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Novel perspectives in probiotic treatment : the efficacy and unveiled mechanisms of the physiological functions
https://asahikawa-med.repo.nii.ac.jp/records/3987
https://asahikawa-med.repo.nii.ac.jp/records/39874315177f-52ac-4a98-a3ab-d149b81f3574
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
4545.pdf (251.1 kB)
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| Item type | 学術雑誌論文 / Journal Article_02(1) | |||||||||||
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| 公開日 | 2012-05-17 | |||||||||||
| タイトル | ||||||||||||
| タイトル | Novel perspectives in probiotic treatment : the efficacy and unveiled mechanisms of the physiological functions | |||||||||||
| 言語 | en | |||||||||||
| 言語 | ||||||||||||
| 言語 | eng | |||||||||||
| 資源タイプ | ||||||||||||
| 資源タイプ | journal article | |||||||||||
| 著者 |
藤谷, 幹浩
× 藤谷, 幹浩
× Kohgo, Yutaka
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| 書誌情報 |
Clinical Journal of Gastroenterology 巻 3, 号 3, p. 117-127, 発行日 2010-06-01 |
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| 収録物識別子タイプ | PISSN | |||||||||||
| 収録物識別子 | 1865-7257 | |||||||||||
| DOI | ||||||||||||
| 識別子タイプ | DOI | |||||||||||
| 関連識別子 | 10.1007/s12328-010-0154-0 | |||||||||||
| リンクURL | ||||||||||||
| 内容記述タイプ | Other | |||||||||||
| 内容記述 | The original publication is available at www.springerlink.com. | The original publication is available at www.springerlink.com. | |||||||||||
| 抄録 | ||||||||||||
| 内容記述タイプ | Abstract | |||||||||||
| 内容記述 | Probiotics are defined as “live microorganisms which confer a health benefit on the host” when administered in adequate amounts, and have potential effects for maintaining intestinal development, nutrition, and treating intestinal inflammations, functional disorders, and other extra-intestinal diseases. Although the benefits of probiotics for human health were first noted over 100 years ago, the analysis of probiotic functions began in earnest only 20 years ago. Probiotics, such as some strains of Lactobacillus, Bifidobacterium, Escherichia coli, and Bacillus subtilis, inhibit the growth of pathogenic bacteria, induce competitive effects for the adherent of pathogenic bacteria and their toxins to intestinal epithelia, induce cytoprotective heat shock proteins, enhance the intestinal barrier function, and modulate the host immune responses. The crosstalk between the host and the probiotics appears to be mediated by bacteria-derived effectors, which can be sensed with multiple systems, including the Toll-like receptors and cell membrane transporters. Future analyses will identify more probiotic-derived effectors, the recognition mechanisms of these effectors, and the subsequent changes of the intestinal epithelia and immune cells for each probiotic treatment. For clinical use, a procedure that objectively evaluates the ability of each probiotic effect will help establish a standard for choosing the most valuable strain and its proper dose for each individual patient. | |||||||||||
| 言語 | en | |||||||||||
| 注記 | ||||||||||||
| 内容記述タイプ | Other | |||||||||||
| 注記 | http://dx.doi.org/10.1007/s12328-010-0154-0 | |||||||||||
| 資源タイプ | ||||||||||||
| 内容記述タイプ | Other | |||||||||||
| 資源タイプ | text | |||||||||||
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| 出版タイプ | AM | |||||||||||
| フォーマット | ||||||||||||
| 内容記述タイプ | Other | |||||||||||
| 内容記述 | application/pdf | |||||||||||
| ID(XooNIps) | ||||||||||||
| 8301 | ||||||||||||
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| ダウンロード数(XooNIps) | ||||||||||||
| 769 | ||||||||||||
