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Decrease in heart rates by artificial CO2 hot spring bathing is inhibited by beta(1)-adrenoceptor blockade in anesthetized rats

https://asahikawa-med.repo.nii.ac.jp/records/3325
https://asahikawa-med.repo.nii.ac.jp/records/3325
d50a475a-9bbe-4865-9530-29fcdf30fcb2
名前 / ファイル ライセンス アクション
213.pdf 213.pdf (276.1 kB)
Item type 学術雑誌論文 / Journal Article_02(1)
公開日 2007-02-14
タイトル
タイトル Decrease in heart rates by artificial CO2 hot spring bathing is inhibited by beta(1)-adrenoceptor blockade in anesthetized rats
言語 en
言語
言語 eng
資源タイプ
資源タイプ journal article
著者 橋本, 眞明

× 橋本, 眞明

ja 橋本, 眞明

ja-Kana ハシモト, マサアキ

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Yamamoto, N

× Yamamoto, N

en Yamamoto, N

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著者 ローマ字
Hashimoto, Masaaki
著者 ローマ字
en
書誌情報 JOURNAL OF APPLIED PHYSIOLOGY

巻 96, 号 1, p. 226-232, 発行日 2004-01-01
ISSN
収録物識別子タイプ ISSN
収録物識別子 8750-7587
DOI
識別子タイプ DOI
関連識別子 10.1152/japplphysiol.00812.2003
リンクURL
内容記述タイプ Other
内容記述 http://jap.physiology.org/cgi/content/abstract/96/1/226?maxtoshow=&HITS=10&hits=10&RESULTFORMAT=&andorexactfulltext=and&searchid=1&FIRSTINDEX=0&sortspec=relevance&volume=96&firstpage=226&resourcetype=HWCIT | http://jap.physiology.org/cgi/content/abstract/96/1/226?maxtoshow=&HITS=10&hits=10&RESULTFORMAT=&andorexactfulltext=and&searchid=1&FIRSTINDEX=0&sortspec=relevance&volume=96&firstpage=226&resourcetype=HWCIT
抄録
内容記述タイプ Abstract
内容記述 To investigate the effects of carbon dioxide (CO_2) hot spring baths on physiological functions, head-out immersion of urethane-anesthetized, fursheared male Wistar rats was performed. Animals were immersed in water (30 or 35°C) with high-CO_2 content (?1,000 parts/million; CO_2-water). CO_2-water for bathing was made by using an artificial spa maker with normal tap water and high-pressure CO_2 from a gas cylinder. When a human foot was immersed for 10 min in the CO_2-water at 35°C, the immersed skin reddened, whereas skin color did not change in normal tap water at the same temperature. Arterial blood pressure, heart rate (HR), underwater skin tissue blood flow, and temperatures of the colon and immersed skin were continuously measured while animals were immersed in a bathtub of water for ?30 min at room temperature (26°C). Immersed skin vascular resistance, computed from blood pressure and tissue blood flow, was significantly lower in the CO_2-water bath than in tap water at 30°C, but no differences were apparent at 35°C. HR of rats in CO_2-water was significantly slower than in tap water at 35°C. Decreased HR in CO_2-water was inhibited by infusion of atenolol (β1-adrenoceptor blocker), but it was unaffected by atropine (muscarinic cholinoceptor blocker). Theses results suggest that bradycardia in CO_2 hot spring bathing is caused by inhibition of the cardiac sympathetic innervation. This CO_2-water maker should prove a useful device for acquiring physiological evidence of balneotherapy.
言語 en
注記
内容記述タイプ Other
注記 Hashimoto, M; Yamamoto, N, JOURNAL OF APPLIED PHYSIOLOGY, 96(1), 226-232, 2004. "Copyright 2004 by the American Physical Society." publisher
言語 en
資源タイプ
内容記述タイプ Other
資源タイプ text
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内容記述 application/pdf
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橋本, 眞明, Yamamoto, N, n.d., Decrease in heart rates by artificial CO2 hot spring bathing is inhibited by beta(1)-adrenoceptor blockade in anesthetized rats: 226–232 p.

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