{"created":"2023-06-19T11:25:04.823798+00:00","id":5894,"links":{},"metadata":{"_buckets":{"deposit":"435a09ee-4a77-4dd7-a800-6afe2d0039ca"},"_deposit":{"created_by":1,"id":"5894","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"5894"},"status":"published"},"_oai":{"id":"oai:asahikawa-med.repo.nii.ac.jp:00005894","sets":["7","7:24"]},"author_link":["18436","18437","18443","18441","18438","18440","18442","18439","18444","18445"],"item_5_biblio_info_21":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2016-05-01","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"4","bibliographicPageEnd":"1238","bibliographicPageStart":"1234","bibliographicVolumeNumber":"48","bibliographic_titles":[{"bibliographic_title":"Transplantation proceedings"}]}]},"item_5_description_33":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"BACKGROUND:\n\\nThe use of grafts from donors after cardiac death (DCD) would greatly contribute to the expansion of the donor organ pool. The objective of this study is to determine the benefits of extracorporeal membrane oxygenation (ECMO) and subnormothermic machine perfusion (MP) with rewarming in a large animal model of DCD liver.\nMETHODS:\n\\nAfter cardiac arrest, the abdominal aorta and the inferior vena cava were cannulated and connected to an ECMO circuit. Porcine livers were perfused in situ with ECMO at 22°C for 60 minutes after 60 minutes of cardiac death. Then the livers were perfused for 4 hours by MP as a graft viability test. In group 1, non-in situ ECMO and grafts were preserved hypothermic MP. In group 2, non-in situ ECMO and grafts were preserved subnormothermic rewarming MP. In group 3, we used ECMO and subnormothermic rewarming MP. To assess potential methods and effect, effluent enzymes were measured. Portal vein and hepatic artery pressure during MP were evaluated.\nRESULTS:\n\\nEffluent enzyme of AST, alanine aminotransferase and LDH as viability markers were significantly low (aspartate aminotransferase, 2899, 2292, and 972 IU/L; alanine aminotransferase, 134, 140, and 72 IU/L; and lactate dehydrogenase, 4354, 4455, and 1855 IU/L in each group, respectively). Portal vein and hepatic artery pressure during preservation came down smoothly in group 3 compared with group 1.\nCONCLUSIONS:\n\\nThe combined use of in situ subnormothermic ECMO and machine preservation with rewarming is more essential for the recovery and resuscitating function of DCD liver grafts.","subitem_description_type":"Abstract"}]},"item_5_description_36":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"This is an open access article under the CC BY-NC-ND license. (http://creativecommons.org/licenses/by-nc-nd/4.0/).","subitem_description_type":"Other"}]},"item_5_description_37":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"subitem_description":"text","subitem_description_type":"Other"}]},"item_5_description_41":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_5_relation_24":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isVersionOf","subitem_relation_type_id":{"subitem_relation_type_id_text":"10.1016/j.transproceed.2015.12.087","subitem_relation_type_select":"DOI"}}]},"item_5_source_id_22":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0041-1345","subitem_source_identifier_type":"ISSN"}]},"item_5_text_44":{"attribute_name":"ID(XooNIps)","attribute_value_mlt":[{"subitem_text_value":"27320594"}]},"item_5_text_54":{"attribute_name":"閲覧数(XooNIps)","attribute_value_mlt":[{"subitem_text_value":"453"}]},"item_5_text_55":{"attribute_name":"ダウンロード数(XooNIps)","attribute_value_mlt":[{"subitem_text_value":"506"}]},"item_5_text_7":{"attribute_name":"著者 ローマ字","attribute_value_mlt":[{"subitem_text_value":"Hagiwara, Masahiro"},{"subitem_text_value":"Matsuno, Naoto"},{"subitem_text_value":"&EMPTY&"},{"subitem_text_value":"Furukori, Mariko"},{"subitem_text_value":"Watanabe, Kenji"},{"subitem_text_value":"Shonaka, Tatsuya"},{"subitem_text_value":"Imai, Koji"},{"subitem_text_value":"Obara, Hiromichi"},{"subitem_text_value":"Nishikawa, Yuji"},{"subitem_text_value":"Furukawa, Hiroyuki"}]},"item_5_version_type_38":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"萩原, 正弘"},{"creatorName":"ハギワラ, マサヒロ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"18436","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"松野, 直徒"},{"creatorName":"マツノ, ナオト","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"18437","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Ling, tong  Meng"}],"nameIdentifiers":[{"nameIdentifier":"18438","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"古郡, 茉利子"},{"creatorName":"フルコリ, マリコ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"18439","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"渡邉, 賢二"},{"creatorName":"ワタナベ, ケンジ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"18440","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"庄中, 達也"},{"creatorName":"ショウナカ, タツヤ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"18441","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"今井, 浩二"},{"creatorName":"イマイ, コウジ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"18442","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"小原, 弘道"},{"creatorName":"オバラ, ヒロミチ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"18443","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"西川, 祐司"},{"creatorName":"ニシカワ, ユウジ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"18444","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"古川, 博之"},{"creatorName":"フルカワ, ヒロユキ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"18445","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2021-07-06"}],"displaytype":"detail","filename":"7001.pdf","filesize":[{"value":"5.4 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"7001.pdf","url":"https://asahikawa-med.repo.nii.ac.jp/record/5894/files/7001.pdf"},"version_id":"710e012b-2aa9-49b1-bbfd-67f0a1018411"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Applicability of Combined Use of Extracorporeal Support and Temperature-Controlled Machine Perfusion Preservation for Liver Procurement of Donors After Cardiac Death in Pigs.","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Applicability of Combined Use of Extracorporeal Support and Temperature-Controlled Machine Perfusion Preservation for Liver Procurement of Donors After Cardiac Death in Pigs."}]},"item_type_id":"5","owner":"1","path":["6","7","24"],"pubdate":{"attribute_name":"公開日","attribute_value":"2018-05-31"},"publish_date":"2018-05-31","publish_status":"0","recid":"5894","relation_version_is_last":true,"title":["Applicability of Combined Use of Extracorporeal Support and Temperature-Controlled Machine Perfusion Preservation for Liver Procurement of Donors After Cardiac Death in Pigs."],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-06-19T12:08:52.605646+00:00"}