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Combination of Antihypertensive Therapy in The Elderly, Multicenter Investigation (CAMUI) Trial
https://asahikawa-med.repo.nii.ac.jp/records/4001
https://asahikawa-med.repo.nii.ac.jp/records/40011c6eac70-6449-419c-94cc-ad40e3820c62
| 名前 / ファイル | ライセンス | アクション |
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| Item type | 学術雑誌論文 / Journal Article_02(1) | |||||||||||||
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| 公開日 | 2012-08-13 | |||||||||||||
| タイトル | ||||||||||||||
| タイトル | Combination of Antihypertensive Therapy in The Elderly, Multicenter Investigation (CAMUI) Trial | |||||||||||||
| 言語 | en | |||||||||||||
| 言語 | ||||||||||||||
| 言語 | eng | |||||||||||||
| キーワード | ||||||||||||||
| 主題Scheme | Other | |||||||||||||
| キーワード | Antihypertensive agents | |||||||||||||
| キーワード | ||||||||||||||
| 主題Scheme | Other | |||||||||||||
| キーワード | Combination therapy | |||||||||||||
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| 主題Scheme | Other | |||||||||||||
| キーワード | Cognitive function | |||||||||||||
| 資源タイプ | ||||||||||||||
| 資源タイプ | journal article | |||||||||||||
| 著者 |
佐藤, 伸之
× 佐藤, 伸之
× Saijo, Yasuaki
× Hasebe, Naoyuki
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| 書誌情報 |
International Heart Journal 巻 53, 号 4, p. 244-248, 発行日 2012-08-01 |
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| ISSN | ||||||||||||||
| 収録物識別子タイプ | PISSN | |||||||||||||
| 収録物識別子 | 1349-2365 | |||||||||||||
| 抄録 | ||||||||||||||
| 内容記述タイプ | Abstract | |||||||||||||
| 内容記述 | Angiotensin receptor blockers (ARBs) with calcium channel blockers (CCBs) or diuretics are a widely used combination therapy for hypertensive patients. The present study aimed to determine which combination was better for elderly hypertension patients aged ≧ 65 years. We designed a multicentre, randomized, open-label, parallel comparison study. Hypertensive outpatients aged ≧ 65 years who did not achieve the target blood pressure (BP < 140/90 mmHg) with usual dosages of ARBs were randomly assigned to switch treatment to losartan 50 mg/hydrochlorothiazide 12.5 mg or amlodipine 5 mg in addition to ARBs. The primary endpoint was a change in the systolic blood pressure (SBP) and diastolic blood pressure (DBP) after the 3-month treatment period, while secondary endpoints were changes in the BP, albuminuria, laboratory values, and cognitive function with the mini-mental state examination (MMSE) at baseline and after one year. The results from the CAMUI trial should provide new evidence for selecting optimal combination therapies for elderly hypertensive patients. | |||||||||||||
| 言語 | en | |||||||||||||
| 注記 | ||||||||||||||
| 内容記述タイプ | Other | |||||||||||||
| 注記 | 雑誌掲載版 J-STAGE掲載版使用 https://www.jstage.jst.go.jp/browse/-char/ja |
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| 資源タイプ | ||||||||||||||
| 内容記述タイプ | Other | |||||||||||||
| 資源タイプ | text | |||||||||||||
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| 出版タイプ | VoR | |||||||||||||
| フォーマット | ||||||||||||||
| 内容記述タイプ | Other | |||||||||||||
| 内容記述 | application/pdf | |||||||||||||
| ID(XooNIps) | ||||||||||||||
| Inter-H-J-53-4-244 | ||||||||||||||
| 閲覧数(XooNIps) | ||||||||||||||
| ダウンロード数(XooNIps) | ||||||||||||||
| 584 | ||||||||||||||