{"created":"2023-06-19T11:25:15.182205+00:00","id":6079,"links":{},"metadata":{"_buckets":{"deposit":"bc23c25a-ac08-43da-9d0b-8b70d9c2c91f"},"_deposit":{"created_by":3,"id":"6079","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"6079"},"status":"published"},"_oai":{"id":"oai:asahikawa-med.repo.nii.ac.jp:00006079","sets":["7","7:27:41"]},"author_link":["19110"],"item_10_biblio_info_21":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2019-01-01","bibliographicIssueDateType":"Issued"},"bibliographic_titles":[{"bibliographic_title":"Journal of intensive care medicine"}]}]},"item_10_degree_grantor_32":{"attribute_name":"学位授与機関","attribute_value_mlt":[{"subitem_degreegrantor":[{"subitem_degreegrantor_name":"旭川医科大学"}]}]},"item_10_degree_name_31":{"attribute_name":"学位名","attribute_value_mlt":[{"subitem_degreename":"博士（医学）"}]},"item_10_description_28":{"attribute_name":"識別番号 その他","attribute_value_mlt":[{"subitem_description":"PMID：30636495","subitem_description_type":"Other"}]},"item_10_description_33":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"BACKGROUND::\n\\nCurrently, it remains controversial whether the Sepsis-3 definition provides the most appropriate criteria for clinical use. The purpose of this study was to compare between the Sepsis-2 and Sepsis-3 definitions using Japan's nationwide registry.\nMETHODS::\n\\nData were obtained from a multicenter registry conducted at 42 intensive care units (ICUs) throughout Japan, in which patients received treatment for severe sepsis or septic shock between January 2011 and December 2013.\nRESULTS::\n\\nA total of 2797 patients diagnosed using the Sepsis-2 criteria were included in the present study. These patients were categorized into \"Severe sepsis\" (n = 1154) and \"Sepsis-2 shock\" (n = 1643) groups. Among the \"Sepsis-2 shock\" group, patients who did not meet the Sepsis-3 criteria for septic shock were categorized into the \"Sepsis-2 shock-only\" (n = 448, 27.3%) group, while patients who met the Sepsis-3 criteria for septic shock were categorized into \"Sepsis-3 shock (n = 1195, 72.7%)\" group. The ICU mortality in the \"Sepsis-3 shock\" group, \"Sepsis-2 shock-only\" group, and \"Severe sepsis\" group was 28.5%, 10.9%, and 14.1%, respectively. We observed no significant difference between the \"Severe sepsis\" and \"Sepsis-2 shock-only\" groups in terms of in-hospital survival ( P = .098), while the \"Sepsis-3 shock\" group had the highest in-hospital mortality rate ( P < .001). In a multivariate logistic regression analysis, liver insufficiency and immunocompromised status were independent prognostic factors in the \"Sepsis-2 shock-only\" group. In contrast, chronic heart disease and chronic hemodialysis were independent prognostic factors in the \"Sepsis-3 shock\" group.\nCONCLUSIONS::\n\\nThe ICU mortality of the \"Sepsis-2 shock-only\" group was significantly low. Besides septic shock diagnosed by the Sepsis-3 definition selects patients with more severe cases of sepsis among the \"Sepsis-2 shock\" group.","subitem_description_type":"Abstract"}]},"item_10_description_37":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_10_description_41":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_10_dissertation_number_29":{"attribute_name":"学位授与番号","attribute_value_mlt":[{"subitem_dissertationnumber":"10107B481"}]},"item_10_relation_24":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"10.1177/0885066618823151","subitem_relation_type_select":"DOI"}}]},"item_10_source_id_22":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0885-0666","subitem_source_identifier_type":"ISSN"}]},"item_10_text_7":{"attribute_name":"著者 ローマ字","attribute_value_mlt":[{"subitem_text_value":"Takauji, Shuhei"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"高氏, 修平","creatorNameLang":"ja"},{"creatorName":"タカウジ, シュウヘイ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"19110","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2021-07-06"}],"displaytype":"detail","filename":"7256.pdf","filesize":[{"value":"131.3 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"7256.pdf","url":"https://asahikawa-med.repo.nii.ac.jp/record/6079/files/7256.pdf"},"version_id":"488f0e86-c378-40ed-b82d-4fe8442d7f0d"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Sepsis-3","subitem_subject_scheme":"Other"},{"subitem_subject":"mortality","subitem_subject_scheme":"Other"},{"subitem_subject":"organ failure","subitem_subject_scheme":"Other"},{"subitem_subject":"septic shock","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"thesis","resourceuri":"http://purl.org/coar/resource_type/c_46ec"}]},"item_title":"A nationwide comparison between Sepsis-2 and Sepsis-3 definition in Japan","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"A nationwide comparison between Sepsis-2 and Sepsis-3 definition in Japan","subitem_title_language":"en"}]},"item_type_id":"10","owner":"3","path":["6","7","41"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2019-08-01"},"publish_date":"2019-08-01","publish_status":"0","recid":"6079","relation_version_is_last":true,"title":["A nationwide comparison between Sepsis-2 and Sepsis-3 definition in Japan"],"weko_creator_id":"3","weko_shared_id":-1},"updated":"2024-04-09T06:59:46.534600+00:00"}