| Item type |
学術雑誌論文 / Journal Article_02(1) |
| 公開日 |
2010-01-20 |
| タイトル |
|
|
タイトル |
Cerebral control of bladder storage in patients with detrusor overactivity |
|
言語 |
en |
| 言語 |
|
|
言語 |
eng |
| キーワード |
|
|
主題Scheme |
Other |
|
キーワード |
bladder storage |
| キーワード |
|
|
主題Scheme |
Other |
|
キーワード |
detrusor overactivity |
| キーワード |
|
|
主題Scheme |
Other |
|
キーワード |
NEUROSTAT |
| キーワード |
|
|
主題Scheme |
Other |
|
キーワード |
Tc-99m HMPAO |
| キーワード |
|
|
主題Scheme |
Other |
|
キーワード |
SPECT |
| 資源タイプ |
|
|
資源タイプ |
journal article |
| 著者 |
Yafu, Yin
Noriyuki, Shuke
Shigeo, Kaneko
Atsutaka, Okizaki
Junichi, Sato
Tamio, Aburano
Yaming, Li
Mitsuhiro, Mizunaga
Sunao, Yachiku
|
| 書誌情報 |
Nuclear Medicine Communications
巻 29,
号 12,
p. 1081-1085,
発行日 2008-12-01
|
| ISSN |
|
|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
0143-3636 |
| 抄録 |
|
|
内容記述タイプ |
Abstract |
|
内容記述 |
Objective: To identify the brain areas which control the bladder storage by Tc-99m HMPAO SPECT with Neurological Statistical Image Analysis Software (NEUROSTAT) in patients with detrusor overactivity (DO).
Methods: SPECT scans were performed on nineteen patients with DO. And eight patients with normal detrusor function, who has some storage symptoms of lower urinary tract as the patients with DO, also had SPECT scan, as control. All the subjects were male and right-handed, and were scanned twice under two conditions: resting state and urine withholding state. NEUROSTAT was adopted to analyze the difference in brain blood perfusion between groups and states. The results were displayed on Z-score images at a significance threshold of P < 0.05 with correction for multiple comparisons.
Results: No region reached significant threshold in comparison of patients with DO and normal detrusor function in resting state. There were significant increases in tracer activity in the right inferior frontal gyrus and the right middle temporal gyrus during urine withholding state as compared with resting state in patients with normal detrusor function. Among the regions, the right inferior frontal gyrus was distinctly prominent at both Z-score and the extent. The regions that were activated significantly in patients with normal detrusor function, did not reach significant threshold during urine withholding in patients with DO.
Conclusions: The study indicated that the right inferior frontal gyrus and the right middle temporal gyrus, especially the right inferior frontal gyrus, played a role in cerebral control of bladder storage, inhibiting the contraction of detrusor in urine storage. |
| 注記 |
|
|
内容記述タイプ |
Other |
|
注記 |
author |
|
言語 |
en |
| 資源タイプ |
|
|
内容記述タイプ |
Other |
|
資源タイプ |
text |
| 著者版フラグ |
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|
出版タイプ |
AM |
| フォーマット |
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|
内容記述タイプ |
Other |
|
内容記述 |
application/pdf |
| ID(XooNIps) |
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|
|
Yafu-3473 |
| 閲覧数(XooNIps) |
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| ダウンロード数(XooNIps) |
|
|
|
1633 |
2629.pdf (378.3 kB)
