| Item type |
学術雑誌論文 / Journal Article_02(1) |
| 公開日 |
2007-12-03 |
| タイトル |
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タイトル |
Echinococcus multilocularis: developmental stage-specific expression of Antigen B 8-kDa-subunits |
|
言語 |
en |
| 言語 |
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|
言語 |
eng |
| 資源タイプ |
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資源タイプ |
journal article |
| 著者 |
伊藤, 亮
Mamuti, W
Sako, Y
Xiao, N
Nakaya, K
Nakao, M
Yamasaki, H
Lightowlers, MW
Craig, PS
|
| 著者 ローマ字 |
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Ito, Akira |
| 書誌情報 |
Experimental Parasitology
巻 113,
号 2,
p. 75-82,
発行日 2006-06-01
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| ISSN |
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収録物識別子タイプ |
ISSN |
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収録物識別子 |
0014-4894 |
| DOI |
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関連タイプ |
isVersionOf |
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識別子タイプ |
DOI |
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|
関連識別子 |
10.1016/j.exppara.2005.12.007 |
| リンクURL |
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内容記述タイプ |
Other |
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内容記述 |
http://www.sciencedirect.com/science/journal/00144894 | http://www.sciencedirect.com/science/journal/00144894 |
| 抄録 |
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内容記述タイプ |
Abstract |
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内容記述 |
Antigen B (AgB) initially found in hydatid cyst fluid of Echinococcus granulosus is a polymeric lipoprotein of 160 kDa, and is an aggregate of several different but homologous small proteins with approximately 8 kDa. Four genes encoding these 8-kDa-subunits have been identified from E. granulosus. In this study we isolated five genes encoding 8-kDa-subunits of AgB from Echinococcus multilocularis. Sequence comparison of isolated cDNA clones demonstrated that one of these five clones was completely identical to EmAgB8/1 which had been isolated previously by our group, and three of them were 94.5, 90.8, and 91.9% homologous to E. granulosus antigen B 8-kDa subunit genes, EgAgB8/2, EgAgB8/3, and EgAgB8/4, respectively. The remaining clone shared 51–58% homology with the nucleotide sequences of AgB genes. Gene-specific RT-PCR and Western blot analyses revealed that these genes were expressed in a developmentally regulated manner in E. multilocularis vesicles, protoscoleces, and immature adult worms. Possible functions of different expression manners are also discussed. |
| 注記 |
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内容記述タイプ |
Other |
|
注記 |
Academic Press, Mamuti, Wulamu ; Sako, Yasuhito ; Xiao, Ning ; Nakaya, Kazuhiro ; Nakao, Minoru ; Yamasaki, Hiroshi ; Lightowlers, Marshall W. ; Craig, Philip S. ; Ito, Akira, Experimental Parasitology, 113(2), 2006, 75-82
\nauthor |
| 資源タイプ |
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内容記述タイプ |
Other |
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資源タイプ |
text |
| 著者版フラグ |
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出版タイプ |
AM |
| フォーマット |
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内容記述タイプ |
Other |
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内容記述 |
application/pdf |
| ID(XooNIps) |
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16458295 |
| 閲覧数(XooNIps) |
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| ダウンロード数(XooNIps) |
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1719 |
807.pdf (655.6 kB)
