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Dual-time-point F-18 FDG PET/CT imaging for differentiating the lymph nodes between malignant lymphoma and benign lesions

https://asahikawa-med.repo.nii.ac.jp/records/4675
https://asahikawa-med.repo.nii.ac.jp/records/4675
21951f47-46f0-47bc-93c7-53f8d5b1d361
名前 / ファイル ライセンス アクション
5486.pdf 5486.pdf (427.7 kB)
Item type 学術雑誌論文 / Journal Article_02(1)
公開日 2013-11-05
タイトル
タイトル Dual-time-point F-18 FDG PET/CT imaging for differentiating the lymph nodes between malignant lymphoma and benign lesions
言語 en
言語
言語 eng
キーワード
主題Scheme Other
キーワード 18F-FDG PET/CT
キーワード
主題Scheme Other
キーワード dual-time-point imaging
キーワード
主題Scheme Other
キーワード lymphoma
キーワード
主題Scheme Other
キーワード benign lymph node
キーワード
主題Scheme Other
キーワード standardized uptake value
資源タイプ
資源タイプ journal article
著者 中山, 理寛

× 中山, 理寛

ja 中山, 理寛

ja-Kana ナカヤマ, ミチヒロ

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Okizaki, Atsutaka

× Okizaki, Atsutaka

en Okizaki, Atsutaka

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Ishitoya, Shunta

× Ishitoya, Shunta

en Ishitoya, Shunta

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Sakaguchi, Miki

× Sakaguchi, Miki

en Sakaguchi, Miki

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Sato, Junichi

× Sato, Junichi

en Sato, Junichi

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Aburano, Tamio

× Aburano, Tamio

en Aburano, Tamio

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書誌情報 Annals of Nuclear Medicine

巻 27, 号 2, p. 163-169, 発行日 2013-02-01
ISSN
収録物識別子タイプ PISSN
収録物識別子 0914-7187
DOI
関連タイプ isVersionOf
識別子タイプ DOI
関連識別子 10.1007/s12149-012-0669-1
医中誌ID
関連タイプ isVersionOf
識別子タイプ ICHUSHI
関連識別子 2014010325
識別番号 その他
内容記述タイプ Other
内容記述 PMID:23188388
抄録
内容記述タイプ Abstract
内容記述 PURPOSE: The purpose of the present study is to evaluate the clinical value of dual-time-point F-18 FDG PET/CT imaging to differentiate malignant lymphoma (ML) from benign lymph node (BLN). MATERIALS AND METHODS: The subjects were 310 lymph nodes in 84 patients (195 ML lesions in 30 patients and 115 BLN in 54 patients associated with various etiologies.). F-18 FDG PET/CT scan was performed at 50 minutes (early scan) and at 100 minutes (delayed scan) after the injection. First, the maximum standardized uptake value (SUVmax) of each lesion at early and delayed scan was calculated. Second, we estimated the difference between early and delayed SUVmax (D-SUVmax) and the retention index (RI-SUVmax) to evaluate the change of tracers in the lesions. Furthermore, proper cut-off values of them were evaluated using by receiver operating characteristic analysis. The efficacy of each parameter was analyzed with ANOVA. RESULTS: Delayed SUVmax and D-SUVmax in ML were significantly higher than those in BLN. Proper cut-off value in delayed SUVmax was 4.0 and in D-SUVmax was 1.0. When the proper cut-off value in D-SUVmax was applied, the D-SUVmax yielded the role of diagnosis with sensitivity of 82.6%, specificity of 65.2%, positive predictive value of 80.1% and negative predictive value of 68.8%, respectively. CONCLUSIONS: The delayed SUVmax and D-SUVmax were useful indices to differentiate ML from BLN, regardless of histologic subtype. Dual-time-point F-18 FDG PET/CT imaging may help to consider whether there is any need to proceed to more invasive tests, such as biopsy, in individual patients.
言語 en
注記
内容記述タイプ Other
注記 Author
資源タイプ
内容記述タイプ Other
資源タイプ text
著者版フラグ
出版タイプ AM
フォーマット
内容記述タイプ Other
内容記述 application/pdf
ID(XooNIps)
23188388
閲覧数(XooNIps)
ダウンロード数(XooNIps)
1063
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中山, 理寛, Okizaki, Atsutaka, Ishitoya, Shunta, Sakaguchi, Miki, Sato, Junichi, Aburano, Tamio, n.d., Dual-time-point F-18 FDG PET/CT imaging for differentiating the lymph nodes between malignant lymphoma and benign lesions: 163–169 p.

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