{"created":"2023-06-19T11:20:33.461229+00:00","id":604,"links":{},"metadata":{"_buckets":{"deposit":"2dbf82e5-8c6f-439c-b621-024e3993ac36"},"_deposit":{"created_by":3,"id":"604","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"604"},"status":"published"},"_oai":{"id":"oai:asahikawa-med.repo.nii.ac.jp:00000604","sets":["7","7:23"]},"author_link":["1328","1329","1330","1331","1332","1333","1334"],"item_5_biblio_info_21":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2003-06-01","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"2","bibliographicPageEnd":"209","bibliographicPageStart":"208","bibliographicVolumeNumber":"21","bibliographic_titles":[{"bibliographic_title":"耳鼻咽喉科免疫アレルギー"}]}]},"item_5_description_33":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"ペプチドワクチン開発の基礎的研究として,健常人末梢血より分離したCD4陽性細胞及び樹状細胞を用いてP6蛋白に特異的に反応するT細胞株を樹立し,その反応性について解析した.樹立した,P6外膜蛋白反応性T細胞株は,P6蛋白のオーバーラッピングペプチドの8番のペプチド内に,エピトープが存在し,T細胞株は,HLA-DR9分子を介してP6蛋白の抗原提示をうけていた.DR9分子保有者に対するP6蛋白のペプチドワクチン療法として,P6蛋白のオーバーラッピングペプチドの8番のペプチドがそのワクチン抗原の一つになる可能性が示唆された","subitem_description_language":"ja","subitem_description_type":"Abstract"}]},"item_5_description_36":{"attribute_name":"注記","attribute_value_mlt":[{"subitem_description":"出版社版 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