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Spinal cord transection inhibits HR reduction in anesthetized rats immersed in an artificial CO2-hot spring bath

https://asahikawa-med.repo.nii.ac.jp/records/642
https://asahikawa-med.repo.nii.ac.jp/records/642
71b08e3d-1fba-4a85-bbba-155f493535ac
名前 / ファイル ライセンス アクション
803.pdf 803.pdf (403.7 kB)
Item type 学術雑誌論文 / Journal Article_02(1)
公開日 2007-12-03
タイトル
タイトル Spinal cord transection inhibits HR reduction in anesthetized rats immersed in an artificial CO2-hot spring bath
言語 en
言語
言語 eng
資源タイプ
資源タイプ journal article
著者 山本, 憲志

× 山本, 憲志

山本, 憲志

ja-Kana ヤマモト, ノリユキ

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Hashimoto, M

× Hashimoto, M

Hashimoto, M

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著者 ローマ字
Yamamoto, Noriyuki
書誌情報 International Journal of Biometeorology

巻 51, 号 3, p. 201-208, 発行日 2007-01-01
ISSN
収録物識別子タイプ ISSN
収録物識別子 0020-7128
DOI
識別子タイプ DOI
関連識別子 10.1007/s00484-006-0055-6
リンクURL
内容記述タイプ Other
内容記述 http://springerlink.metapress.com/content/0173358776782072/?p=4250df8a5d774cea89407d4b512eec41&pi=3 | http://springerlink.metapress.com/content/0173358776782072/?p=4250df8a5d774cea89407d4b512eec41&pi=3
抄録
内容記述タイプ Abstract
内容記述 Like humans, the heart rate (HR) of anesthetized rats immersed in CO2-water is lower than that when immersed in tap water at the same temperature. To investigate the afferent signal pathway in the mechanism of HR reduction, Wistar rats were anesthetized with urethane and then the spinal cord was transected between T4 and T5. The animals were immersed up to the axilla in a bathtub of tap-water (CO2 contents: 10–20 mg·l−1) or of CO2-water (965–1,400 mg·l−1) at 35°C while recording HR, arterial blood pressure, and arterial blood gas parameters (PaCO2, PaO2, pH). Arterial blood gas parameters did not change during immersion, irrespective of CO2 concentration of the bath water, whereas the HR was reduced in the CO2-water bath. The inhalation of CO2-mixed gas (5 % CO2, 20 % O2, 75 % N2) resulted in increased levels of blood gases and an increased HR during immersion in all types of water tested. The HR reduction observed in sham transected control animals immersed in CO2-water disappeared after subsequent spinal cord transection. These results show that the dominant afferent signal pathway to the brain, which is involved in inducing the reduced HR during immersion in CO2-water, is located in the neuronal route and not in the bloodstream.
注記
内容記述タイプ Other
注記 This is the author-created version of Springer, Yamamoto, Noriyuki ; Hashimoto, Masaaki, International Journal of Biometeorology, 51(3), 2007, 201-208. The original publication is available at www.springerlink.com.
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資源タイプ text
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