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Paragonimiasis in Cameroon: molecular identification, serodiagnosis and clinical manifestations

https://asahikawa-med.repo.nii.ac.jp/records/1521
https://asahikawa-med.repo.nii.ac.jp/records/1521
71fd574f-3387-4ada-a794-2494b4d5201e
名前 / ファイル ライセンス アクション
2034.pdf 2034.pdf (954.6 kB)
Item type 学術雑誌論文 / Journal Article_02(1)
公開日 2009-04-24
タイトル
タイトル Paragonimiasis in Cameroon: molecular identification, serodiagnosis and clinical manifestations
言語 en
言語
言語 eng
資源タイプ
資源タイプ journal article
著者 伊藤, 亮

× 伊藤, 亮

ja 伊藤, 亮

ja-Kana イトウ, アキラ

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Nkouawa, A

× Nkouawa, A

en Nkouawa, A

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Okamoto, M

× Okamoto, M

Okamoto, M

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Mabou, AK

× Mabou, AK

en Mabou, AK

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Edinga, E

× Edinga, E

Edinga, E

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Yamasaki, H

× Yamasaki, H

en Yamasaki, H

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Sako, Y

× Sako, Y

en Sako, Y

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Nakao, M

× Nakao, M

en Nakao, M

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Nakaya, K

× Nakaya, K

en Nakaya, K

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Blair, D

× Blair, D

en Blair, D

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Agatusma, T

× Agatusma, T

en Agatusma, T

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Enyong, P

× Enyong, P

en Enyong, P

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Shibahara, T

× Shibahara, T

en Shibahara, T

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Moyou-Somo, R

× Moyou-Somo, R

en Moyou-Somo, R

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著者 ローマ字
Ito, Akira
著者 ローマ字
en
書誌情報 Transactions of the Royal Society of Tropical Medicine and Hygiene

巻 103, 号 3, p. 255-261, 発行日 2009-03-01
ISSN
収録物識別子タイプ ISSN
収録物識別子 0035-9203
DOI
関連タイプ isVersionOf
識別子タイプ DOI
関連識別子 10.1016/j.trstmh.2008.09.014
リンクURL
内容記述タイプ Other
内容記述 http://dx.doi.org/10.1016/j.trstmh.2008.09.014 | http://dx.doi.org/10.1016/j.trstmh.2008.09.014
抄録
内容記述タイプ Abstract
内容記述 Paragonimiasis is a common parasitic zoonosis in Cameroon and neighbouring countries in Western Africa. Serum, sputum and faecal samples were collected in an endemic area of South West Province, Cameroon, after administration of a questionnaire to identify individuals with appropriate symptoms and histories. Microscopic examination revealed eggs in sputum from 16 people, but none in any faecal sample. These 16 were among the 25 and 26 people, respectively, positive by ELISA and by immunoblot using Paragonimus africanus crude antigens. Copro-DNA detection was attempted using 23 faecal samples (18 from sputum egg-negative and five from sputum egg-positive individuals). Copro-DNA was detected in four of the five sputum egg-positive individuals. These results strongly suggest that: (1) serology is much more sensitive than sputum examination for diagnosis of paragonimiasis; and (2) a copro-DNA test may be more sensitive than a microscopic search for eggs in faeces. Molecular sequence data from ITS2 and cox1 genes confirmed that adult worms experimentally raised in cats were P. africanus and that eggs from sputum or other worm products from human faeces also belonged to this species. Based on these results, 26 of 168 persons (15.5%) were diagnosed as suffering from paragonimiasis.
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言語 en
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内容記述タイプ Other
資源タイプ text
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内容記述 application/pdf
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18992906
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