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Severity of low pre-pregnancy body mass index and perinatal outcomes:the Japan Environment and Children's Study
https://asahikawa-med.repo.nii.ac.jp/records/2000321
https://asahikawa-med.repo.nii.ac.jp/records/2000321ffd3181f-4b78-42f3-b093-633a6caa35f9
名前 / ファイル | ライセンス | アクション |
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Item type | 学位論文 / Thesis or Dissertation_02(1) | |||||||||||
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公開日 | 2025-02-10 | |||||||||||
タイトル | ||||||||||||
タイトル | Severity of low pre-pregnancy body mass index and perinatal outcomes:the Japan Environment and Children's Study | |||||||||||
言語 | en | |||||||||||
言語 | ||||||||||||
言語 | eng | |||||||||||
キーワード | ||||||||||||
言語 | en | |||||||||||
主題Scheme | Other | |||||||||||
主題 | Adverse perinatal outcomes | |||||||||||
キーワード | ||||||||||||
言語 | en | |||||||||||
主題Scheme | Other | |||||||||||
主題 | Low birth weight | |||||||||||
キーワード | ||||||||||||
言語 | en | |||||||||||
主題Scheme | Other | |||||||||||
主題 | Maternal body mass index | |||||||||||
キーワード | ||||||||||||
言語 | en | |||||||||||
主題Scheme | Other | |||||||||||
主題 | Preterm birth | |||||||||||
キーワード | ||||||||||||
言語 | en | |||||||||||
主題Scheme | Other | |||||||||||
主題 | Small-for-gestational age | |||||||||||
資源タイプ | ||||||||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_db06 | |||||||||||
資源タイプ | doctoral thesis | |||||||||||
アクセス権 | ||||||||||||
アクセス権 | open access | |||||||||||
アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||||||||
その他(別言語等)のタイトル | ||||||||||||
その他のタイトル | 母体の妊娠前の低体格指数の重症度と周産期転帰との関連:エコチル調査 | |||||||||||
言語 | ja | |||||||||||
著者 |
中西, 研太郎
× 中西, 研太郎
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bibliographic_information |
en : BMC Pregnancy Childbirth 巻 22, 号 1, p. 121, 発行日 2022-02-11 |
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ISSN | ||||||||||||
収録物識別子タイプ | EISSN | |||||||||||
収録物識別子 | 1471-2393 | |||||||||||
DOI | ||||||||||||
関連タイプ | isIdenticalTo | |||||||||||
識別子タイプ | DOI | |||||||||||
関連識別子 | https://doi.org/10.1186/s12884-022-04418-3 | |||||||||||
識別番号 その他 | ||||||||||||
内容記述タイプ | Other | |||||||||||
内容記述 | PMID:35148693 | |||||||||||
言語 | en | |||||||||||
dissertation_number | ||||||||||||
学位授与番号 | 甲第593号 | |||||||||||
学位授与年月日 | ||||||||||||
学位授与年月日 | 2023-09-29 | |||||||||||
学位名 | ||||||||||||
言語 | ja | |||||||||||
学位名 | 博士(医学) | |||||||||||
item_10_degree_grantor_32 | ||||||||||||
言語 | ja | |||||||||||
学位授与機関名 | 旭川医科大学 | |||||||||||
item_10_description_33 | ||||||||||||
内容記述タイプ | Abstract | |||||||||||
内容記述 | Background: The extremes of maternal pre-pregnancy body mass index (BMI) are known to be risk factors associated with obstetric and adverse perinatal outcomes. Among Japanese women aged 20 years or older, the prevalence of underweight (BMI < 18.5 kg/m2) was 11.5% in 2019. Maternal thinness is a health problem caused by the desire to become slim. This study aimed to investigate the association between the severity of maternal low pre-pregnancy BMI and adverse perinatal outcomes, including preterm birth (PTB), low birth weight (LBW), and small-for-gestational age (SGA). Methods: We conducted a prospective cohort study using data from the Japan Environment and Children's Study, which recruited pregnant individuals between 2011 and 2014. Pre-pregnancy BMI was categorized as severe-moderate underweight (BMI < 16.9 kg/m2), mild underweight (BMI, 17.0-18.4 kg/m2), low-normal weight (BMI, 18.5-19.9 kg/m2), high-normal weight (BMI, 20.0-22.9 kg/m2), overweight (BMI, 23.0-24.9 kg/m2), and obese (BMI ≥ 25.0 kg/m2). The high-normal weight group was used as the reference for statistical analyses. Adjusted logistic regression was performed to evaluate the association between pre-pregnancy BMI and PTB, LBW, and SGA. Results: Of 92,260 singleton pregnant individuals, the prevalence was 2.7% for severe-moderate underweight, 12.9% for mild underweight, and 24.5% for low-normal weight. The prevalence of adverse outcomes was 4.6% for PTB, 8.1% for LBW, and 7.6% for SGA. The adjusted odds ratios (aORs) for PTB were 1.72 (95% confidence interval [CI], 1.46-2.03) for severe-moderate underweight and 1.26 (95% CI, 1.14-1.39) for mild underweight. The aORs of LBW were 2.55 (95% CI, 2.27-2.86) for severe-moderate underweight, 1.64 (95% CI, 1.53-1.76) for mild underweight, and 1.23 (95% CI, 1.16-1.31) for low-normal weight. The aORs of SGA were 2.53 (95% CI, 2.25-2.84) for severe-moderate underweight, 1.66 (95% CI, 1.55-1.79) for mild underweight, and 1.29 (95% CI, 1.21-1.38) for low-normal weight. Conclusions: A dose-response relationship was found between the severity of low pre-pregnancy BMI and PTB, LBW, and SGA. Even low-normal BMI (18.5-19.9 kg/m2) increased the risk of LBW and SGA. This study provides useful information for pre-conception counseling in lean individuals. |
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言語 | en | |||||||||||
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出版タイプ | VoR | |||||||||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 |