| Item type |
学術雑誌論文 / Journal Article_02(1) |
| 公開日 |
2009-04-24 |
| タイトル |
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タイトル |
Paragonimiasis in Cameroon: molecular identification, serodiagnosis and clinical manifestations |
|
言語 |
en |
| 言語 |
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|
言語 |
eng |
| 資源タイプ |
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|
資源タイプ |
journal article |
| 著者 |
伊藤, 亮
Nkouawa, A
Okamoto, M
Mabou, AK
Edinga, E
Yamasaki, H
Sako, Y
Nakao, M
Nakaya, K
Blair, D
Agatusma, T
Enyong, P
Shibahara, T
Moyou-Somo, R
|
| 著者 ローマ字 |
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|
|
Ito, Akira |
| 著者 ローマ字 |
|
|
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en |
| 書誌情報 |
Transactions of the Royal Society of Tropical Medicine and Hygiene
巻 103,
号 3,
p. 255-261,
発行日 2009-03-01
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| ISSN |
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収録物識別子タイプ |
ISSN |
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収録物識別子 |
0035-9203 |
| DOI |
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関連タイプ |
isVersionOf |
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|
識別子タイプ |
DOI |
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|
関連識別子 |
10.1016/j.trstmh.2008.09.014 |
| リンクURL |
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内容記述タイプ |
Other |
|
内容記述 |
http://dx.doi.org/10.1016/j.trstmh.2008.09.014 | http://dx.doi.org/10.1016/j.trstmh.2008.09.014 |
| 抄録 |
|
|
内容記述タイプ |
Abstract |
|
内容記述 |
Paragonimiasis is a common parasitic zoonosis in Cameroon and neighbouring countries in Western Africa. Serum, sputum and faecal samples were collected in an endemic area of South West Province, Cameroon, after administration of a questionnaire to identify individuals with appropriate symptoms and histories. Microscopic examination revealed eggs in sputum from 16 people, but none in any faecal sample. These 16 were among the 25 and 26 people, respectively, positive by ELISA and by immunoblot using Paragonimus africanus crude antigens. Copro-DNA detection was attempted using 23 faecal samples (18 from sputum egg-negative and five from sputum egg-positive individuals). Copro-DNA was detected in four of the five sputum egg-positive individuals. These results strongly suggest that: (1) serology is much more sensitive than sputum examination for diagnosis of paragonimiasis; and (2) a copro-DNA test may be more sensitive than a microscopic search for eggs in faeces. Molecular sequence data from ITS2 and cox1 genes confirmed that adult worms experimentally raised in cats were P. africanus and that eggs from sputum or other worm products from human faeces also belonged to this species. Based on these results, 26 of 168 persons (15.5%) were diagnosed as suffering from paragonimiasis. |
| 注記 |
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内容記述タイプ |
Other |
|
注記 |
author |
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言語 |
en |
| 資源タイプ |
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内容記述タイプ |
Other |
|
資源タイプ |
text |
| 著者版フラグ |
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出版タイプ |
AM |
| フォーマット |
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内容記述タイプ |
Other |
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内容記述 |
application/pdf |
| ID(XooNIps) |
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|
18992906 |
| 閲覧数(XooNIps) |
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| ダウンロード数(XooNIps) |
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|
1495 |
2034.pdf (954.6 kB)
