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Echinococcus multilocularis: developmental stage-specific expression of Antigen B 8-kDa-subunits
https://asahikawa-med.repo.nii.ac.jp/records/646
https://asahikawa-med.repo.nii.ac.jp/records/64683803bbf-2183-47f3-a492-03a168a2d665
名前 / ファイル | ライセンス | アクション |
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807.pdf (655.6 kB)
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Item type | 学術雑誌論文 / Journal Article_02(1) | |||||
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公開日 | 2007-12-03 | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | Echinococcus multilocularis: developmental stage-specific expression of Antigen B 8-kDa-subunits | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ | journal article | |||||
著者 |
伊藤, 亮
× 伊藤, 亮× Mamuti, W× Sako, Y× Xiao, N× Nakaya, K× Nakao, M× Yamasaki, H× Lightowlers, MW× Craig, PS |
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著者 ローマ字 | ||||||
Ito, Akira | ||||||
書誌情報 |
Experimental Parasitology 巻 113, 号 2, p. 75-82, 発行日 2006-06-01 |
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ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 0014-4894 | |||||
DOI | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | DOI | |||||
関連識別子 | 10.1016/j.exppara.2005.12.007 | |||||
リンクURL | ||||||
内容記述タイプ | Other | |||||
内容記述 | http://www.sciencedirect.com/science/journal/00144894 | http://www.sciencedirect.com/science/journal/00144894 | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Antigen B (AgB) initially found in hydatid cyst fluid of Echinococcus granulosus is a polymeric lipoprotein of 160 kDa, and is an aggregate of several different but homologous small proteins with approximately 8 kDa. Four genes encoding these 8-kDa-subunits have been identified from E. granulosus. In this study we isolated five genes encoding 8-kDa-subunits of AgB from Echinococcus multilocularis. Sequence comparison of isolated cDNA clones demonstrated that one of these five clones was completely identical to EmAgB8/1 which had been isolated previously by our group, and three of them were 94.5, 90.8, and 91.9% homologous to E. granulosus antigen B 8-kDa subunit genes, EgAgB8/2, EgAgB8/3, and EgAgB8/4, respectively. The remaining clone shared 51–58% homology with the nucleotide sequences of AgB genes. Gene-specific RT-PCR and Western blot analyses revealed that these genes were expressed in a developmentally regulated manner in E. multilocularis vesicles, protoscoleces, and immature adult worms. Possible functions of different expression manners are also discussed. | |||||
注記 | ||||||
内容記述タイプ | Other | |||||
注記 | Academic Press, Mamuti, Wulamu ; Sako, Yasuhito ; Xiao, Ning ; Nakaya, Kazuhiro ; Nakao, Minoru ; Yamasaki, Hiroshi ; Lightowlers, Marshall W. ; Craig, Philip S. ; Ito, Akira, Experimental Parasitology, 113(2), 2006, 75-82 \nauthor |
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資源タイプ | ||||||
内容記述タイプ | Other | |||||
資源タイプ | text | |||||
著者版フラグ | ||||||
出版タイプ | AM | |||||
フォーマット | ||||||
内容記述タイプ | Other | |||||
内容記述 | application/pdf | |||||
ID(XooNIps) | ||||||
16458295 | ||||||
閲覧数(XooNIps) | ||||||
2525 | ||||||
ダウンロード数(XooNIps) | ||||||
1719 |