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Pyrazine analogues from wolf urine induced unlearned fear in rats
https://asahikawa-med.repo.nii.ac.jp/records/5920
https://asahikawa-med.repo.nii.ac.jp/records/592055e59b4d-5ff2-41dc-a35d-f2a7ef1897ce
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
7035.pdf (1.1 MB)
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| Item type | 学術雑誌論文 / Journal Article_02(1) | |||||||||||||||||
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| 公開日 | 2018-07-26 | |||||||||||||||||
| タイトル | ||||||||||||||||||
| タイトル | Pyrazine analogues from wolf urine induced unlearned fear in rats | |||||||||||||||||
| 言語 | ||||||||||||||||||
| 言語 | eng | |||||||||||||||||
| キーワード | ||||||||||||||||||
| 主題Scheme | Other | |||||||||||||||||
| キーワード | Neuroscience | |||||||||||||||||
| 資源タイプ | ||||||||||||||||||
| 資源タイプ | journal article | |||||||||||||||||
| 著者 |
柏柳, 誠
× 柏柳, 誠
× 宮園, 貞治
× 長田, 和実
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| 著者 ローマ字 | ||||||||||||||||||
| Kashiwayanagi, Makoto | ||||||||||||||||||
| 著者 ローマ字 | ||||||||||||||||||
| Miyazono, Sadaharu | ||||||||||||||||||
| 著者 ローマ字 | ||||||||||||||||||
| Osada, Kazumi | ||||||||||||||||||
| 書誌情報 |
Heliyon 巻 3, 号 8, p. e00391, 発行日 2017-08-01 |
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| ISSN | ||||||||||||||||||
| 収録物識別子タイプ | ISSN | |||||||||||||||||
| 収録物識別子 | 2405-8440 | |||||||||||||||||
| DOI | ||||||||||||||||||
| 関連タイプ | isIdenticalTo | |||||||||||||||||
| 識別子タイプ | DOI | |||||||||||||||||
| 関連識別子 | 10.1016/j.heliyon.2017.e00391 | |||||||||||||||||
| 識別番号 その他 | ||||||||||||||||||
| 内容記述タイプ | Other | |||||||||||||||||
| 内容記述 | PMID：28920093 | |||||||||||||||||
| 抄録 | ||||||||||||||||||
| 内容記述タイプ | Abstract | |||||||||||||||||
| 内容記述 | Urine excreted from the common grey wolf (Canis lupus) contains a kairomone, inducing fear-related behaviors in various mammals. Numerous fear-inducing substances activate neurons at the main and/or accessory olfactory bulb (AOB), medial and central amygdala, and hypothalamus. Our previous study showed that the mixture of pyrazine analogues (P-mix) contained in wolf urine induced avoidance and fear-related behaviors in laboratory mice and Hokkaido deer (Cervus nippon yesoensis), a species native to Japan. Exposure to wolf urine or P-mix induced expression of Fos, a marker of neuronal excitation, in the AOB of mice. In the present study, we explored the effects of P-mix on fear-related behaviors and Fos-expression in rats. Exposure to P-mix induced avoidance and immobilization in rats, while that to a mixture of i-amyl acetate, linalool and R(+)-limonene (O-mix), which generate floral and fruity odors, induced avoidance but not immobilization. P-mix but not O-mix increased Fos-immunoreactivity of the AOB, medial and central amygdala, and hypothalamus of rats. The present results suggest that P-mix odor induces unlearned fear-related behaviors in rats. | |||||||||||||||||
| 注記 | ||||||||||||||||||
| 内容記述タイプ | Other | |||||||||||||||||
| 注記 | This is an open access article distributed under the terms of the Creative Commons Attribution-Noncommercial License 4.0 (CCBY-NC), | |||||||||||||||||
| 資源タイプ | ||||||||||||||||||
| 内容記述タイプ | Other | |||||||||||||||||
| 資源タイプ | text | |||||||||||||||||
| 著者版フラグ | ||||||||||||||||||
| 出版タイプ | VoR | |||||||||||||||||
| フォーマット | ||||||||||||||||||
| 内容記述タイプ | Other | |||||||||||||||||
| 内容記述 | application/pdf | |||||||||||||||||
| ID(XooNIps) | ||||||||||||||||||
| 28920093 | ||||||||||||||||||
| 閲覧数(XooNIps) | ||||||||||||||||||
| ダウンロード数(XooNIps) | ||||||||||||||||||
| 910 | ||||||||||||||||||
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Cite as
柏柳, 誠, 宮園, 貞治, 長田, 和実, n.d., Pyrazine analogues from wolf urine induced unlearned fear in rats: e00391– p.
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