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Involvement of corneodesmosome degradation and lamellar granule transportation in the desquamation process
https://asahikawa-med.repo.nii.ac.jp/records/4036
https://asahikawa-med.repo.nii.ac.jp/records/4036052e3fd0-7087-4119-ae1f-b6d9d30ef4d9
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
4489.pdf (910.8 kB)
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| Item type | 学術雑誌論文 / Journal Article_02(1) | |||||||||||
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| 公開日 | 2012-05-17 | |||||||||||
| タイトル | ||||||||||||
| タイトル | Involvement of corneodesmosome degradation and lamellar granule transportation in the desquamation process | |||||||||||
| 言語 | en | |||||||||||
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| 言語 | eng | |||||||||||
| 資源タイプ | ||||||||||||
| 資源タイプ | journal article | |||||||||||
| 著者 |
山本, 明美
× 山本, 明美
× Kishibe, Mari
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| 書誌情報 |
Medical Molecular Morphology 巻 44, 号 1, p. 1-6, 発行日 2011-03-01 |
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| 収録物識別子タイプ | PISSN | |||||||||||
| 収録物識別子 | 1860-1480 | |||||||||||
| DOI | ||||||||||||
| 関連タイプ | isVersionOf | |||||||||||
| 識別子タイプ | DOI | |||||||||||
| 関連識別子 | 10.1007/s00795-010-0513-4 | |||||||||||
| 抄録 | ||||||||||||
| 内容記述タイプ | Abstract | |||||||||||
| 内容記述 | Desquamation in mammalian skin is a well balanced process of producing corneocytes and shedding them from the surface of the skin. The corneodesmosome, which is a modified desmosome, is the main adhesive structure in the cornified cell layer. The major extracellular constituents of corneodesmosomes are desmoglein 1, desmocollin 1 and corneodesmosin. Proteases involved in the degradation of corneodesmosomes and their inhibitors are secreted from lamellar granules in the granular cell layer. Genetic defects in corneodesmosin and protease inhibitors result in accelerated desquamation and severe barrier impairment. Abnormalities in transportation and secretion of lamellar granules underlie ichthyosis seen in certain human diseases. | |||||||||||
| 言語 | en | |||||||||||
| 注記 | ||||||||||||
| 内容記述タイプ | Other | |||||||||||
| 注記 | http://dx.doi.org/10.1007/s00795-010-0513-4 The final publication is available at www.springerlink.com | |||||||||||
| 資源タイプ | ||||||||||||
| 内容記述タイプ | Other | |||||||||||
| 資源タイプ | text | |||||||||||
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| 出版タイプ | AM | |||||||||||
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| 内容記述タイプ | Other | |||||||||||
| 内容記述 | application/pdf | |||||||||||
| ID(XooNIps) | ||||||||||||
| 21424930 | ||||||||||||
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| ダウンロード数(XooNIps) | ||||||||||||
| 1052 | ||||||||||||
