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Role of lipid droplet proteins in liver steatosis
https://asahikawa-med.repo.nii.ac.jp/records/4313
https://asahikawa-med.repo.nii.ac.jp/records/43139f95156f-1a23-4fa2-bbda-02a34a91d103
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
5068.pdf (274.6 kB)
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| Item type | 学術雑誌論文 / Journal Article_02(1) | |||||||||
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| 公開日 | 2013-02-27 | |||||||||
| タイトル | ||||||||||
| タイトル | Role of lipid droplet proteins in liver steatosis | |||||||||
| 言語 | en | |||||||||
| 言語 | ||||||||||
| 言語 | eng | |||||||||
| キーワード | ||||||||||
| 主題Scheme | Other | |||||||||
| キーワード | Lipid droplet protein | |||||||||
| キーワード | ||||||||||
| 主題Scheme | Other | |||||||||
| キーワード | Fatty liver | |||||||||
| キーワード | ||||||||||
| 主題Scheme | Other | |||||||||
| キーワード | Perilipin family | |||||||||
| キーワード | ||||||||||
| 主題Scheme | Other | |||||||||
| キーワード | PPAR | |||||||||
| キーワード | ||||||||||
| 主題Scheme | Other | |||||||||
| キーワード | FSP27 | |||||||||
| 資源タイプ | ||||||||||
| 資源タイプ | journal article | |||||||||
| 著者 |
奥村, 利勝
× 奥村, 利勝
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| 書誌情報 |
Journal of physiology and biochemistry 巻 67, 号 4, p. 629-636, 発行日 2011-12-01 |
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| ISSN | ||||||||||
| 収録物識別子タイプ | PISSN | |||||||||
| 収録物識別子 | 1138-7548 | |||||||||
| DOI | ||||||||||
| 関連タイプ | isVersionOf | |||||||||
| 識別子タイプ | DOI | |||||||||
| 関連識別子 | 10.1007/s13105-011-0110-6 | |||||||||
| PubMed番号 | ||||||||||
| 識別子タイプ | PMID | |||||||||
| 関連識別子 | 21847662 | |||||||||
| 抄録 | ||||||||||
| 内容記述タイプ | Abstract | |||||||||
| 内容記述 | Five proteins of the perilipin (Plin) family such as Plin1 (perilipin) Plin2 (adipose differentiation-related protein), Plin3 (tail-interacting protein of 47 kDa), Plin4 (S3-12), and Plin5 (myocardial lipid droplet protein) are characterized as lipid droplet (LD) proteins in adipocytes. Recent reports have demonstrated that fat-specific protein 27 (FSP27) and hypoxia-inducible protein 2 (HIG2) are also thought to be novel LD proteins in addition to proteins of the Plin family. Growing evidence have shown that LD proteins play a role in the pathophysiology in the fatty liver disease which is characterized by hepatocytes containing LD with excessive neutral lipid. Studies showed LD proteins such as Plin1, Plin2, Plin3, Plin5, FSP27, and HIG2 are expressed in the liver steatosis. Among them, a high fat diet increases expression of Plin2 and/or FSP27 through activation of peroxisome proliferator-activated receptor γ to develop fatty liver. In this article, recent advances on the role of LD proteins in pathophysiology of fatty liver diseases are summarized. | |||||||||
| 言語 | en | |||||||||
| 注記 | ||||||||||
| 内容記述タイプ | Other | |||||||||
| 注記 | Author | |||||||||
| 資源タイプ | ||||||||||
| 内容記述タイプ | Other | |||||||||
| 資源タイプ | text | |||||||||
| 著者版フラグ | ||||||||||
| 出版タイプ | AM | |||||||||
| フォーマット | ||||||||||
| 内容記述タイプ | Other | |||||||||
| 内容記述 | application/pdf | |||||||||
| ID(XooNIps) | ||||||||||
| 21847662 | ||||||||||
| 閲覧数(XooNIps) | ||||||||||
| ダウンロード数(XooNIps) | ||||||||||
| 749 | ||||||||||
