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Evaluation of purified Taenia solium glycoproteins and recombinant antigens in the serologic detection of human and swine cysticercosis

https://asahikawa-med.repo.nii.ac.jp/records/661
https://asahikawa-med.repo.nii.ac.jp/records/661
8888637b-3f62-49ff-9946-b7c000f3a863
名前 / ファイル ライセンス アクション
834.pdf 834.pdf (876.2 kB)
Item type 学術雑誌論文 / Journal Article_02(1)
公開日 2008-01-08
タイトル
タイトル Evaluation of purified Taenia solium glycoproteins and recombinant antigens in the serologic detection of human and swine cysticercosis
言語 en
言語
言語 eng
資源タイプ
資源タイプ journal article
著者 伊藤, 亮

× 伊藤, 亮

伊藤, 亮

ja-Kana イトウ, アキラ

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Sato, MO

× Sato, MO

Sato, MO

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Sako, Y

× Sako, Y

Sako, Y

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Nakao, M

× Nakao, M

Nakao, M

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Yamasaki, H

× Yamasaki, H

Yamasaki, H

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Nakaya, K

× Nakaya, K

Nakaya, K

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著者 ローマ字
Ito, Akira
書誌情報 Journal of Infectious Diseases

巻 194, 号 12, p. 1783-1790, 発行日 2006-12-01
ISSN
収録物識別子タイプ ISSN
収録物識別子 0022-1899
DOI
関連タイプ isIdenticalTo
識別子タイプ DOI
関連識別子 10.1086/509262
リンクURL
内容記述タイプ Other
内容記述 http://www.ncbi.nlm.nih.gov/pubmed?term=Evaluation%20of%20purified%20Taenia%20solium%20glycoproteins%20and%20recombinant%20antigens%20in%20the%20serologic%20detection%20of%20human%20and%20swine%20cysticercosis | http://www.ncbi.nlm.nih.gov/pubmed?term=Evaluation%20of%20purified%20Taenia%20solium%20glycoproteins%20and%20recombinant%20antigens%20in%20the%20serologic%20detection%20of%20human%20and%20swine%20cysticercosis
抄録
内容記述タイプ Abstract
内容記述 Cysticercosis caused by infection with embryonated eggs of Taenia solium is an important cause of neurological disease worldwide. On the basis of mitochondrial DNA analysis, T. solium is divided into 2 (African/American and Asian) genotypes. Glycoproteins (GPs) in cyst fluid purified from the 2 genotypes of T. solium were characterized and compared with the recombinant chimeric T. solium-Ag1V1/Ag2 protein (Rec-Ag1V1/Ag2) as serodiagnostic antigens. Immunoblot analysis revealed that banding patterns of GPs differed between the 2 genotypes because of posttranslation modification, especially glycosylation. The comparison of native GPs with Rec-Ag1V1/Ag2 by enzyme-linked immunosorbent assay demonstrated that there was no statistical difference in sensitivity. In addition, the conservation of the genes encoding Ag1V1 and Ag2 in T. solium worldwide was verified. These results indicate that Rec-Ag1V1/Ag2 has great potential for usefulness in serodiagnosis as an alternative to native antigens.
注記
内容記述タイプ Other
注記 University of Chicago Press, Sato, Marcello Otake ; Sako, Yasuhito ; Nakao, Minoru ; Yamasaki, Hiroshi ; Nakaya, Kazuhiro ; Ito, Akira, Journal of Infectious Diseases, 194(12), 2006, 1783-1790.
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内容記述タイプ Other
資源タイプ text
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出版タイプ VoR
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内容記述 application/pdf
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17109353
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Cite as

伊藤, 亮, Sato, MO, Sako, Y, Nakao, M, Yamasaki, H, Nakaya, K, n.d., Evaluation of purified Taenia solium glycoproteins and recombinant antigens in the serologic detection of human and swine cysticercosis: 1783–1790 p.

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