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Inverted gastric adenocarcinoma of fundic gland mucosa type colliding with well differentiated adenocarcinoma: A case report
https://asahikawa-med.repo.nii.ac.jp/records/5911
https://asahikawa-med.repo.nii.ac.jp/records/59117bad4916-2a34-407e-9af7-2f6debe56865
| 名前 / ファイル | ライセンス | アクション |
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7022.pdf (1.0 MB)
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| Item type | 学術雑誌論文 / Journal Article_02(1) | |||||||||||||||||||||||||
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| 公開日 | 2018-06-28 | |||||||||||||||||||||||||
| タイトル | ||||||||||||||||||||||||||
| タイトル | Inverted gastric adenocarcinoma of fundic gland mucosa type colliding with well differentiated adenocarcinoma: A case report | |||||||||||||||||||||||||
| 言語 | ||||||||||||||||||||||||||
| 言語 | eng | |||||||||||||||||||||||||
| 資源タイプ | ||||||||||||||||||||||||||
| 資源タイプ | journal article | |||||||||||||||||||||||||
| 著者 |
高橋, 慶太郎
× 高橋, 慶太郎
× 藤谷, 幹浩
× 市原, 真
× 盛一, 健太郎
× 奥村, 利勝
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| 著者 ローマ字 | ||||||||||||||||||||||||||
| Takahashi, Keitaro | ||||||||||||||||||||||||||
| 著者 ローマ字 | ||||||||||||||||||||||||||
| Fujiya, Mikihiro | ||||||||||||||||||||||||||
| 著者 ローマ字 | ||||||||||||||||||||||||||
| Ichihara, Shin | ||||||||||||||||||||||||||
| 著者 ローマ字 | ||||||||||||||||||||||||||
| Moriichi, Kentaro | ||||||||||||||||||||||||||
| 著者 ローマ字 | ||||||||||||||||||||||||||
| Okumura, Toshikatsu | ||||||||||||||||||||||||||
| 書誌情報 |
Medicine 巻 96, 号 23, p. e7080, 発行日 2017-06-01 |
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| 収録物識別子タイプ | ISSN | |||||||||||||||||||||||||
| 収録物識別子 | 0025-7974 | |||||||||||||||||||||||||
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| 関連タイプ | isIdenticalTo | |||||||||||||||||||||||||
| 識別子タイプ | DOI | |||||||||||||||||||||||||
| 関連識別子 | 10.1097/MD.0000000000007080 | |||||||||||||||||||||||||
| 識別番号 その他 | ||||||||||||||||||||||||||
| 内容記述タイプ | Other | |||||||||||||||||||||||||
| 内容記述 | PMID：28591047 | |||||||||||||||||||||||||
| 抄録 | ||||||||||||||||||||||||||
| 内容記述タイプ | Abstract | |||||||||||||||||||||||||
| 内容記述 | RATIONALE: \nGastric adenocarcinoma of fundic gland mucosa type (GA-FGM) is a rare tumor composed of atypical cells with differentiation toward the fundic gland as well as the foveolar epithelium. Including our case, only 9 cases of GA-FGMs were reported from 2010 to 2016. CONCERNS OF THE PATIENT: \nAn 87-year-old man was referred to our institution for endoscopic resection of a gastric lesion. The tumor was classified as type 0-I + IIa according to the Paris classification. Magnifying endoscopy with narrow band imaging (ME-NBI) revealed different structures of crypts and vessels among the components, illustrating the collision of 2 types of gastric cancer. INTERVENTIONS: \nWe performed endoscopic submucosal dissection and successfully removed the tumor en bloc. OUTCOMES: \nThe histological findings differed markedly between the 0-I lesion and the 0-IIa lesion. The superficial part of the 0-I lesion consisted of a papillary structure, and the deeper part consisted of a tubular structure that showed inverted downward growth to the submucosal layer with the lamina muscularis mucosae. Immunohistochemically, the superficial part of the 0-I lesion was positive for MUC5AC, which had differentiated to foveolar epithelium. The deeper part was positive for pepsinogen-I and MUC6, which had differentiated to fundic gland. The 0-I lesion was diagnosed as gastric phenotype of adenocarcinoma differentiated to fundic gland mucosa with upward growth in the superficial part and downward growth in the deeper part. The 0-IIa lesion was composed of a tubular structure positive for MUC2, and it was diagnosed as an intestinal phenotype of well differentiated adenocarcinoma. The boundary was clear, and no transitional tissue was observed between the 0-I and 0-IIa lesions, suggesting that the 0-I + IIa lesion was a gastric collision tumor of GA-FGM and well differentiated adenocarcinoma. LESSONS: \nWe herein report the first case of inverted GA-FGM colliding with well differentiated adenocarcinoma. ME-NBI can be used to diagnose GA-FGM even if the lesion collides with other types of adenocarcinoma. |
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| 注記 | ||||||||||||||||||||||||||
| 内容記述タイプ | Other | |||||||||||||||||||||||||
| 注記 | This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY) | |||||||||||||||||||||||||
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| 内容記述タイプ | Other | |||||||||||||||||||||||||
| 資源タイプ | text | |||||||||||||||||||||||||
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| 出版タイプ | VoR | |||||||||||||||||||||||||
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| 内容記述タイプ | Other | |||||||||||||||||||||||||
| 内容記述 | application/pdf | |||||||||||||||||||||||||
| ID(XooNIps) | ||||||||||||||||||||||||||
| 28591047 | ||||||||||||||||||||||||||
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| 193 | ||||||||||||||||||||||||||
