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How long do parthenogenetically activated mouse oocytes maintain the ability to accept sperm nuclei as a genetic partner?
https://asahikawa-med.repo.nii.ac.jp/records/148
https://asahikawa-med.repo.nii.ac.jp/records/14889e0966c-3832-42ac-8044-a12c398cf3a0
| 名前 / ファイル | ライセンス | アクション |
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228.pdf (761.5 kB)
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| Item type | 学術雑誌論文 / Journal Article_02(1) | |||||||||||
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| 公開日 | 2007-02-14 | |||||||||||
| タイトル | ||||||||||||
| タイトル | How long do parthenogenetically activated mouse oocytes maintain the ability to accept sperm nuclei as a genetic partner? | |||||||||||
| 言語 | en | |||||||||||
| 言語 | ||||||||||||
| 言語 | eng | |||||||||||
| 資源タイプ | ||||||||||||
| 資源タイプ | journal article | |||||||||||
| 著者 |
立野, 裕幸
× 立野, 裕幸
× Kamiguchi, Y
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| 著者 ローマ字 | ||||||||||||
| Tateno, Hiroyuki | ||||||||||||
| 書誌情報 |
JOURNAL OF ASSISTED REPRODUCTION AND GENETICS 巻 22, 号 2, p. 89-93, 発行日 2005-02-01 |
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| ISSN | ||||||||||||
| 収録物識別子タイプ | ISSN | |||||||||||
| 収録物識別子 | 1058-0468 | |||||||||||
| DOI | ||||||||||||
| 識別子タイプ | DOI | |||||||||||
| 関連識別子 | 10.1007/s10815-005-1498-0 | |||||||||||
| リンクURL | ||||||||||||
| 内容記述タイプ | Other | |||||||||||
| 内容記述 | http://www.springerlink.com/content/tj6275m2841kvlk2/?p=704d5ae0c6064c5083aae938666b00bc&pi=5 | http://www.springerlink.com/content/tj6275m2841kvlk2/?p=704d5ae0c6064c5083aae938666b00bc&pi=5 | |||||||||||
| 抄録 | ||||||||||||
| 内容記述タイプ | Abstract | |||||||||||
| 内容記述 | Purpose: Cytogenetic risk of intracytoplasmic sperm injection (ICSI) after artificial oocyte activation (post-activation ICSI) was evaluated in the mouse. Methods: Mouse zygotes were produced by ICSI into eggs at various intervals after parthenogenetic exposure to strontium (Sr) for 30 min. Male pronucleus formation and the chromosome constitution were studied. Results: Sperm nuclei injected into oocytes within 1 h after Sr exposure (from early through mid-telophase) transformed normally into male pronuclei, and the number of chromosome aberrations did not significantly increase in the resultant zygotes. When sperm nuclei were injected into eggs at intervals beyond 1 h after Sr exposure (from late telophase through the G1 pronuclear stage), the rate of male pronucleus formation was significantly reduced. The incidence of chromosome aberrations increased with time between oocyte activation and ICSI. Conclusions: ICSI into oocytes within 1 h after parthenogenetic activation produces cytogenetically competent embryos in the mouse. | |||||||||||
| 注記 | ||||||||||||
| 内容記述タイプ | Other | |||||||||||
| 注記 | The original publication is available at www.springerlink.com. \nauthor |
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| 資源タイプ | ||||||||||||
| 内容記述タイプ | Other | |||||||||||
| 資源タイプ | text | |||||||||||
| フォーマット | ||||||||||||
| 内容記述タイプ | Other | |||||||||||
| 内容記述 | application/pdf | |||||||||||
| ID(XooNIps) | ||||||||||||
| 15844734 | ||||||||||||
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| ダウンロード数(XooNIps) | ||||||||||||
| 760 | ||||||||||||
