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Chronic health effects in people exposed to arsenic via the drinking water: dose-response relationships in review
https://asahikawa-med.repo.nii.ac.jp/records/650
https://asahikawa-med.repo.nii.ac.jp/records/650876bedad-7037-472b-ad51-f1acd5972de2
名前 / ファイル | ライセンス | アクション |
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Item type | 学術雑誌論文 / Journal Article_02(1) | |||||||||||||
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公開日 | 2007-12-03 | |||||||||||||
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タイトル | Chronic health effects in people exposed to arsenic via the drinking water: dose-response relationships in review | |||||||||||||
言語 | en | |||||||||||||
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言語 | eng | |||||||||||||
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資源タイプ | journal article | |||||||||||||
著者 |
吉田, 貴彦
× 吉田, 貴彦
× Yamauchi, H
× Fan, Sun Gui
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著者 ローマ字 | ||||||||||||||
Yoshida, Takahiko | ||||||||||||||
書誌情報 |
Toxicology & Applied Pharmacology 巻 198, 号 3, p. 243-252, 発行日 2004-08-01 |
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ISSN | ||||||||||||||
収録物識別子タイプ | ISSN | |||||||||||||
収録物識別子 | 0041-008X | |||||||||||||
DOI | ||||||||||||||
関連タイプ | isVersionOf | |||||||||||||
識別子タイプ | DOI | |||||||||||||
関連識別子 | 10.1016/j.taap.2003.10.022 | |||||||||||||
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内容記述タイプ | Other | |||||||||||||
内容記述 | http://www.sciencedirect.com/science/journal/0041008X | http://www.sciencedirect.com/science/journal/0041008X | |||||||||||||
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内容記述タイプ | Abstract | |||||||||||||
内容記述 | Chronic arsenic (As) poisoning has become a worldwide public health issue. Most human As exposure occurs from consumption of drinking water containing high amounts of inorganic As (iAs). In this paper, epidemiological studies conducted on the dose–response relationships between iAs exposure via the drinking water and related adverse health effects are reviewed. Before the review, the methods for evaluation of the individual As exposure are summarized and classified into two types, that is, the methods depending on As concentration of the drinking water and the methods depending on biological monitoring for As exposure; certain methods may be applied as optimum As exposure indexes to study dose–response relationship based on various As exposure situation. Chronic effects of iAs exposure via drinking water include skin lesions, neurological effects, hypertension, peripheral vascular disease, cardiovascular disease, respiratory disease, diabetes mellitus, and malignancies including skin cancer. The skin is quite sensitive to arsenic, and skin lesions are some of the most common and earliest nonmalignant effects related to chronic As exposure. The increase of prevalence in the skin lesions has been observed even at the exposure levels in the range of 0.005–0.01 mg/l As in drinking waters. Skin, lung, bladder, kidney, liver, and uterus are considered as sites As-induced malignancies, and the skin is though to be perhaps the most sensitive site. Prospective studies in large area of endemic As poisoning, like Bangladesh or China, where the rate of malignancies is expected to increase within the next several decades, will help to clarify the dose–response relationship between As exposure levels and adverse health effects with enhanced accuracy. | |||||||||||||
注記 | ||||||||||||||
内容記述タイプ | Other | |||||||||||||
注記 | Academic Press, Yoshida, Takahiko ; Yamauchi, Hiroshi ; Fan Sun, Gui, Toxicology & Applied Pharmacology, 198(3), 2004, 243-252. \nauthor |
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内容記述タイプ | Other | |||||||||||||
資源タイプ | text | |||||||||||||
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出版タイプ | AM | |||||||||||||
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内容記述タイプ | Other | |||||||||||||
内容記述 | application/pdf | |||||||||||||
ID(XooNIps) | ||||||||||||||
15276403 | ||||||||||||||
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973 |