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Changes in retinal blood flow in patients with macular edema secondary to branch retinal vein occlusion before and after intravitreal injection of bevacizumab.

https://asahikawa-med.repo.nii.ac.jp/records/5282
https://asahikawa-med.repo.nii.ac.jp/records/5282
ad80cbcd-637d-4961-97df-63c901ca3ec7
名前 / ファイル ライセンス アクション
6194.pdf 6194.pdf (213.8 kB)
Item type 学術雑誌論文 / Journal Article_02(1)
公開日 2015-09-07
タイトル
タイトル Changes in retinal blood flow in patients with macular edema secondary to branch retinal vein occlusion before and after intravitreal injection of bevacizumab.
言語
言語 eng
資源タイプ
資源タイプ journal article
著者 長岡, 泰司

× 長岡, 泰司

長岡, 泰司

ja-Kana ナガオカ, タイジ

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十川, 健司

× 十川, 健司

十川, 健司

ja-Kana ソガワ, ケンジ

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吉田, 晃敏

× 吉田, 晃敏

吉田, 晃敏

ja-Kana ヨシダ, アキトシ

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著者 ローマ字
Nagaoka, Taiji
著者 ローマ字
Sogawa, Kenji
著者 ローマ字
Yoshida, Akitoshi
書誌情報 Retina.

巻 34, 号 10, p. 2037-2043, 発行日 2014-10-01
ISSN
収録物識別子タイプ ISSN
収録物識別子 0275-004X
DOI
関連タイプ isVersionOf
識別子タイプ DOI
関連識別子 10.1097/IAE.0000000000000172.
識別番号 その他
内容記述タイプ Other
内容記述 PMID:24896136
抄録
内容記述タイプ Abstract
内容記述 PURPOSE:
\nTo investigate the effect of intravitreal bevacizumab (IVB) injections for macular edema secondary to acute branch retinal vein occlusion on the retinal microcirculation.
METHODS:
\nThe study was a prospective, interventional case series. Central macular thickness using spectral-domain optical coherence tomography and retinal blood flow (RBF) in untreated eyes with macular edema secondary to acute branch retinal vein occlusion in occluded (V1) and opposite venules in affected eyes (V2) and the equivalent venules in contralateral eyes (V3), using laser Doppler velocimetry during follow-up and after IVB injection, were measured.
RESULTS:
\nIn 33 eyes with acute branch retinal vein occlusion of <2 months of duration at the first visit, changes in the retinal microcirculation for 1 month was observed; the macular edema improved spontaneously, and the RBF was unchanged in 15 of 33 eyes, and the RBF increased by 23.3% in 18 eyes with persistent macular edema. Twenty-four eyes received an IVB injection (1.25 mg per 0.05 mL). The RBF did not change significantly during follow-up. In 8 of 24 eyes (33%) with improved macular edema 3 months after the treatment, the average RBF values before injection were significantly higher compared with that of eyes with recurrent edema.
CONCLUSION:
\nOne IVB injection might have little effect on the retinal microcirculation in patients with macular edema secondary to acute branch retinal vein occlusion at least 3 months after the injection. However, the increased RBF in the occluded venules before injection might be associated with improved macular edema after the IVB injection.
注記
内容記述タイプ Other
注記 著者最終版
資源タイプ
内容記述タイプ Other
資源タイプ text
著者版フラグ
出版タイプ AM
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内容記述タイプ Other
内容記述 application/pdf
ID(XooNIps)
24896136
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ダウンロード数(XooNIps)
459
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