{"created":"2023-06-19T11:20:51.671737+00:00","id":953,"links":{},"metadata":{"_buckets":{"deposit":"5ec4c38d-f202-43c6-852f-3db7c3167451"},"_deposit":{"created_by":3,"id":"953","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"953"},"status":"published"},"_oai":{"id":"oai:asahikawa-med.repo.nii.ac.jp:00000953","sets":["7","7:23"]},"author_link":["2894","2895","2896","2897"],"item_5_biblio_info_21":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2003-06-01","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"3","bibliographicPageEnd":"283","bibliographicPageStart":"277","bibliographicVolumeNumber":"15","bibliographic_titles":[{"bibliographic_title":"口腔・咽頭科"}]}]},"item_5_description_33":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"以前より,掌蹠膿疱症扁桃の病理組織において,T細胞領域の拡大が認められることが報告されている.このT細胞領域では,CD25陽性活性化T細胞の増加が認められ,T細胞制御因子(CTLA-4,Smad7)のmRNA発現低下が認められたことから,その拡大はT細胞の制御機構の障害による活性化,増殖によるものと推測された.T細胞制御の障害は無秩序な免疫反応を助長し,自己抗体産生につながることが予想され,このことが掌蹠膿疱症の病因に関与している可能性が示唆された.したがって,T細胞の活性化を表す指標が扁桃摘出術における術後の改善度を予測する因子になると予想される","subitem_description_language":"ja","subitem_description_type":"Abstract"}]},"item_5_description_36":{"attribute_name":"注記","attribute_value_mlt":[{"subitem_description":"著者版","subitem_description_type":"Other"}]},"item_5_description_37":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"subitem_description":"text","subitem_description_type":"Other"}]},"item_5_description_41":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_5_source_id_22":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0917-5105","subitem_source_identifier_type":"PISSN"}]},"item_5_text_44":{"attribute_name":"ID(XooNIps)","attribute_value_mlt":[{"subitem_text_value":"2003308158"}]},"item_5_text_54":{"attribute_name":"閲覧数(XooNIps)","attribute_value_mlt":[{"subitem_text_value":"1477"}]},"item_5_text_55":{"attribute_name":"ダウンロード数(XooNIps)","attribute_value_mlt":[{"subitem_text_value":"487"}]},"item_5_text_7":{"attribute_name":"著者 ローマ字","attribute_value_mlt":[{"subitem_text_value":"Takahara, Miki"},{"subitem_text_language":"en","subitem_text_value":"Nozawa, Hayabusa"},{"subitem_text_language":"en","subitem_text_value":"Kishibe, Kan"},{"subitem_text_language":"en","subitem_text_value":"Harabuchi, Yasuaki"},{"subitem_text_language":"en"}]},"item_5_version_type_38":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"高原, 幹","creatorNameLang":"ja"},{"creatorName":"タカハラ, ミキ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"2894","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"野沢, はやぶさ","creatorNameLang":"ja"},{"creatorName":"ノザワ, ハヤブサ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"2895","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"岸部, 幹","creatorNameLang":"ja"},{"creatorName":"キシベ, カン","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"2896","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"原渕, 保明","creatorNameLang":"ja"},{"creatorName":"ハラブチ, ヤスアキ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"2897","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2021-07-06"}],"displaytype":"detail","filename":"1152.pdf","filesize":[{"value":"210.2 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"1152.pdf","url":"https://asahikawa-med.repo.nii.ac.jp/record/953/files/1152.pdf"},"version_id":"396a2670-373f-4ff3-b543-6b207db6cf2d"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"掌蹠膿疱症の発症病態と扁桃摘出術の有効性","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"掌蹠膿疱症の発症病態と扁桃摘出術の有効性","subitem_title_language":"ja"}]},"item_type_id":"5","owner":"3","path":["6","7","23"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2008-08-28"},"publish_date":"2008-08-28","publish_status":"0","recid":"953","relation_version_is_last":true,"title":["掌蹠膿疱症の発症病態と扁桃摘出術の有効性"],"weko_creator_id":"3","weko_shared_id":-1},"updated":"2024-07-16T09:30:32.054276+00:00"}