{"created":"2023-06-19T11:25:24.396436+00:00","id":6257,"links":{},"metadata":{"_buckets":{"deposit":"791c1817-df6c-4c22-9640-d490d719c355"},"_deposit":{"created_by":3,"id":"6257","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"6257"},"status":"published"},"_oai":{"id":"oai:asahikawa-med.repo.nii.ac.jp:00006257","sets":["7","7:27:45"]},"author_link":["19655"],"control_number":"6257","item_10_alternative_title_3":{"attribute_name":"その他（別言語等）のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"複数回ボツリヌス療法を実施した脳卒中患者における痙縮および関節可動域の経時的変化","subitem_alternative_title_language":"ja"}]},"item_10_biblio_info_21":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2020-01-01","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1","bibliographicPageStart":"104481","bibliographicVolumeNumber":"29","bibliographic_titles":[{"bibliographic_title":"Journal of Stroke and Cerebrovascular Diseases"}]}]},"item_10_date_granted_30":{"attribute_name":"学位授与年月日","attribute_value_mlt":[{"subitem_dategranted":"2020-03-25"}]},"item_10_degree_grantor_32":{"attribute_name":"学位授与機関","attribute_value_mlt":[{"subitem_degreegrantor":[{"subitem_degreegrantor_name":"旭川医科大学"}],"subitem_degreegrantor_identifier":[{}]}]},"item_10_degree_name_31":{"attribute_name":"学位名","attribute_value_mlt":[{"subitem_degreename":"博士（医学）"}]},"item_10_description_28":{"attribute_name":"識別番号 その他","attribute_value_mlt":[{"subitem_description":"PMID: 31699575","subitem_description_type":"Other"}]},"item_10_description_33":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Objective: This study examined how the effects of botulinum toxin therapy changed over time by sequential evaluation of clinical improvements in spasticity and contracture in 24 chronic-stage stroke patients on repeated botulinum toxin therapy who were receiving fewer rehabilitation interventions.\n\\nMethods: Botulinum toxin injection was administered into the spastic muscle of the paralyzed upper or lower limb 5 times with at least 3-month intervals. Modified Ashworth Scale and range of motion were measured before and 2 weeks after each dose in the extremities to compare the first measurement value with subsequent values. Each predose value was also compared with the first predose value.\n\\nResults: Compared with predose scores, Modified Ashworth Scale significantly improved in all flexors after 2 weeks from the first to fifth doses. Range of motion significantly improved in wrist dorsiflexion and ankle dorsiflexion. Comparison of values before each dose versus the first predose value showed significant improvement both in the Modified Ashworth Scale score of wrist flexors, finger flexors, and ankle planter flexors, and the range of motion of elbow extension, wrist dorsiflexion, and ankle dorsiflexion.\n\\nConclusion: The comparison of predose values versus 2-week postdose values indicated that the effect of botulinum toxin formulation would not lessen after repeated injections with continuous improvements of Modified Ashworth Scale and range of motion. The comparison of predose values versus the first predose value also suggested that multiple injections of botulinum toxin formulation could be more effective in reducing spasticity and increasing the range of motion than a single injection.","subitem_description_type":"Abstract"}]},"item_10_description_37":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_10_description_41":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_10_dissertation_number_29":{"attribute_name":"学位授与番号","attribute_value_mlt":[{"subitem_dissertationnumber":"甲540"}]},"item_10_relation_24":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"10.1016/j.jstrokecerebrovasdis.2019.104481.","subitem_relation_type_select":"DOI"}}]},"item_10_text_7":{"attribute_name":"著者 ローマ字","attribute_value_mlt":[{"subitem_text_value":"Ro, Takanori"}]},"item_10_version_type_38":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_abf2"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"呂, 隆徳","creatorNameLang":"ja"},{"creatorName":"ロ, タカノリ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2021-07-06"}],"filename":"7549.pdf","filesize":[{"value":"13.8 MB"}],"format":"application/pdf","mimetype":"application/pdf","url":{"label":"7549.pdf","url":"https://asahikawa-med.repo.nii.ac.jp/record/6257/files/7549.pdf"},"version_id":"de51bbce-7206-4bcc-ac6d-b677f036ecc3"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Modified Ashworth Scale","subitem_subject_scheme":"Other"},{"subitem_subject":"Spasticity","subitem_subject_scheme":"Other"},{"subitem_subject":"botulinum toxin A therapy","subitem_subject_scheme":"Other"},{"subitem_subject":"range of motion","subitem_subject_scheme":"Other"},{"subitem_subject":"stroke","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"doctoral thesis","resourceuri":"http://purl.org/coar/resource_type/c_db06"}]},"item_title":"Spasticity and Range of Motion Over Time in Stroke Patients who Received MultiI542:I548ple Dose Botulinum Toxin Therapy","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Spasticity and Range of Motion Over Time in Stroke Patients who Received MultiI542:I548ple Dose Botulinum Toxin Therapy","subitem_title_language":"en"}]},"item_type_id":"10","owner":"3","path":["6","7","45"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2021-04-23"},"publish_date":"2021-04-23","publish_status":"0","recid":"6257","relation_version_is_last":true,"title":["Spasticity and Range of Motion Over Time in Stroke Patients who Received MultiI542:I548ple Dose Botulinum Toxin Therapy"],"weko_creator_id":"3","weko_shared_id":-1},"updated":"2024-04-10T11:13:32.767649+00:00"}