| Item type |
学術雑誌論文 / Journal Article_02(1) |
| 公開日 |
2025-06-17 |
| タイトル |
|
|
タイトル |
Carbazochrome sodium sulfonate is not effective for prevention of post-gastric endoscopic submucosal dissection bleeding: A retrospective study |
|
言語 |
en |
| 言語 |
|
|
言語 |
eng |
| キーワード |
|
|
主題Scheme |
Other |
|
キーワード |
Carbazochrome |
| キーワード |
|
|
主題Scheme |
Other |
|
キーワード |
ESD |
| キーワード |
|
|
主題Scheme |
Other |
|
キーワード |
Gastric neoplasm |
| キーワード |
|
|
主題Scheme |
Other |
|
キーワード |
Post-operative hemorrhage |
| キーワード |
|
|
主題Scheme |
Other |
|
キーワード |
Prevention |
| 資源タイプ |
|
|
資源タイプ |
journal article |
| アクセス権 |
|
|
アクセス権 |
open access |
|
アクセス権URI |
http://purl.org/coar/access_right/c_abf2 |
| 著者 |
Keitaro, Takahashi
Takahiro, Sasaki
Nobuhiro, Ueno
Kyoko, Uehara
Yu, Kobayashi
Yuya, Sugiyama
Yuki, Murakami
Takehito, Kunogi
Katsuyoshi, Ando
Shin, Kashima
Kentaro, Moriichi
Hiroki, Tanabe
Toshikatsu, Okumura
Mikihiro, Fujiya
|
| bibliographic_information |
en : Surgical Endoscopy
巻 36,
号 10,
p. 7486-7493,
発行日 2022-10-01
|
| ISSN |
|
|
収録物識別子タイプ |
PISSN |
|
収録物識別子 |
0930-2794 |
| ISSN |
|
|
収録物識別子タイプ |
EISSN |
|
収録物識別子 |
1432-2218 |
| DOI |
|
|
関連タイプ |
isIdenticalTo |
|
|
識別子タイプ |
DOI |
|
|
関連識別子 |
https://doi.org/10.1007/s00464-022-09171-4 |
| リンクURL |
|
|
内容記述タイプ |
Other |
|
内容記述 |
https://link.springer.com/article/10.1007/s00464-022-09171-4 |
|
言語 |
en |
| item_1716186501932 |
|
|
関連タイプ |
isIdenticalTo |
|
|
識別子タイプ |
PMID |
|
|
関連識別子 |
35257213 |
| item_5_description_33 |
|
|
内容記述タイプ |
Abstract |
|
内容記述 |
Background: Carbazochrome sodium sulfonate (CSS) is conventionally administered to prevent post-endoscopic submucosal dissection (ESD) bleeding in many institutions, but research on its preventive efficacy is lacking. Therefore, we investigated the risk of post-ESD bleeding and the preventive efficacy of CSS administration.
Methods: We retrospectively reviewed 304 lesions in 259 patients with gastric neoplasms who underwent ESD at Asahikawa Medical University Hospital from 2014 to 2021. In the CSS group, CSS 100 mg/day was intravenously infused with maintenance fluid replacement on postoperative days 0-2. The risk factors of post-ESD bleeding, including CSS administration, were investigated.
Results: The overall rate of post-ESD bleeding was 4.6% (14/304). The univariate analysis showed that atrial fibrillation (Af), warfarin intake, heparin replacement, and tumor location in the lower third were significant risk factors for increasing the likelihood of postoperative bleeding. In the multivariate analysis, Af (odds ratio [OR] 3.83, 95% CI 1.02-14.30; p < 0.05), heparin replacement (OR 4.60, 95% CI 1.02-20.70; p < 0.05), and tumor location in the lower third of the stomach (OR 6.67, 95% CI 1.43-31.00; p < 0.05) were independent factors for post-ESD bleeding. Post-ESD bleeding was observed in 5.2% (9/174) of the CSS group and 3.8% (5/130) of the non-CSS group, with no significant difference between the two groups (p = 0.783). Additionally, CSS was not shown to have preventive effects in groups with higher-risk factors, such as Af diagnosis, warfarin use, heparin replacement, and tumor location in the lower third of the stomach.
Conclusion: CSS administration was not effective for the prevention of the post-ESD bleeding in the overall patient population as well as in higher-risk patients. This suggests that the administration of CSS for post-ESD bleeding prevention may need to be reconsidered. |
|
言語 |
en |
| 注記 |
|
|
内容記述タイプ |
Other |
|
注記 |
This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. |
|
言語 |
en |
| 出版タイプ |
|
|
出版タイプ |
VoR |
| item_5_textarea_42 |
|
|
|
en |
|
|
© 2022. The Author(s). |
35257213.pdf (798 KB)
.png)
