{"created":"2023-06-19T11:20:31.028117+00:00","id":559,"links":{},"metadata":{"_buckets":{"deposit":"879f6e92-d1e0-44f6-bb44-ed79f4c6045e"},"_deposit":{"created_by":3,"id":"559","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"559"},"status":"published"},"_oai":{"id":"oai:asahikawa-med.repo.nii.ac.jp:00000559","sets":["7","7:23"]},"author_link":["1039","1040","1041","1042","1043"],"item_5_biblio_info_21":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2005-05-01","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1","bibliographicPageEnd":"162","bibliographicPageStart":"159","bibliographicVolumeNumber":"23","bibliographic_titles":[{"bibliographic_title":"日本耳鼻咽喉科感染症研究会会誌"}]}]},"item_5_description_33":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"治療を行った鼻性NK/T細胞リンパ腫および健常人からEpstetin-Barr(EB)ウイルス DNAを回収し,PCR法で対象とする遺伝子領域を増幅した.次にEBウイルスが感染した際,宿主の細胞膜上に発現を認める蛋白Latent membrane protein(LMP)-1,LMP-2AについてPCR direct sequencingを施行して両遺伝子塩基配列を決定し,これまでに報告のあるLMP-1,LMP-2A上のエピトープ配列に関して解析した.1)LMP-1におけるエピトープは,東アジア由来のAkata,1510,CAO,DV-Asp335株の配列が,NK/T細胞リンパ腫由来の株の配列と近似していた.2)エピトープ配列は,アジアの健常ヒト由来のアミノ酸配列の報告と比較しても,多くはAkata株やNK/T細胞リンパ腫等に認められるものと同じ配列であった.3)エピトープ領域のアミノ酸配列は,疾患に特異的ではなく,地域性を反映して保存されていると考えられた.4)LMP-2Aでは,検討し得た2ヶ所のエピトープ配列は,自験症例間では全て一致しており,LMP-1同様,よく保存されていた","subitem_description_language":"ja","subitem_description_type":"Abstract"}]},"item_5_description_36":{"attribute_name":"注記","attribute_value_mlt":[{"subitem_description":"著者版","subitem_description_type":"Other"}]},"item_5_description_37":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"subitem_description":"text","subitem_description_type":"Other"}]},"item_5_description_41":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_5_source_id_22":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0913-3976","subitem_source_identifier_type":"PISSN"}]},"item_5_text_44":{"attribute_name":"ID(XooNIps)","attribute_value_mlt":[{"subitem_text_value":"2005203582"}]},"item_5_text_54":{"attribute_name":"閲覧数(XooNIps)","attribute_value_mlt":[{"subitem_text_value":"2174"}]},"item_5_text_55":{"attribute_name":"ダウンロード数(XooNIps)","attribute_value_mlt":[{"subitem_text_value":"1371"}]},"item_5_text_7":{"attribute_name":"著者 ローマ字","attribute_value_mlt":[{"subitem_text_value":"Nagamine, Masayoshi"},{"subitem_text_language":"en","subitem_text_value":"Bando, Nobuyuki"},{"subitem_text_language":"en","subitem_text_value":"Takahara, Miki"},{"subitem_text_language":"en","subitem_text_value":"Ogino, Takeshi"},{"subitem_text_language":"en","subitem_text_value":"Harabuchi, Yasuaki"},{"subitem_text_language":"en"}]},"item_5_version_type_38":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"長峯, 正泰","creatorNameLang":"ja"},{"creatorName":"ナガミネ, マサヨシ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"1039","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"坂東, 伸幸","creatorNameLang":"ja"},{"creatorName":"バンドウ, 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