| Item type |
学術雑誌論文 / Journal Article_02(1) |
| 公開日 |
2017-09-12 |
| タイトル |
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タイトル |
Genetics of the Pig Tapeworm in Madagascar Reveal a History of Human Dispersal and Colonization |
| 言語 |
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言語 |
eng |
| 資源タイプ |
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資源タイプ |
journal article |
| 著者 |
柳田, 哲矢
Jean-François, Carod
迫, 康仁
中尾, 稔
Eric, P. Hoberg
伊藤, 亮
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| 著者 ローマ字 |
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Yanagida, Tetsuya |
| 著者 ローマ字 |
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| 著者 ローマ字 |
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Sako, Yasuhito |
| 著者 ローマ字 |
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Nakao, Minoru |
| 著者 ローマ字 |
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| 著者 ローマ字 |
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Ito, Akira |
| 書誌情報 |
PLoS One
巻 9,
号 10,
p. e109002,
発行日 2014-10-01
|
| ISSN |
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収録物識別子タイプ |
ISSN |
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収録物識別子 |
1932-6203 |
| DOI |
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関連タイプ |
isIdenticalTo |
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識別子タイプ |
DOI |
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関連識別子 |
10.1371/journal.pone.0109002 |
| 識別番号 その他 |
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内容記述タイプ |
Other |
|
内容記述 |
PMID：25329310 |
| 抄録 |
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内容記述タイプ |
Abstract |
|
内容記述 |
An intricate history of human dispersal and geographic colonization has strongly affected the distribution of human pathogens. The pig tapeworm Taenia solium occurs throughout the world as the causative agent of cysticercosis, one of the most serious neglected tropical diseases. Discrete genetic lineages of T. solium in Asia and Africa/Latin America are geographically disjunct; only in Madagascar are they sympatric. Linguistic, archaeological and genetic evidence has indicated that the people in Madagascar have mixed ancestry from Island Southeast Asia and East Africa. Hence, anthropogenic introduction of the tapeworm from Southeast Asia and Africa had been postulated. This study shows that the major mitochondrial haplotype of T. solium in Madagascar is closely related to those from the Indian Subcontinent. Parasitological evidence presented here, and human genetics previously reported, support the hypothesis of an Indian influence on Malagasy culture coinciding with periods of early human migration onto the island. We also found evidence of nuclear-mitochondrial discordance in single tapeworms, indicating unexpected cross-fertilization between the two lineages of T. solium. Analyses of genetic and geographic populations of T. solium in Madagascar will shed light on apparently rapid evolution of this organism driven by recent (<2,000 yr) human migrations, following tens of thousands of years of geographic isolation. |
| 注記 |
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内容記述タイプ |
Other |
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注記 |
This is an open-access article |
| 資源タイプ |
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内容記述タイプ |
Other |
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資源タイプ |
text |
| 著者版フラグ |
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出版タイプ |
VoR |
| フォーマット |
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内容記述タイプ |
Other |
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内容記述 |
application/pdf |
| ID(XooNIps) |
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25329310 |
| 閲覧数(XooNIps) |
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| ダウンロード数(XooNIps) |
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1141 |
6783.pdf (1.1 MB)
