{"created":"2023-06-19T11:25:05.859826+00:00","id":5915,"links":{},"metadata":{"_buckets":{"deposit":"d29754ce-35fa-4115-953e-17c296f44aa0"},"_deposit":{"created_by":1,"id":"5915","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"5915"},"status":"published"},"_oai":{"id":"oai:asahikawa-med.repo.nii.ac.jp:00005915","sets":["7","7:24"]},"author_link":["18561","18565","18559","18567","18564","18566","18569","18560","18563","18562","18568"],"item_5_biblio_info_21":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2017-08-01","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1","bibliographicPageStart":"54","bibliographicVolumeNumber":"16","bibliographic_titles":[{"bibliographic_title":"Annals of Clinical Microbiology and Antimicrobials"}]}]},"item_5_description_28":{"attribute_name":"識別番号 その他","attribute_value_mlt":[{"subitem_description":"PMID：28806959","subitem_description_type":"Other"}]},"item_5_description_33":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"OBJECTIVE:\n\\nHelicobacter pylori (H. pylori) eradication rarely develops into antibiotic-associated hemorrhagic colitis (AAHC), in which the etiology of colitis remains unclear. We herein report a rare case of AAHC caused by second-line therapy for H. pylori eradication.\nRESULTS:\n\\nA 65-year-old female was administered second-line therapy for H. pylori composed of 1500 mg of amoxicillin, 500 mg of metronidazole and 40 mg of vonoprazan for 7 days because of first-line therapy failure. A day after completing second-line therapy, she complained of abdominal pain and hematochezia. Colonoscopy revealed a hemorrhage and edematous mucosa with no transparent vascular pattern in the transverse colon. A bacterial culture detected Klebsiella oxytoca (K. oxytoca), but no other pathogenic bacteria. A drug-induced lymphocyte stimulation test (DLST) showed positive reactions for both amoxicillin and metronidazole. According to these findings, the patient was diagnosed with AAHC. Bowel rest for 6 days relieved her abdominal pain and hematochezia.\nCONCLUSIONS:\n\\nThe present case developed AAHC caused by second-line therapy for H. pylori eradication. The pathogenesis is considered to be associated with microbial substitution as well as a delayed-type allergy to antibiotics, suggesting that AAHC is a potential adverse event of second-line therapy for H. pylori eradication.","subitem_description_type":"Abstract"}]},"item_5_description_36":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/)","subitem_description_type":"Other"}]},"item_5_description_37":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"subitem_description":"text","subitem_description_type":"Other"}]},"item_5_description_41":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_5_relation_24":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"10.1186/s12941-017-0230-0","subitem_relation_type_select":"DOI"}}]},"item_5_source_id_22":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1476-0711","subitem_source_identifier_type":"ISSN"}]},"item_5_text_44":{"attribute_name":"ID(XooNIps)","attribute_value_mlt":[{"subitem_text_value":"28806959"}]},"item_5_text_54":{"attribute_name":"閲覧数(XooNIps)","attribute_value_mlt":[{"subitem_text_value":"347"}]},"item_5_text_55":{"attribute_name":"ダウンロード数(XooNIps)","attribute_value_mlt":[{"subitem_text_value":"494"}]},"item_5_text_7":{"attribute_name":"著者 ローマ字","attribute_value_mlt":[{"subitem_text_value":"Tanaka, Kazuyuki"},{"subitem_text_value":"Fujiya, Mikihiro"},{"subitem_text_value":"Sakatani, Aki"},{"subitem_text_value":"Fujibayashi, Shugo"},{"subitem_text_value":"Nomura, Yoshiki"},{"subitem_text_value":"Ueno, Nobuhiro"},{"subitem_text_value":"Kashima, Shin"},{"subitem_text_value":"Goto, Takuma"},{"subitem_text_value":"Sasajima, Junpei"},{"subitem_text_value":"Moriichi, Kentaro"},{"subitem_text_value":"Okumura, Toshikatsu"}]},"item_5_version_type_38":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"田中, 一之"},{"creatorName":"タナカ, カズユキ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"18559","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"藤谷, 幹浩"},{"creatorName":"フジヤ, ミキヒロ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"18560","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"坂谷, 慧"},{"creatorName":"サカタニ, アキ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"18561","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"藤林, 周吾"},{"creatorName":"フジバヤシ, シュウゴ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"18562","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"野村, 好紀"},{"creatorName":"ノムラ, ヨシキ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"18563","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"上野, 伸展"},{"creatorName":"ウエノ, ノブヒロ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"18564","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"嘉島, 伸"},{"creatorName":"カシマ, シン","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"18565","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"後藤, 拓磨"},{"creatorName":"ゴトウ, タクマ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"18566","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"笹島, 順平"},{"creatorName":"ササジマ, ジュンペイ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"18567","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"盛一, 健太郎"},{"creatorName":"モリイチ, ケンタロウ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"18568","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"奥村, 利勝"},{"creatorName":"オクムラ, トシカツ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"18569","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2021-07-06"}],"displaytype":"detail","filename":"7030.pdf","filesize":[{"value":"1.1 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"7030.pdf","url":"https://asahikawa-med.repo.nii.ac.jp/record/5915/files/7030.pdf"},"version_id":"88a22bca-0cc9-4f6c-9a8c-6dced0ce5c14"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Second-line therapy for Helicobacter pylori eradication causing antibiotic-associated hemorrhagic colitis","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Second-line therapy for Helicobacter pylori eradication causing antibiotic-associated hemorrhagic colitis"}]},"item_type_id":"5","owner":"1","path":["6","7","24"],"pubdate":{"attribute_name":"公開日","attribute_value":"2018-07-25"},"publish_date":"2018-07-25","publish_status":"0","recid":"5915","relation_version_is_last":true,"title":["Second-line therapy for Helicobacter pylori eradication causing antibiotic-associated hemorrhagic colitis"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-06-19T12:08:20.626781+00:00"}