| Item type |
学術雑誌論文 / Journal Article_02(1) |
| 公開日 |
2025-05-26 |
| タイトル |
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タイトル |
Glaucoma Diagnostic Performance of Retinal Blood Flow Measurement With Doppler Optical Coherence Tomography |
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言語 |
en |
| 言語 |
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言語 |
eng |
| 資源タイプ |
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資源タイプ |
journal article |
| アクセス権 |
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アクセス権 |
open access |
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アクセス権URI |
http://purl.org/coar/access_right/c_abf2 |
| 著者 |
Tsubasa, Abe
Takafumi, Yoshioka
Youngseok, Song
Tomofumi, Tani
Motofumi, Kawai
Tsuneaki, Omae
Kengo, Takahashi
Yoshitaka, Takizawa
Tomoko, Ro-Mase
Satoshi, Ishiko
Kana, Minamide
Jun, Sakai
Masahiro, Akiba
Yohei, Hashimoto
Akitoshi, Yoshida
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| bibliographic_information |
en : Translational vision science and technology
巻 11,
号 10,
p. 11,
発行日 2022-10-03
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| ISSN |
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収録物識別子タイプ |
EISSN |
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収録物識別子 |
2164-2591 |
| DOI |
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関連タイプ |
isIdenticalTo |
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識別子タイプ |
DOI |
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関連識別子 |
https://doi.org/10.1167/tvst.11.10.11 |
| item_1716186501932 |
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関連タイプ |
isIdenticalTo |
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識別子タイプ |
PMID |
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関連識別子 |
36201201 |
| item_5_description_33 |
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内容記述タイプ |
Abstract |
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内容記述 |
Purpose: The purpose of this study was to evaluate the diagnostic performance of retinal blood flow (RBF) measured with the Doppler optical coherence tomography (OCT) segmental scanning method to distinguish between healthy and glaucoma eyes.
Methods: Fifty-eight patients with normal tension glaucoma (NTG) who had a single-hemifield visual field defect and 44 age-matched healthy subjects were enrolled. Retinal nerve fiber layer thickness (RNFLT) was measured with swept-source OCT. Superior and inferior temporal arteries (TAs) and temporal veins (TVs) RBF were measured with Doppler OCT. The area under the curve (AUC) of the receiver operating characteristic (ROC) was used to compare the diagnostic performances in the damaged and normal hemispheres.
Results: Multivariate regression analysis showed TA RBF and TV RBF were significantly reduced in the damaged and normal hemispheres. The ROC analysis showed that the AUC for quadrant RNFLT, TA RBF, and TV RBF were 0.973, 0.909, and 0.872 in the damaged hemisphere, respectively. The AUC values in the normal hemisphere were 0.783, 0.744, and 0.697, respectively. The combination of quadrant RNFLT and TA/TV RBF had a greater AUC than quadrant RNFLT alone in both damaged (AUC = 0.987) and normal (AUC = 0.825) hemispheres.
Conclusions: In NTG eyes with single-hemifield damage, the RBF was found to be significantly reduced in the damaged and normal hemispheres independent from structural changes. The combination of RNFLT and RBF could improve diagnostic performances for glaucoma.
Translational relevance: Combining morphological and blood flow measurements with Doppler OCT may be useful in glaucoma diagnosis. |
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言語 |
en |
| 注記 |
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内容記述タイプ |
Other |
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注記 |
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. |
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言語 |
en |
| 出版タイプ |
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出版タイプ |
VoR |
| item_5_textarea_42 |
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en |
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Copyright 2022 The Authors |
36201201.pdf (2.8 MB)
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