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Retrospective Comparison of the Efficacy of Tonsillectomy with and without Steroid-pulse Therapy in IgA Nephropathy Patients.

https://asahikawa-med.repo.nii.ac.jp/records/3916
https://asahikawa-med.repo.nii.ac.jp/records/3916
fedfdbd6-0e9a-4e88-8585-8c09d42769a0
名前 / ファイル ライセンス アクション
4633.pdf 4633.pdf (192.2 kB)
Item type 学術雑誌論文 / Journal Article_02(1)
公開日 2012-06-28
タイトル
タイトル Retrospective Comparison of the Efficacy of Tonsillectomy with and without Steroid-pulse Therapy in IgA Nephropathy Patients.
言語 en
言語
言語 eng
キーワード
主題Scheme Other
キーワード clinical remission
キーワード
主題Scheme Other
キーワード IgA nephropathy
キーワード
主題Scheme Other
キーワード methylprednisolone pulse
キーワード
主題Scheme Other
キーワード tonsillectomy
資源タイプ
資源タイプ journal article
著者 中川, 直樹

× 中川, 直樹

ja 中川, 直樹

ja-Kana ナカガワ, ナオキ

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Kabara, Maki

× Kabara, Maki

en Kabara, Maki

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Matsuki, Motoki

× Matsuki, Motoki

en Matsuki, Motoki

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Chinda, Junko

× Chinda, Junko

en Chinda, Junko

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Fujino, Takayuki

× Fujino, Takayuki

en Fujino, Takayuki

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Hirayama, Tomoya

× Hirayama, Tomoya

en Hirayama, Tomoya

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Takahara, Miki

× Takahara, Miki

en Takahara, Miki

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Harabuchi, Yasuaki

× Harabuchi, Yasuaki

en Harabuchi, Yasuaki

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Kikuchi, Kenjiro

× Kikuchi, Kenjiro

en Kikuchi, Kenjiro

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Hasebe, Naoyuki

× Hasebe, Naoyuki

en Hasebe, Naoyuki

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書誌情報 Internal Medicine

巻 51, 号 11, p. 1323-1328, 発行日 2012-01-01
ISSN
収録物識別子タイプ PISSN
収録物識別子 0918-2918
DOI
関連タイプ isVersionOf
識別子タイプ DOI
関連識別子 10.2169/internalmedicine.51.7238
抄録
内容記述タイプ Abstract
内容記述 Objective Tonsillectomy and steroid-pulse (TSP) therapy have been proposed as a curative treatment for immunoglobulin A nephropathy (IgAN) in Japan. However, we sometimes encounter patients who reject steroid-pulse therapy because of concerns about the side effects of corticosteroids. Here, we examined the efficacy of TSP therapy and tonsillectomy alone for IgAN with urinary abnormalities. Methods Data on 40 IgAN patients diagnosed by renal biopsies, who presented glomerular hematuria and proteinuria at baseline and underwent bilateral palatine tonsillectomy, were analyzed retrospectively. Twenty of them underwent TSP therapy (TSP group), and 20 underwent tonsillectomy alone (T group). We examined associations between therapies, changes in urinary findings and renal function, and subsequent clinical remission (CR), defined as negative proteinuria and urinary erythrocytes of less than 5/high-power field. Results TSP group showed a significant decrease in proteinuria and hematuria earlier than T group. The rates of CR were significantly higher in TSP group compared with T group on the final observation period (75% vs. 45%, p<0.05). There was a significant difference between CR group and non-CR group only in the rate of receiving TSP therapy. Conclusion TSP therapy significantly increased the probability of CR compared with tonsillectomy alone in IgAN patients with urinary abnormalities.
言語 en
注記
内容記述タイプ Other
注記 著者最終原稿版
資源タイプ
内容記述タイプ Other
資源タイプ text
著者版フラグ
出版タイプ AM
フォーマット
内容記述タイプ Other
内容記述 application/pdf
ID(XooNIps)
Inter-Med-51-11-1323
閲覧数(XooNIps)
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