| Item type |
学術雑誌論文 / Journal Article_02(1) |
| 公開日 |
2017-08-18 |
| タイトル |
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|
タイトル |
Clinicopathological Study of Epithelial Metaplastic Breast Cancer |
| 言語 |
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|
言語 |
eng |
| キーワード |
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主題Scheme |
Other |
|
キーワード |
Breast Cancer |
| キーワード |
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主題Scheme |
Other |
|
キーワード |
Metaplastic Breast Cancer |
| キーワード |
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|
主題Scheme |
Other |
|
キーワード |
Triple Negative Type |
| キーワード |
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主題Scheme |
Other |
|
キーワード |
Epithelial-Mesenchymal Transition |
| 資源タイプ |
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|
資源タイプ |
journal article |
| 著者 |
北田, 正博
安田, 俊輔
高橋, 奈七
岡崎, 智
石橋, 圭
林, 諭史
|
| 著者 ローマ字 |
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|
|
Kitada, Masahiro |
| 著者 ローマ字 |
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|
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Yasuda, Shunsuke |
| 著者 ローマ字 |
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Takahashi, Nana |
| 著者 ローマ字 |
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Okazaki, Satoshi |
| 著者 ローマ字 |
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|
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Ishibashi, Kei |
| 著者 ローマ字 |
|
|
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Hayashi, Satoshi |
| 書誌情報 |
Journal of Cancer Therapy
巻 7,
号 13,
p. 1039-1044,
発行日 2016-12-01
|
| ISSN |
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収録物識別子タイプ |
ISSN |
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収録物識別子 |
2151-1934 |
| DOI |
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関連タイプ |
isIdenticalTo |
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識別子タイプ |
DOI |
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関連識別子 |
10.4236/jct.2016.713100 |
| 抄録 |
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内容記述タイプ |
Abstract |
|
内容記述 |
Introduction: Metaplastic breast cancer (MBC) is a rare pathological type with an incidence rate of not more than 1%, and has been reported to be often detected after its progression and highly malignant with a high proportion of triple negative type tumors, with poor outcomes as compared to IDC [1] [2] [3]. We analyzed clinicopathological characteristics of patients who underwent surgery for epithelial MBC at our department. Patients and Methods: From January 2000 to March 2014, a total of 2120 patients underwent surgery for breast cancer, and MBC was diagnosed in 15 of these patients. Fourteen of the 15 had epithelial MBC and were included in this study. The present study compared clinopathological characteristics of MBC with those of IDC of triple negative type (TN type group) and IDC of non-triple negative type (IDC group). Results: Breast conserving surgery was performed in 7 patients with MBC (50%), a proportion clearly lower than the 64.3% in the IDC group. The mean tumor size was 3.8 cm, which was greater than the 2.13 cm in the TN type group and the 1.7 cm in the IDC group. About nuclear grade, the proportion of grade III was 57.1%, markedly higher than the 38.6% in the TN type group and the 12.6% in the IDC group. All patients were estrogen receptor (ER) and progesterone receptor (PgR) negative; 11 patients were TN type tumors and 3 were HER2 type. Conclusion: We studied patients who underwent surgery for epithelial MBC. The examined cases showed clinopathological characteristics of the disease, including large tumors with a highly malignant nature at the initial detection, higher Ki-67 levels, ER and PgR negativity (all cases), mostly TN type, and a high recurrence rate. |
| 資源タイプ |
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|
内容記述タイプ |
Other |
|
資源タイプ |
text |
| 著者版フラグ |
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|
出版タイプ |
VoR |
| フォーマット |
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|
内容記述タイプ |
Other |
|
内容記述 |
application/pdf |
| ID(XooNIps) |
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|
2017081801 |
| 閲覧数(XooNIps) |
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| ダウンロード数(XooNIps) |
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|
747 |
6766.pdf (407.4 kB)
