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Effects of Habitual Cigarette Smoking on Retinal Circulation in Patients With Type 2 Diabetes

https://asahikawa-med.repo.nii.ac.jp/records/5727
https://asahikawa-med.repo.nii.ac.jp/records/5727
5cb5a6cc-a3c2-4c03-ab17-4126166457a6
名前 / ファイル ライセンス アクション
6793.pdf 6793.pdf (373.7 kB)
Item type 学術雑誌論文 / Journal Article_02(1)
公開日 2017-09-20
タイトル
タイトル Effects of Habitual Cigarette Smoking on Retinal Circulation in Patients With Type 2 Diabetes
言語
言語 eng
資源タイプ
資源タイプ journal article
著者 大前, 恒明

× 大前, 恒明

大前, 恒明

ja-Kana オオマエ, ツネアキ

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長岡, 泰司

× 長岡, 泰司

長岡, 泰司

ja-Kana ナガオカ, タイジ

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著者 ローマ字
Omae, Tsuneaki
著者 ローマ字
Nagaoka, Taiji
書誌情報 Investigative Ophthalmology and Visual Science

巻 57, 号 3, p. 1345-1351, 発行日 2016-05-01
ISSN
収録物識別子タイプ ISSN
収録物識別子 1552-5783
DOI
関連タイプ isIdenticalTo
識別子タイプ DOI
関連識別子 10.1167/iovs.15-18813.
識別番号 その他
内容記述タイプ Other
内容記述 PMID:27002294
抄録
内容記述タイプ Abstract
内容記述 PURPOSE:
\nTo examine the long-term effects of cigarette smoking on retinal circulation in patients with type 2 diabetes.
METHODS:
\nSeventy-four patients with type 2 diabetes mellitus and minimal (no or mild nonproliferative) diabetic retinopathy (DR) were evaluated. These patients with type 2 diabetes were divided into three groups based on their smoking history: current smokers (n = 19), past smokers (n = 20), and never smoked (n = 35). The retinal circulatory parameters were measured with laser Doppler velocimetry and were compared among the groups.
RESULTS:
\nThere were significant decreases in the retinal blood flow (RBF; 8.9 ± 2.9 vs. 11.6 ± 3.1 μL/min, P = 0.009) with decreased blood velocity (V; 29.6 ± 6.8 vs. 37.8 ± 9.0 mm/s, P = 0.003) but no difference in the vessel diameter (D; 112.0 ± 11.9 vs. 113.7 ± 8.6 μm, P = 0.57) in the current smokers compared with those who never smoked. There were no differences in the RBF, blood V, and vessel D in the past smokers compared with those who never smoked and current smokers. Multiple regression analysis showed that the creatinine level was correlated negatively with the RBF and that current smoking was significantly and independent correlated with decreased RBF.
CONCLUSIONS:
\nOur results indicated that the blood V and RBF in the retinal arterioles may decrease in patients with type 2 diabetes who are chronic smokers, suggesting that chronic smoking may be associated with decreased RBF, probably via lower blood V in the retinal arterioles in early-phase DR.
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資源タイプ text
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出版タイプ VoR
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内容記述タイプ Other
内容記述 application/pdf
ID(XooNIps)
27002294
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537
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Cite as

大前, 恒明, 長岡, 泰司, n.d., Effects of Habitual Cigarette Smoking on Retinal Circulation in Patients With Type 2 Diabetes: 1345–1351 p.

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