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Clinical Impact and Implication of Real-Time Oscillation Analysis for Language Mapping.
https://asahikawa-med.repo.nii.ac.jp/records/5660
https://asahikawa-med.repo.nii.ac.jp/records/5660bfd7a9f3-f1ae-4016-bbc5-78f2d89eca8e
名前 / ファイル | ライセンス | アクション |
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Item type | 学位論文 / Thesis or Dissertation_02(1) | |||||||||
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公開日 | 2017-04-26 | |||||||||
タイトル | ||||||||||
タイトル | Clinical Impact and Implication of Real-Time Oscillation Analysis for Language Mapping. | |||||||||
言語 | en | |||||||||
言語 | ||||||||||
言語 | jpn | |||||||||
資源タイプ | ||||||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_46ec | |||||||||
資源タイプ | thesis | |||||||||
著者 |
小川, 博司
× 小川, 博司
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著者 ローマ字 | ||||||||||
Ogawa, Hiroshi | ||||||||||
書誌情報 |
World neurosurgery 号 97, p. 123-131, 発行日 2017-01-01 |
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ISSN | ||||||||||
収録物識別子タイプ | ISSN | |||||||||
収録物識別子 | 1878-8750 | |||||||||
DOI | ||||||||||
識別子タイプ | DOI | |||||||||
関連識別子 | 10.1016/j.wneu.2016.09.071. | |||||||||
識別番号 その他 | ||||||||||
内容記述タイプ | Other | |||||||||
内容記述 | PMID:27686506 | |||||||||
学位授与番号 | ||||||||||
学位授与番号 | 10107A510 | |||||||||
学位授与年月日 | ||||||||||
学位授与年月日 | 2017-03-24 | |||||||||
学位名 | ||||||||||
学位名 | 博士(医学) | |||||||||
学位授与機関 | ||||||||||
学位授与機関名 | 旭川医科大学 | |||||||||
抄録 | ||||||||||
内容記述タイプ | Abstract | |||||||||
内容記述 | BACKGROUND: \nWe developed a functional brain analysis system that enabled us to perform real-time task-related electrocorticography (ECoG) and evaluated its potential in clinical practice. We hypothesized that high gamma activity (HGA) mapping would provide better spatial and temporal resolution with high signal-to-noise ratios. METHODS: \nSeven awake craniotomy patients were evaluated. ECoG was recorded during language tasks using subdural grids, and HGA (60-170 Hz) maps were obtained in real time. The patients also underwent electrocortical stimulation (ECS) mapping to validate the suspected functional locations on HGA mapping. The results were compared and calculated to assess the sensitivity and specificity of HGA mapping. For reference, bedside HGA-ECS mapping was performed in 5 epilepsy patients. RESULTS: \nHGA mapping demonstrated functional brain areas in real time and was comparable with ECS mapping. Sensitivity and specificity for the language area were 90.1% ± 11.2% and 90.0% ± 4.2%, respectively. Most HGA-positive areas were consistent with ECS-positive regions in both groups, and there were no statistical between-group differences. CONCLUSIONS: \nAlthough this study included a small number of subjects, it showed real-time HGA mapping with the same setting and tasks under different conditions. This study demonstrates the clinical feasibility of real-time HGA mapping. Real-time HGA mapping enabled simple and rapid detection of language functional areas in awake craniotomy. The mapping results were highly accurate, although the mapping environment was noisy. Further studies of HGA mapping may provide the potential to elaborate complex brain functions and networks. |
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内容記述タイプ | Other | |||||||||
内容記述 | application/pdf | |||||||||
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内容記述タイプ | Other | |||||||||
内容記述 | application/pdf |