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Pancreatic Ductal Adenocarcinomas in Long-Term Follow-Up Patients With Branch Duct Intraductal Papillary Mucinous Neoplasms

https://asahikawa-med.repo.nii.ac.jp/records/3981
https://asahikawa-med.repo.nii.ac.jp/records/3981
7c140691-3bd2-4386-a801-2a2409c243b4
名前 / ファイル ライセンス アクション
4551.pdf 4551.pdf (275.6 kB)
Item type 学術雑誌論文 / Journal Article_02(1)
公開日 2012-05-17
タイトル
タイトル Pancreatic Ductal Adenocarcinomas in Long-Term Follow-Up Patients With Branch Duct Intraductal Papillary Mucinous Neoplasms
言語 en
言語
言語 eng
資源タイプ
資源タイプ journal article
著者 丹野, 誠志

× 丹野, 誠志

ja 丹野, 誠志

ja-Kana タンノ, サトシ

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Nakano, Yasuhiro

× Nakano, Yasuhiro

en Nakano, Yasuhiro

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Koizumi, Kazuya

× Koizumi, Kazuya

en Koizumi, Kazuya

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Sugiyama, Yoshiaki

× Sugiyama, Yoshiaki

en Sugiyama, Yoshiaki

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Nakamura, Kazumasa

× Nakamura, Kazumasa

en Nakamura, Kazumasa

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Sasajima, Junpei

× Sasajima, Junpei

en Sasajima, Junpei

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Nishikawa, Tomoya

× Nishikawa, Tomoya

en Nishikawa, Tomoya

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Mizukami, Yusuke

× Mizukami, Yusuke

en Mizukami, Yusuke

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Yanagawa, Nobuyuki

× Yanagawa, Nobuyuki

en Yanagawa, Nobuyuki

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Fujii, Tsuneshi

× Fujii, Tsuneshi

en Fujii, Tsuneshi

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Okumura, Toshikatsu

× Okumura, Toshikatsu

en Okumura, Toshikatsu

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Obara, Takeshi

× Obara, Takeshi

en Obara, Takeshi

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Kohgo, Yutaka

× Kohgo, Yutaka

en Kohgo, Yutaka

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書誌情報 Pancreas

巻 39, 号 1, p. 36-40, 発行日 2010-01-01
ISSN
収録物識別子タイプ PISSN
収録物識別子 0885-3177
DOI
識別子タイプ DOI
関連識別子 10.1097/MPA.0b013e3181b91cd0
リンクURL
内容記述タイプ Other
内容記述 This is a non-final version of an article published in final form in Tanno, Satoshi ; Nakano, Yasuhiro ; Koizumi, Kazuya ; Sugiyama, Yoshiaki ; Nakamura, Kazumasa ; Sasajima, Junpei ; Nishikawa, Tomoya ; Mizukami, Yusuke ; Yanagawa, Nobuyuki ; Fujii, Tsuneshi ; Okumura, Toshikatsu ; Obara, Takeshi ; Kohgo, Yutaka, Pancreas, 39(1), 36-40. | This is a non-final version of an article published in final form in Tanno, Satoshi ; Nakano, Yasuhiro ; Koizumi, Kazuya ; Sugiyama, Yoshiaki ; Nakamura, Kazumasa ; Sasajima, Junpei ; Nishikawa, Tomoya ; Mizukami, Yusuke ; Yanagawa, Nobuyuki ; Fujii, Tsuneshi ; Okumura, Toshikatsu ; Obara, Takeshi ; Kohgo, Yutaka, Pancreas, 39(1), 36-40.
抄録
内容記述タイプ Abstract
内容記述 Objective: Although branch duct intraductal papillary mucinous neoplasms (BD-IPMNs) are slow-growing tumors with a favorable prognosis, the synchronous occurrence of pancreatic ductal adenocarcinomas (PDAs) in patients with BD-IPMNs has been reported. This study was aimed to elucidate the development of PDAs in long-term follow-up patients with BD-IPMNs. Methods: We investigated 89 BD-IPMN patients who had no mural nodules and followed them up conservatively at least 2 years (median follow-up, 64 months; range, 25-158 months). All subjects underwent examinations by imaging modalities including endoscopic retrograde pancreatography. We calculated the standardized incidence ratio (SIR) from the vital statistics compiled by the Ministry of Health, Labor, and Welfare of Japan. Results: Among the 89 patients, 4 cases of PDAs distant from BD-IPMN were observed in 552 patient-years of follow-up (7.2 per 1000 patient-years). The expected number was 0.25, and the SIR of PDAs was 15.8 (95% confidence interval [CI], 4.3-40.4; P = 0.00014). Subgroup analyses showed that the incidence of PDAs was significantly increased in patients 70 years or older (SIR 16.7; 95% CI, 3.4-48.7; P = 0.0008) and in women (SIR 22.5; 95% CI, 2.7-81.1; P = 0.0037). Conclusions: Patients with BD-IPMNs are at a high risk for PDAs. During the follow-up, careful examination is required to detect the development of PDAs in patients with BD-IPMNs.
言語 en
注記
内容記述タイプ Other
注記 http://journals.lww.com/pancreasjournal/pages/default.aspx
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資源タイプ text
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出版タイプ AM
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内容記述 application/pdf
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