| Item type |
学術雑誌論文 / Journal Article_02(1) |
| 公開日 |
2014-04-22 |
| タイトル |
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|
タイトル |
Successful Control of Disseminated Intravascular Coagulation by Recombinant Thrombomodulin during Arsenic Trioxide Treatment in Relapsed Patient with Acute Promyelocytic Leukemia. |
| 言語 |
|
|
言語 |
eng |
| 資源タイプ |
|
|
資源タイプ |
journal article |
| 著者 |
進藤, 基博
Ikuta, Katsuya
Addo, Linda
Ito, Satoshi
Fujiya, Mikihiro
Torimoto, Yoshihiro
Kohgo, Yutaka
|
| 著者 ローマ字 |
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Shindo, Motohiro |
| 著者 ローマ字 |
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|
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Ikuta, Katsuya |
| 著者 ローマ字 |
|
|
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Addo, Linda |
| 著者 ローマ字 |
|
|
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Ito, Satoshi |
| 著者 ローマ字 |
|
|
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Fujiya, Mikihiro |
| 著者 ローマ字 |
|
|
|
Torimoto, Yoshihiro |
| 著者 ローマ字 |
|
|
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Kohgo, Yutaka |
| 書誌情報 |
Case reports in hematology
巻 2012,
p. 908196,
発行日 2012-01-01
|
| ISSN |
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|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
2090-6579 |
| 識別番号 その他 |
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内容記述タイプ |
Other |
|
内容記述 |
PMID:23008787 |
| 抄録 |
|
|
内容記述タイプ |
Abstract |
|
内容記述 |
Disseminated intravascular coagulation (DIC) frequently occurs in patients with acute promyelocytic leukemia (APL). With the induction of therapy in APL using all-trans retinoic acid (ATRA), DIC can be controlled in most cases as ATRA usually shows immediate improvement of the APL. However, arsenic trioxide (ATO) which has been used for the treatment of relapse in APL patients has shown to take time to suppress APL cells, therefore the control of DIC in APL with ATO treatment is a major problem. Recently, the recombinant soluble thrombomodulin fragment has received a lot of attention as the novel drug for the treatment of DIC with high efficacy. Here, we present a relapsed patient with APL in whom DIC was successfully and safely controlled by rTM during treatment with ATO. |
| 注記 |
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内容記述タイプ |
Other |
|
注記 |
Publisher |
| 資源タイプ |
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内容記述タイプ |
Other |
|
資源タイプ |
text |
| フォーマット |
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内容記述タイプ |
Other |
|
内容記述 |
application/pdf |
| ID(XooNIps) |
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|
23008787 |
| 閲覧数(XooNIps) |
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| ダウンロード数(XooNIps) |
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|
799 |
5682.pdf (141.2 kB)
