| Item type |
学術雑誌論文 / Journal Article_02(1) |
| 公開日 |
2013-11-05 |
| タイトル |
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タイトル |
Dual-time-point F-18 FDG PET/CT imaging for differentiating the lymph nodes between malignant lymphoma and benign lesions |
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言語 |
en |
| 言語 |
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言語 |
eng |
| キーワード |
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主題Scheme |
Other |
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キーワード |
18F-FDG PET/CT |
| キーワード |
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主題Scheme |
Other |
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キーワード |
dual-time-point imaging |
| キーワード |
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主題Scheme |
Other |
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キーワード |
lymphoma |
| キーワード |
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主題Scheme |
Other |
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キーワード |
benign lymph node |
| キーワード |
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主題Scheme |
Other |
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キーワード |
standardized uptake value |
| 資源タイプ |
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資源タイプ |
journal article |
| 著者 |
中山, 理寛
Okizaki, Atsutaka
Ishitoya, Shunta
Sakaguchi, Miki
Sato, Junichi
Aburano, Tamio
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| 書誌情報 |
Annals of Nuclear Medicine
巻 27,
号 2,
p. 163-169,
発行日 2013-02-01
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| ISSN |
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収録物識別子タイプ |
PISSN |
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収録物識別子 |
0914-7187 |
| DOI |
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関連タイプ |
isVersionOf |
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識別子タイプ |
DOI |
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関連識別子 |
10.1007/s12149-012-0669-1 |
| 医中誌ID |
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関連タイプ |
isVersionOf |
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識別子タイプ |
ICHUSHI |
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関連識別子 |
2014010325 |
| 識別番号 その他 |
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内容記述タイプ |
Other |
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内容記述 |
PMID：23188388 |
| 抄録 |
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内容記述タイプ |
Abstract |
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内容記述 |
PURPOSE: The purpose of the present study is to evaluate the clinical value of dual-time-point F-18 FDG PET/CT imaging to differentiate malignant lymphoma (ML) from benign lymph node (BLN). MATERIALS AND METHODS: The subjects were 310 lymph nodes in 84 patients (195 ML lesions in 30 patients and 115 BLN in 54 patients associated with various etiologies.). F-18 FDG PET/CT scan was performed at 50 minutes (early scan) and at 100 minutes (delayed scan) after the injection. First, the maximum standardized uptake value (SUVmax) of each lesion at early and delayed scan was calculated. Second, we estimated the difference between early and delayed SUVmax (D-SUVmax) and the retention index (RI-SUVmax) to evaluate the change of tracers in the lesions. Furthermore, proper cut-off values of them were evaluated using by receiver operating characteristic analysis. The efficacy of each parameter was analyzed with ANOVA. RESULTS: Delayed SUVmax and D-SUVmax in ML were significantly higher than those in BLN. Proper cut-off value in delayed SUVmax was 4.0 and in D-SUVmax was 1.0. When the proper cut-off value in D-SUVmax was applied, the D-SUVmax yielded the role of diagnosis with sensitivity of 82.6%, specificity of 65.2%, positive predictive value of 80.1% and negative predictive value of 68.8%, respectively. CONCLUSIONS: The delayed SUVmax and D-SUVmax were useful indices to differentiate ML from BLN, regardless of histologic subtype. Dual-time-point F-18 FDG PET/CT imaging may help to consider whether there is any need to proceed to more invasive tests, such as biopsy, in individual patients. |
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言語 |
en |
| 注記 |
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内容記述タイプ |
Other |
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注記 |
Author |
| 資源タイプ |
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内容記述タイプ |
Other |
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資源タイプ |
text |
| 著者版フラグ |
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出版タイプ |
AM |
| フォーマット |
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内容記述タイプ |
Other |
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内容記述 |
application/pdf |
| ID(XooNIps) |
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23188388 |
| 閲覧数(XooNIps) |
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| ダウンロード数(XooNIps) |
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1063 |
5486.pdf (427.7 kB)
