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Clinical Impact and Implication of Real-Time Oscillation Analysis for Language Mapping.

https://asahikawa-med.repo.nii.ac.jp/records/5660
https://asahikawa-med.repo.nii.ac.jp/records/5660
bfd7a9f3-f1ae-4016-bbc5-78f2d89eca8e
名前 / ファイル ライセンス アクション
6710.pdf 6710.pdf (370.1 kB)
Item type 学位論文 / Thesis or Dissertation_02(1)
公開日 2017-04-26
タイトル
タイトル Clinical Impact and Implication of Real-Time Oscillation Analysis for Language Mapping.
言語 en
言語
言語 jpn
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_46ec
資源タイプ thesis
著者 小川, 博司

× 小川, 博司

ja 小川, 博司

ja-Kana オガワ, ヒロシ

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著者 ローマ字
Ogawa, Hiroshi
書誌情報 World neurosurgery

号 97, p. 123-131, 発行日 2017-01-01
ISSN
収録物識別子タイプ ISSN
収録物識別子 1878-8750
DOI
識別子タイプ DOI
関連識別子 10.1016/j.wneu.2016.09.071.
識別番号 その他
内容記述タイプ Other
内容記述 PMID:27686506
学位授与番号
学位授与番号 10107A510
学位授与年月日
学位授与年月日 2017-03-24
学位名
学位名 博士(医学)
学位授与機関
学位授与機関名 旭川医科大学
抄録
内容記述タイプ Abstract
内容記述 BACKGROUND:
\nWe developed a functional brain analysis system that enabled us to perform real-time task-related electrocorticography (ECoG) and evaluated its potential in clinical practice. We hypothesized that high gamma activity (HGA) mapping would provide better spatial and temporal resolution with high signal-to-noise ratios.
METHODS:
\nSeven awake craniotomy patients were evaluated. ECoG was recorded during language tasks using subdural grids, and HGA (60-170 Hz) maps were obtained in real time. The patients also underwent electrocortical stimulation (ECS) mapping to validate the suspected functional locations on HGA mapping. The results were compared and calculated to assess the sensitivity and specificity of HGA mapping. For reference, bedside HGA-ECS mapping was performed in 5 epilepsy patients.
RESULTS:
\nHGA mapping demonstrated functional brain areas in real time and was comparable with ECS mapping. Sensitivity and specificity for the language area were 90.1% ± 11.2% and 90.0% ± 4.2%, respectively. Most HGA-positive areas were consistent with ECS-positive regions in both groups, and there were no statistical between-group differences.
CONCLUSIONS:
\nAlthough this study included a small number of subjects, it showed real-time HGA mapping with the same setting and tasks under different conditions. This study demonstrates the clinical feasibility of real-time HGA mapping. Real-time HGA mapping enabled simple and rapid detection of language functional areas in awake craniotomy. The mapping results were highly accurate, although the mapping environment was noisy. Further studies of HGA mapping may provide the potential to elaborate complex brain functions and networks.
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内容記述タイプ Other
内容記述 application/pdf
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内容記述タイプ Other
内容記述 application/pdf
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