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Severity of low pre-pregnancy body mass index and perinatal outcomes:the Japan Environment and Children's Study

https://asahikawa-med.repo.nii.ac.jp/records/2000321
https://asahikawa-med.repo.nii.ac.jp/records/2000321
ffd3181f-4b78-42f3-b093-633a6caa35f9
名前 / ファイル ライセンス アクション
K593 K593 Nakanishi Kentaro_TD.pdf (1.1 MB)
Item type 学位論文 / Thesis or Dissertation_02(1)
公開日 2025-02-10
タイトル
タイトル Severity of low pre-pregnancy body mass index and perinatal outcomes:the Japan Environment and Children's Study
言語 en
言語
言語 eng
キーワード
言語 en
主題Scheme Other
主題 Adverse perinatal outcomes
キーワード
言語 en
主題Scheme Other
主題 Low birth weight
キーワード
言語 en
主題Scheme Other
主題 Maternal body mass index
キーワード
言語 en
主題Scheme Other
主題 Preterm birth
キーワード
言語 en
主題Scheme Other
主題 Small-for-gestational age
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_db06
資源タイプ doctoral thesis
アクセス権
アクセス権 open access
アクセス権URI http://purl.org/coar/access_right/c_abf2
その他(別言語等)のタイトル
その他のタイトル 母体の妊娠前の低体格指数の重症度と周産期転帰との関連:エコチル調査
言語 ja
著者 中西, 研太郎

× 中西, 研太郎

ja 中西, 研太郎

ja-Kana ナカニシ, ケンタロウ

en Nakanishi, Kentaro

Search repository
bibliographic_information en : BMC Pregnancy Childbirth

巻 22, 号 1, p. 121, 発行日 2022-02-11
ISSN
収録物識別子タイプ EISSN
収録物識別子 1471-2393
DOI
関連タイプ isIdenticalTo
識別子タイプ DOI
関連識別子 https://doi.org/10.1186/s12884-022-04418-3
識別番号 その他
内容記述タイプ Other
内容記述 PMID:35148693
言語 en
dissertation_number
学位授与番号 甲第593号
学位授与年月日
学位授与年月日 2023-09-29
学位名
言語 ja
学位名 博士(医学)
item_10_degree_grantor_32
言語 ja
学位授与機関名 旭川医科大学
item_10_description_33
内容記述タイプ Abstract
内容記述 Background: The extremes of maternal pre-pregnancy body mass index (BMI) are known to be risk factors associated with obstetric and adverse perinatal outcomes. Among Japanese women aged 20 years or older, the prevalence of underweight (BMI < 18.5 kg/m2) was 11.5% in 2019. Maternal thinness is a health problem caused by the desire to become slim. This study aimed to investigate the association between the severity of maternal low pre-pregnancy BMI and adverse perinatal outcomes, including preterm birth (PTB), low birth weight (LBW), and small-for-gestational age (SGA).

Methods: We conducted a prospective cohort study using data from the Japan Environment and Children's Study, which recruited pregnant individuals between 2011 and 2014. Pre-pregnancy BMI was categorized as severe-moderate underweight (BMI < 16.9 kg/m2), mild underweight (BMI, 17.0-18.4 kg/m2), low-normal weight (BMI, 18.5-19.9 kg/m2), high-normal weight (BMI, 20.0-22.9 kg/m2), overweight (BMI, 23.0-24.9 kg/m2), and obese (BMI ≥ 25.0 kg/m2). The high-normal weight group was used as the reference for statistical analyses. Adjusted logistic regression was performed to evaluate the association between pre-pregnancy BMI and PTB, LBW, and SGA.

Results: Of 92,260 singleton pregnant individuals, the prevalence was 2.7% for severe-moderate underweight, 12.9% for mild underweight, and 24.5% for low-normal weight. The prevalence of adverse outcomes was 4.6% for PTB, 8.1% for LBW, and 7.6% for SGA. The adjusted odds ratios (aORs) for PTB were 1.72 (95% confidence interval [CI], 1.46-2.03) for severe-moderate underweight and 1.26 (95% CI, 1.14-1.39) for mild underweight. The aORs of LBW were 2.55 (95% CI, 2.27-2.86) for severe-moderate underweight, 1.64 (95% CI, 1.53-1.76) for mild underweight, and 1.23 (95% CI, 1.16-1.31) for low-normal weight. The aORs of SGA were 2.53 (95% CI, 2.25-2.84) for severe-moderate underweight, 1.66 (95% CI, 1.55-1.79) for mild underweight, and 1.29 (95% CI, 1.21-1.38) for low-normal weight.

Conclusions: A dose-response relationship was found between the severity of low pre-pregnancy BMI and PTB, LBW, and SGA. Even low-normal BMI (18.5-19.9 kg/m2) increased the risk of LBW and SGA. This study provides useful information for pre-conception counseling in lean individuals.
言語 en
出版タイプ
出版タイプ VoR
出版タイプResource http://purl.org/coar/version/c_970fb48d4fbd8a85
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中西, 研太郎, n.d., Severity of low pre-pregnancy body mass index and perinatal outcomes:the Japan Environment and Children&#39;s Study: 121– p.

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