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A Quantitative Evaluation of Hepatic Uptake on I-131 Whole-Body Scintigraphy for Postablative Therapy of Thyroid Carcinoma.
https://asahikawa-med.repo.nii.ac.jp/records/5280
https://asahikawa-med.repo.nii.ac.jp/records/52805c85523d-25de-4ff6-ac14-4830e5310cd8
名前 / ファイル | ライセンス | アクション |
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6221.pdf (304.6 kB)
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Item type | 学術雑誌論文 / Journal Article_02(1) | |||||
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公開日 | 2015-10-22 | |||||
タイトル | ||||||
タイトル | A Quantitative Evaluation of Hepatic Uptake on I-131 Whole-Body Scintigraphy for Postablative Therapy of Thyroid Carcinoma. | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
中山, 理寛
× 中山, 理寛× 沖崎, 貴琢× 坂口, 美喜× 石戸谷, 俊太× 宇野, 貴寛× 佐藤, 順一× 高橋, 康二 |
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著者 ローマ字 | ||||||
値 | Nakayama, Michihiro | |||||
著者 ローマ字 | ||||||
値 | Okizaki, Atsutaka | |||||
著者 ローマ字 | ||||||
値 | Sakaguchi, Miki | |||||
著者 ローマ字 | ||||||
値 | Ishitoya, Shunta | |||||
著者 ローマ字 | ||||||
値 | Uno, Takahiro | |||||
著者 ローマ字 | ||||||
値 | Sato, Junichi | |||||
著者 ローマ字 | ||||||
値 | Takahashi, Koji | |||||
書誌情報 |
Medicine (Baltimore). 巻 94, 号 28, 発行日 2015-07-01 |
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DOI | ||||||
関連タイプ | isIdenticalTo | |||||
識別子タイプ | DOI | |||||
関連識別子 | 10.1097/MD.0000000000001191. | |||||
リンクURL | ||||||
内容記述タイプ | Other | |||||
内容記述 | http://journals.lww.com/md-journal/pages/articleviewer.aspx?year=2015&issue=07030&article=00036&type=abstract | http://journals.lww.com/md-journal/pages/articleviewer.aspx?year=2015&issue=07030&article=00036&type=abstract | |||||
識別番号 その他 | ||||||
内容記述タイプ | Other | |||||
内容記述 | PMID:26181567 | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | This study aimed to determine clinical association between quantitative hepatic uptake on postablative whole-body scan (WBS) with differentiated thyroid cancer (DTC) prognosis. We analyzed 541 scans of 216 DTC patients who were divided into 3 groups based on radioactive iodine (I-131) WBS uptake and clinical follow-up: group 1 (completion of ablation), group 2 (abnormal uptake in the cervical region), and group 3 (abnormal uptake with distant metastases). For each group, we calculated the ratio of I-131 WBS hepatic uptake (H) to cranial uptake as background (B); this ratio was defined as H/B. Furthermore, we made a distinction between group 1, as having completed radioactive iodine therapy (RIT) (CR), and group 2 and 3, as requiring subsequent RIT (RR). The average H/B scores were 1.34 (median, 1.36; range 1.00-2.1) for group 1; 1.89 (median, 1.75; range 1.41-4.20) for group 2; and 2.09 (median, 1.90; range 1.50-4.32) for group 3. Bonferroni multiple comparisons revealed significant differences in H/B among these groups. The H/B of group 1 was significantly smaller than that of other 2 groups (P < 0.0001). The precise cutoff value of H/B for therapeutic effect was ≤1.5. Moreover, 159 of 160 scans in the CR and 375 of 381 patients in the RR were correctly diagnosed using this cutoff value in the final outcome of RIT, yielding a sensitivity, specificity, positive predictive value, and negative predictive value of 99.4%, 98.4%, 99.7%, and 96.3%, respectively. Increased hepatic uptake of I-131 on WBS may predict disease-related progression. | |||||
注記 | ||||||
内容記述タイプ | Other | |||||
内容記述 | CC BY 4.0 オープンアクセス論文 |
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資源タイプ | ||||||
内容記述タイプ | Other | |||||
内容記述 | text | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
フォーマット | ||||||
内容記述タイプ | Other | |||||
内容記述 | application/pdf | |||||
ID(XooNIps) | ||||||
値 | 26181567 | |||||
閲覧数(XooNIps) | ||||||
値 | 812 | |||||
ダウンロード数(XooNIps) | ||||||
値 | 985 |