{"created":"2023-06-19T11:20:42.743605+00:00","id":782,"links":{},"metadata":{"_buckets":{"deposit":"0005fb27-acb6-4d5c-86d4-26442c44b07e"},"_deposit":{"created_by":3,"id":"782","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"782"},"status":"published"},"_oai":{"id":"oai:asahikawa-med.repo.nii.ac.jp:00000782","sets":["7","7:23"]},"author_link":["2276","2277","2278","2279","2280"],"item_5_biblio_info_21":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2007-09-01","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"2","bibliographicPageEnd":"229","bibliographicPageStart":"228","bibliographicVolumeNumber":"25","bibliographic_titles":[{"bibliographic_title":"耳鼻咽喉科免疫アレルギー"}]}]},"item_5_description_33":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"掌蹠膿疱症9例、反復性扁桃炎11例の摘出扁桃より単核球を分離し、PE標識抗CD3抗体およびFITC標識抗CD29抗体を用いて2重染色し、フローサイトメトリーを用いて解析した。また掌蹠膿疱症8例、反復性扁桃炎8例の摘出扁桃のパラフィン包埋切片を用いて、抗VCAM-1抗体にて免疫染色を行い、ImageJを用いて発現強度を検討した。結果として、VCAM-1の発現強度に関しては両疾患群間に差はみられなかったが、掌蹠膿疱症群では反復性扁桃炎群に比し、CD3陽性細胞中のCD3CD29陽性細胞および全単核球中のCD3CD29陽性細胞の割合が有意に上昇していた。この事から、T細胞の活性化にCD29が関与している可能性が示唆された。","subitem_description_language":"ja","subitem_description_type":"Abstract"}]},"item_5_description_36":{"attribute_name":"注記","attribute_value_mlt":[{"subitem_description":"出版社版 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