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Inverted gastric adenocarcinoma of fundic gland mucosa type colliding with well differentiated adenocarcinoma: A case report
https://asahikawa-med.repo.nii.ac.jp/records/5911
https://asahikawa-med.repo.nii.ac.jp/records/59117bad4916-2a34-407e-9af7-2f6debe56865
名前 / ファイル | ライセンス | アクション |
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Item type | 学術雑誌論文 / Journal Article_02(1) | |||||
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公開日 | 2018-06-28 | |||||
タイトル | ||||||
タイトル | Inverted gastric adenocarcinoma of fundic gland mucosa type colliding with well differentiated adenocarcinoma: A case report | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
高橋, 慶太郎
× 高橋, 慶太郎× 藤谷, 幹浩× 市原, 真× 盛一, 健太郎× 奥村, 利勝 |
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著者 ローマ字 | ||||||
値 | Takahashi, Keitaro | |||||
著者 ローマ字 | ||||||
値 | Fujiya, Mikihiro | |||||
著者 ローマ字 | ||||||
値 | Ichihara, Shin | |||||
著者 ローマ字 | ||||||
値 | Moriichi, Kentaro | |||||
著者 ローマ字 | ||||||
値 | Okumura, Toshikatsu | |||||
書誌情報 |
Medicine 巻 96, 号 23, p. e7080, 発行日 2017-06-01 |
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ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 0025-7974 | |||||
DOI | ||||||
関連タイプ | isIdenticalTo | |||||
識別子タイプ | DOI | |||||
関連識別子 | 10.1097/MD.0000000000007080 | |||||
識別番号 その他 | ||||||
内容記述タイプ | Other | |||||
内容記述 | PMID:28591047 | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | RATIONALE: \nGastric adenocarcinoma of fundic gland mucosa type (GA-FGM) is a rare tumor composed of atypical cells with differentiation toward the fundic gland as well as the foveolar epithelium. Including our case, only 9 cases of GA-FGMs were reported from 2010 to 2016. CONCERNS OF THE PATIENT: \nAn 87-year-old man was referred to our institution for endoscopic resection of a gastric lesion. The tumor was classified as type 0-I + IIa according to the Paris classification. Magnifying endoscopy with narrow band imaging (ME-NBI) revealed different structures of crypts and vessels among the components, illustrating the collision of 2 types of gastric cancer. INTERVENTIONS: \nWe performed endoscopic submucosal dissection and successfully removed the tumor en bloc. OUTCOMES: \nThe histological findings differed markedly between the 0-I lesion and the 0-IIa lesion. The superficial part of the 0-I lesion consisted of a papillary structure, and the deeper part consisted of a tubular structure that showed inverted downward growth to the submucosal layer with the lamina muscularis mucosae. Immunohistochemically, the superficial part of the 0-I lesion was positive for MUC5AC, which had differentiated to foveolar epithelium. The deeper part was positive for pepsinogen-I and MUC6, which had differentiated to fundic gland. The 0-I lesion was diagnosed as gastric phenotype of adenocarcinoma differentiated to fundic gland mucosa with upward growth in the superficial part and downward growth in the deeper part. The 0-IIa lesion was composed of a tubular structure positive for MUC2, and it was diagnosed as an intestinal phenotype of well differentiated adenocarcinoma. The boundary was clear, and no transitional tissue was observed between the 0-I and 0-IIa lesions, suggesting that the 0-I + IIa lesion was a gastric collision tumor of GA-FGM and well differentiated adenocarcinoma. LESSONS: \nWe herein report the first case of inverted GA-FGM colliding with well differentiated adenocarcinoma. ME-NBI can be used to diagnose GA-FGM even if the lesion collides with other types of adenocarcinoma. |
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注記 | ||||||
内容記述タイプ | Other | |||||
内容記述 | This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY) | |||||
資源タイプ | ||||||
内容記述タイプ | Other | |||||
内容記述 | text | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
フォーマット | ||||||
内容記述タイプ | Other | |||||
内容記述 | application/pdf | |||||
ID(XooNIps) | ||||||
値 | 28591047 | |||||
閲覧数(XooNIps) | ||||||
値 | 359 | |||||
ダウンロード数(XooNIps) | ||||||
値 | 193 |