 0.17% L-Trp diet than in WT mice fed the standard diet, but the concentrations were almost identical between TDO-deficient mice fed the 0.06% L-Trp diet and WT mice fed the standard diet. Therefore, as hypothesized, requirements of essential nutrients are dependent on catabolic abilities. | |||||||||||||||
| 言語 | en | |||||||||||||||
| 注記 | ||||||||||||||||
| 内容記述タイプ | Other | |||||||||||||||
| 注記 | Publisher | |||||||||||||||
| 資源タイプ | ||||||||||||||||
| 内容記述タイプ | Other | |||||||||||||||
| 資源タイプ | text | |||||||||||||||
| 著者版フラグ | ||||||||||||||||
| 出版タイプ | VoR | |||||||||||||||
| フォーマット | ||||||||||||||||
| 内容記述タイプ | Other | |||||||||||||||
| 内容記述 | application/pdf | |||||||||||||||
| ID(XooNIps) | ||||||||||||||||
| IJTR2013-6-1 | ||||||||||||||||
| 閲覧数(XooNIps) | ||||||||||||||||
| ダウンロード数(XooNIps) | ||||||||||||||||
| 683 | ||||||||||||||||
Share
Cite as
Maeta, Akihiro, Fukuwatari, Tsutomu, Funakoshi, Hiroshi, Nakamura, Toshikazu, Shibata, Katsumi, n.d., Tryptophan-Restriction Diets Help to Maintain L-Tryptophan Homeostasis in Tryptophan 2,3-Dioxygenase Knockout Mice: 1–11 p.
Loading...
