{"created":"2023-06-19T11:23:27.637151+00:00","id":4001,"links":{},"metadata":{"_buckets":{"deposit":"d1c4aa6c-b59e-43d5-b718-4bf25cf2e229"},"_deposit":{"created_by":3,"id":"4001","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"4001"},"status":"published"},"_oai":{"id":"oai:asahikawa-med.repo.nii.ac.jp:00004001","sets":["7","7:23"]},"author_link":["12060","12061","12062"],"item_5_biblio_info_21":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2012-08-01","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"4","bibliographicPageEnd":"248","bibliographicPageStart":"244","bibliographicVolumeNumber":"53","bibliographic_titles":[{"bibliographic_title":"International Heart Journal"}]}]},"item_5_description_33":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Angiotensin receptor blockers (ARBs) with calcium channel blockers (CCBs) or diuretics are a widely used combination therapy for hypertensive patients. The present study aimed to determine which combination was better for elderly hypertension patients aged ≧ 65 years.  We designed a multicentre, randomized, open-label, parallel comparison study. Hypertensive outpatients aged ≧ 65 years who did not achieve the target blood pressure (BP < 140/90 mmHg) with usual dosages of ARBs were randomly assigned to switch treatment to losartan 50 mg/hydrochlorothiazide 12.5 mg or amlodipine 5 mg in addition to ARBs. The primary endpoint was a change in the systolic blood pressure (SBP) and diastolic blood pressure (DBP) after the 3-month treatment period, while secondary endpoints were changes in the BP, albuminuria, laboratory values, and cognitive function with the mini-mental state examination (MMSE) at baseline and after one year. The results from the CAMUI trial should provide new evidence for selecting optimal combination therapies for elderly hypertensive patients.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_5_description_36":{"attribute_name":"注記","attribute_value_mlt":[{"subitem_description":"雑誌掲載版 J-STAGE掲載版使用\nhttps://www.jstage.jst.go.jp/browse/-char/ja","subitem_description_type":"Other"}]},"item_5_description_37":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"subitem_description":"text","subitem_description_type":"Other"}]},"item_5_description_41":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_5_source_id_22":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1349-2365","subitem_source_identifier_type":"PISSN"}]},"item_5_text_44":{"attribute_name":"ID(XooNIps)","attribute_value_mlt":[{"subitem_text_value":"Inter-H-J-53-4-244"}]},"item_5_text_54":{"attribute_name":"閲覧数(XooNIps)","attribute_value_mlt":[{"subitem_text_value":"1199"}]},"item_5_text_55":{"attribute_name":"ダウンロード数(XooNIps)","attribute_value_mlt":[{"subitem_text_value":"584"}]},"item_5_version_type_38":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"佐藤, 伸之","creatorNameLang":"ja"},{"creatorName":"サトウ, ノブユキ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"12060","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Saijo, Yasuaki","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"12061","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Hasebe, Naoyuki","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"12062","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2021-07-06"}],"displaytype":"detail","filename":"4746.pdf","filesize":[{"value":"1.9 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"4746.pdf","url":"https://asahikawa-med.repo.nii.ac.jp/record/4001/files/4746.pdf"},"version_id":"b99e35e4-0090-4f02-b6a4-cfc10496825e"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Antihypertensive agents","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Combination therapy","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Cognitive function","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Combination of Antihypertensive Therapy in The Elderly, Multicenter Investigation (CAMUI) Trial","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Combination of Antihypertensive Therapy in The Elderly, Multicenter Investigation (CAMUI) Trial","subitem_title_language":"en"}]},"item_type_id":"5","owner":"3","path":["6","7","23"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2012-08-13"},"publish_date":"2012-08-13","publish_status":"0","recid":"4001","relation_version_is_last":true,"title":["Combination of Antihypertensive Therapy in The Elderly, Multicenter Investigation (CAMUI) Trial"],"weko_creator_id":"3","weko_shared_id":-1},"updated":"2024-07-26T09:03:30.009253+00:00"}