| Item type |
学術雑誌論文 / Journal Article_02(1) |
| 公開日 |
2008-04-28 |
| タイトル |
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|
タイトル |
Nasopharyngeal colonization with nontypeable Haemophilus influenzae and recurrent otitis media |
|
言語 |
en |
| 言語 |
|
|
言語 |
eng |
| 資源タイプ |
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|
資源タイプ |
journal article |
| 著者 |
原渕, 保明
Faden, H
Yamanaka, N
Duffy, L
Wolf, J
Krystofik, D
Williamsville, T
|
| 著者 ローマ字 |
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|
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Harabuchi, Yasuaki |
| 書誌情報 |
Journal of infectious diseases
巻 170,
号 4,
p. 862-866,
発行日 1994-01-01
|
| ISSN |
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収録物識別子タイプ |
ISSN |
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収録物識別子 |
0022-1899 |
| DOI |
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関連タイプ |
isIdenticalTo |
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|
識別子タイプ |
DOI |
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|
関連識別子 |
10.1093/infdis/170.4.862 |
| リンクURL |
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内容記述タイプ |
Other |
|
内容記述 |
http://www.ncbi.nlm.nih.gov/pubmed/7930728 | http://www.ncbi.nlm.nih.gov/pubmed/7930728 |
| 抄録 |
|
|
内容記述タイプ |
Abstract |
|
内容記述 |
The relationship between nasopharyngeal colonization with nontypeable H. influenzae and recurrent otitis media was assessed in 157 children followed prospectively from birth through 12 months of age. Forty-nine (31%) became colonized. Nasopharyngeal secretory IgA (sIgA) reactive with the P6 outer membrane protein was detected in all colonized children. Reduction or elimination of the organism was associated with a better mucosal immune response (560 +/- 864 units/ng/mL of sIgA) than was persistence in the nasopharynx (121 +/- 81; P = .04). Forty colonized children (82%) and 61 noncolonized children (56%) developed otitis media (P = .004); colonized children were four times more likely to be classified as otitis prone (P = .003). The frequency of otitis media episodes was directly related to the frequency of colonization (r = .42, P < .01). These results demonstrate a strong relationship between nasopharyngeal colonization patterns and otitis media. The mucosal immune response may be important in elimination of potential pathogens from the respiratory tract. |
| 注記 |
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|
内容記述タイプ |
Other |
|
注記 |
University of Chicago Press, Harabuchi, Y. ; Faden, H. ; Yamanaka, N. ; Duffy, L. ; Wolf, J. ; Krystofik, D. ; Williamsville, T.,Journal of Infectious Diseases, 170(4), 1994, 862-866.
\npublisher |
| 資源タイプ |
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|
内容記述タイプ |
Other |
|
資源タイプ |
text |
| 著者版フラグ |
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出版タイプ |
VoR |
| フォーマット |
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内容記述タイプ |
Other |
|
内容記述 |
application/pdf |
| ID(XooNIps) |
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7930728 |
| 閲覧数(XooNIps) |
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| ダウンロード数(XooNIps) |
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|
2152 |
983.pdf (2.7 MB)
