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Identification and Characterization of a Novel Human Collectin CL-K1
https://asahikawa-med.repo.nii.ac.jp/records/5516
https://asahikawa-med.repo.nii.ac.jp/records/551634087ab6-82d6-41c6-8cae-173bab546067
名前 / ファイル | ライセンス | アクション |
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6527.pdf (2.0 MB)
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Item type | 学術雑誌論文 / Journal Article_02(1) | |||||
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公開日 | 2016-08-17 | |||||
タイトル | ||||||
タイトル | Identification and Characterization of a Novel Human Collectin CL-K1 | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ | journal article | |||||
著者 |
芥子, 宏行
× 芥子, 宏行× Sakamoto, Takashi× 河合, 高生× 加藤, 剛志× Jang, Seong-Jae× 本村, 亘× 吉崎, 隆之× 福田, 光子× 小山, 聡× 福澤, 純× 福應, 温× 吉田, 逸朗× 鈴木, 定彦× 若宮, 伸隆 |
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著者 ローマ字 | ||||||
Keshi, Hiroyuki | ||||||
著者 ローマ字 | ||||||
著者 ローマ字 | ||||||
Kawai, Takao | ||||||
著者 ローマ字 | ||||||
Katoh, Tsuyoshi | ||||||
著者 ローマ字 | ||||||
著者 ローマ字 | ||||||
Motomura, Wataru | ||||||
著者 ローマ字 | ||||||
Yoshizaki, Takayuki | ||||||
著者 ローマ字 | ||||||
Fukuda, Mitsuko | ||||||
著者 ローマ字 | ||||||
Koyama, Satoshi | ||||||
著者 ローマ字 | ||||||
Fukuzawa, Jun | ||||||
著者 ローマ字 | ||||||
Fukuoh, Atsushi | ||||||
著者 ローマ字 | ||||||
Yoshida, Itsuro | ||||||
著者 ローマ字 | ||||||
Suzuki, Yasuhiko | ||||||
著者 ローマ字 | ||||||
Wakamiya, Nobutaka | ||||||
書誌情報 |
Microbiology and Immunology 巻 50, 号 12, p. 1001-1013, 発行日 2006-12-01 |
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ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 0385-5600 | |||||
DOI | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | DOI | |||||
関連識別子 | 10.1111/j.1348-0421.2006.tb03868.x | |||||
識別番号 その他 | ||||||
内容記述タイプ | Other | |||||
内容記述 | PMID:17179669 | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Collectins are a family of C-type lectins with two characteristic structures, collagen like domains and carbohydrate recognition domains. They recognize carbohydrate antigens on microorganisms and act as host-defense. Here we report the cloning and characterization of a novel collectin CL-K1. RT-PCR analyses showed CL-K1 mRNA is present in all organs. The deduced amino acid sequence and the data from immunostaining of CL-K1 cDNA expressing CHO cells revealed that CL-K1 is expressed as a secreted protein. CL-K1 is found in blood by immunoblotting and partial amino acid analyses. CL-K1 showed Ca(2+)-dependent sugar binding activity of fucose and weakly mannose but not N-acetyl-galactosamine, N-acetyl-glucosamine, or maltose, though mannose-binding lectin (MBL) containing similar amino acid motif. CL-K1 can recognize specially several bacterial saccharides due to specific sugar-binding character. Elucidation of the role of two ancestor collectins of CL-K1 and CL-L1 could lead to see the biological function of collectin family. | |||||
資源タイプ | ||||||
内容記述タイプ | Other | |||||
資源タイプ | text | |||||
著者版フラグ | ||||||
出版タイプ | AM | |||||
フォーマット | ||||||
内容記述タイプ | Other | |||||
内容記述 | application/pdf | |||||
ID(XooNIps) | ||||||
17179669 | ||||||
閲覧数(XooNIps) | ||||||
544 | ||||||
ダウンロード数(XooNIps) | ||||||
562 |